Cervical implantation of intrathecal baclofen pump catheter in children with severe scoliosis.

OBJECT Intrathecal baclofen (ITB) pump catheter placement is traditionally performed through entry into the spinal sac at the lumbar spine. A minority of children with cerebral palsy have severe concomitant neuromuscular scoliosis. In these children, whether surgically treated or not, access to the intradural space via the lumbar spine may prove technically challenging. The authors report on a series of children in whom, for various reasons, an ITB catheter was implanted using a posterior cervical spine approach. METHODS The records of 20 children in whom a baclofen catheter had been placed were retrospectively reviewed to assess the demographic details, indications, and outcome of this procedure. RESULTS This approach was successful in all but one of the children in whom the procedure was abandoned given the presence of significant extradural scar tissue. Of the 20 children, 7 had previously undergone lumbar ITB catheter implantation, although the catheter was subsequently, iatrogenically transected during scoliosis surgery. Nine children had had corrective scoliosis surgery, and the fusion mass obviated access to the lumbar spinal sac. Four children had untreated scoliosis and corrective surgery was being contemplated. Complications included infection requiring explantation (2 patients), catheter migration (1 patient), intolerance to ITB (1 patient), and failure of implantation (1 patient). All patients who tolerated the ITB experienced improvement in spasticity. No complications were associated with the spinal level of catheter insertion. CONCLUSIONS Implantation of an ITB catheter via a cervical approach is safe and feasible and should be considered in children with severe corrected or uncorrected scoliosis, and thus avoiding the lumbar spinal sac.

[1]  A. Ferrari,et al.  Severe scoliosis in neurodevelopmental disabilities: clinical signs and therapeutic proposals. , 2010, European journal of physical and rehabilitation medicine.

[2]  M. Vloeberghs,et al.  Intrathecal baclofen therapy for spasticity of cerebral origin—does the position of the intrathecal catheter matter? , 2010, Child's Nervous System.

[3]  A. Scheinberg,et al.  Continuous intrathecal baclofen for children with spasticity and/or dystonia: Goal attainment and complications associated with treatment , 2009, Journal of paediatrics and child health.

[4]  S. Koop,et al.  Scoliosis in cerebral palsy , 2009, Developmental medicine and child neurology.

[5]  J. Becher,et al.  Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a randomised controlled trial. , 2009, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[6]  L. Lai,et al.  The Impact of Intrathecal Baclofen on the Natural History of Scoliosis in Cerebral Palsy , 2008, Journal of pediatric orthopedics.

[7]  D. Goodall,et al.  Rate of complications in scoliosis surgery – a systematic review of the Pub Med literature , 2008, Scoliosis.

[8]  G. Ginsburg,et al.  Progression of Scoliosis in Patients With Spastic Quadriplegia After the Insertion of an Intrathecal Baclofen Pump , 2007, Spine.

[9]  F. Miller,et al.  The Risk of Progression of Scoliosis in Cerebral Palsy Patients After Intrathecal Baclofen Therapy , 2007, Spine.

[10]  K. Woon,et al.  The role of intrathecal baclofen in the management of primary and secondary dystonia in children , 2007, British journal of neurosurgery.

[11]  A. L. Albright,et al.  Best-practice surgical techniques for intrathecal baclofen therapy. , 2006, Journal of neurosurgery.

[12]  B. Iskandar,et al.  Placement of baclofen pumps through the foramen magnum and upper cervical spine , 2006, Child’s Nervous System.

[13]  M. Vloeberghs,et al.  Intrathecal baclofen in the management of spasticity due to cerebral palsy , 2005, Pediatric rehabilitation.

[14]  L. Krach,et al.  Intrathecal Baclofen for Management of Spastic Cerebral Palsy: Multicenter Trial , 2000, Journal of child neurology.

[15]  J. Janosky,et al.  Continuous intrathecal baclofen infusion for spasticity of cerebral origin. , 1993, JAMA.

[16]  M. Walker,et al.  Posterior cervical approach for intrathecal baclofen pump insertion in children with previous spinal fusions. Technical note. , 2005, Journal of neurosurgery.