Cancer stem-like sphere cells induced from de-differentiated hepatocellular carcinoma-derived cell lines possess the resistance to anti-cancer drugs

[1]  S. Okazaki,et al.  Redox regulation in stem-like cancer cells by CD44 variant isoforms , 2013, Oncogene.

[2]  K. Mimori,et al.  Increased CD13 Expression Reduces Reactive Oxygen Species, Promoting Survival of Liver Cancer Stem Cells via an Epithelial–Mesenchymal Transition-like Phenomenon , 2012, Annals of Surgical Oncology.

[3]  M. Zern,et al.  Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. , 2011, Journal of hepatology.

[4]  R. Weinberg,et al.  Phenotypic plasticity and epithelial‐mesenchymal transitions in cancer and normal stem cells? , 2011, International journal of cancer.

[5]  Meng-chao Wu,et al.  Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines , 2011, BMC gastroenterology.

[6]  M. Kudo,et al.  Phase III trial of sunitinib (Su) versus sorafenib (So) in advanced hepatocellular carcinoma (HCC). , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[7]  M. Gottesman,et al.  Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer. , 2011, Current pharmaceutical biotechnology.

[8]  Hongxiang Liu,et al.  CD133: a potential indicator for differentiation and prognosis of human cholangiocarcinoma , 2011, BMC Cancer.

[9]  A. Allan,et al.  The Role of Human Aldehyde Dehydrogenase in Normal and Cancer Stem Cells , 2011, Stem Cell Reviews and Reports.

[10]  Chunxiao Zhou,et al.  Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem cells. , 2010, Cancer letters.

[11]  K. Sugamura,et al.  Characterization of the epithelial cell adhesion molecule (EpCAM)+ cell population in hepatocellular carcinoma cell lines , 2010, Cancer science.

[12]  T. Cramer,et al.  HIFs as central regulators of gastric cancer pathogenesis , 2010, Cancer biology & therapy.

[13]  A. Krešo,et al.  Cancer Stem Cells and Self-renewal , 2010, Clinical Cancer Research.

[14]  C. Tiribelli,et al.  Hepatic cancer stem cells and drug resistance: Relevance in targeted therapies for hepatocellular carcinoma. , 2010, World journal of hepatology.

[15]  J. Tonn,et al.  Presence of pluripotent CD133+ cells correlates with malignancy of gliomas , 2010, Molecular and Cellular Neuroscience.

[16]  X. Wang,et al.  EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. , 2009, Gastroenterology.

[17]  M. Israel,et al.  Cancer stem cells are enriched in the side population cells in a mouse model of glioma. , 2008, Cancer research.

[18]  Xiaofeng Yang,et al.  Identification of cancer stem-like cells in the C6 glioma cell line and the limitation of current identification methods , 2008, In Vitro Cellular & Developmental Biology - Animal.

[19]  K. Chan,et al.  Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations , 2008, Molecular Cancer Research.

[20]  S. Chiou,et al.  Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma , 2008, Clinical Cancer Research.

[21]  X. Bian,et al.  Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87. , 2008, Cancer letters.

[22]  Liang Tang,et al.  Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells. , 2008, Cancer research.

[23]  Wenjun Guo,et al.  The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.

[24]  X. Guan,et al.  CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway , 2008, Oncogene.

[25]  N. Iizuka,et al.  Decreased ID2 Promotes Metastatic Potentials of Hepatocellular Carcinoma by Altering Secretion of Vascular Endothelial Growth Factor , 2008, Clinical Cancer Research.

[26]  S. Fan,et al.  Significance of CD90+ cancer stem cells in human liver cancer. , 2008, Cancer cell.

[27]  Stephen Lam,et al.  Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. , 2007, Cancer research.

[28]  I. Ng,et al.  Identification and characterization of tumorigenic liver cancer stem/progenitor cells. , 2007, Gastroenterology.

[29]  Frank Pajonk,et al.  The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. , 2006, Journal of the National Cancer Institute.

[30]  Mark W. Dewhirst,et al.  Glioma stem cells promote radioresistance by preferential activation of the DNA damage response , 2006, Nature.

[31]  Irving L Weissman,et al.  Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. , 2006, Cancer research.

[32]  Tetsuhiro Chiba,et al.  Side population purified from hepatocellular carcinoma cells harbors cancer stem cell–like properties , 2006, Hepatology.

[33]  Yuri Kotliarov,et al.  Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. , 2006, Cancer cell.

[34]  M. Gottesman,et al.  Targeting multidrug resistance in cancer , 2006, Nature Reviews Drug Discovery.

[35]  K. Newman,et al.  Video-assisted thoracic surgery (VATS) for children with pulmonary metastases from osteosarcoma , 1996, Annals of Surgical Oncology.

[36]  R. Henkelman,et al.  Identification of human brain tumour initiating cells , 2004, Nature.

[37]  G. Chau,et al.  Long-term results of hepatic resection for hepatocellular carcinoma originating from the noncirrhotic liver. , 2004, Archives of surgery.

[38]  Dong-Hua Yang,et al.  Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. , 2003, Gene expression patterns : GEP.

[39]  P. Kuo,et al.  Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. , 2003, Carcinogenesis.

[40]  J. Nichols,et al.  Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells , 2003, Cell.

[41]  O. Coqueret,et al.  New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? , 2003, Trends in cell biology.

[42]  G. Semenza,et al.  HIF-1 and tumor progression: pathophysiology and therapeutics. , 2002, Trends in molecular medicine.

[43]  H. Jun,et al.  Recent advances in insulin gene therapy for type 1 diabetes. , 2002, Trends in molecular medicine.

[44]  M. Gottesman.  Mechanisms of cancer drug resistance. , 2002, Annual review of medicine.

[45]  Leila Mohammadi,et al.  BMC Cancer , 2001 .

[46]  S. Fan,et al.  Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma. , 2000, Annals of surgery.

[47]  K. Endo,et al.  Protein expression of CD44 (standard and variant isoforms) in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, p53 expression, and patient survival. , 2000, Journal of hepatology.

[48]  James M. Roberts,et al.  CDK inhibitors: positive and negative regulators of G1-phase progression. , 1999, Genes & development.

[49]  D. Woodfield.  Hepatocellular carcinoma. , 1986, The New Zealand medical journal.