Snail regulated by PKC/GSK-3β pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells

[1]  Shun-Fa Yang,et al.  Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy. , 2014, Clinica chimica acta; international journal of clinical chemistry.

[2]  L. Sun,et al.  Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma , 2013, British Journal of Cancer.

[3]  Tsung-Ying Yang,et al.  Luteolin attenuates TGF-β1-induced epithelial-mesenchymal transition of lung cancer cells by interfering in the PI3K/Akt-NF-κB-Snail pathway. , 2013, Life sciences.

[4]  B. Zhou,et al.  The Role of Snail in EMT and Tumorigenesis. , 2013, Current cancer drug targets.

[5]  Eun-Kyoung Breuer,et al.  TACC3 Is Essential for EGF-Mediated EMT in Cervical Cancer , 2013, PloS one.

[6]  Jun Du,et al.  Nodal promotes aggressive phenotype via Snail-mediated epithelial-mesenchymal transition in murine melanoma. , 2013, Cancer letters.

[7]  Ge Zhang,et al.  Epithelial–Mesenchymal Transition (EMT) Induced by TNF-α Requires AKT/GSK-3β-Mediated Stabilization of Snail in Colorectal Cancer , 2013, PloS one.

[8]  V. Odero-Marah,et al.  The role of Snail in prostate cancer , 2012, Cell adhesion & migration.

[9]  Jun Yao,et al.  G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer. , 2012, The Journal of clinical investigation.

[10]  M. Roizen,et al.  Hallmarks of Cancer: The Next Generation , 2012 .

[11]  G. Giovinazzo,et al.  Resveratrol inhibits the epidermal growth factor-induced epithelial mesenchymal transition in MCF-7 cells. , 2011, Cancer letters.

[12]  Maoyu Li,et al.  Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT‐like phenotype change and MMP‐9‐mediated degradation of E‐cadherin , 2011, Journal of cellular biochemistry.

[13]  S. Thomson,et al.  Inducible expression of TGFβ, Snail and Zeb1 recapitulates EMT in vitro and in vivo in a NSCLC model , 2011, Clinical & Experimental Metastasis.

[14]  I. Leav,et al.  ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. , 2010, Cancer cell.

[15]  B. Zhou,et al.  Snail: More than EMT. , 2010, Cell adhesion & migration.

[16]  M. Brentani,et al.  Concomitant expression of epithelial-mesenchymal transition biomarkers in breast ductal carcinoma: association with progression. , 2009, Oncology reports.

[17]  Y. Kang,et al.  Epidermal growth factor signalling and bone metastasis , 2009, British Journal of Cancer.

[18]  Erik W Thompson,et al.  Epithelial to mesenchymal transition and breast cancer , 2009, Breast Cancer Research.

[19]  W. Hsu,et al.  Prognostic significance of hypoxia-inducible factor-1α, TWIST1 and Snail expression in resectable non-small cell lung cancer , 2009, Thorax.

[20]  E. Neilson,et al.  Biomarkers for epithelial-mesenchymal transitions. , 2009, The Journal of clinical investigation.

[21]  Suimin Qiu,et al.  Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. , 2009, Cancer cell.

[22]  A. Cheung,et al.  p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells. , 2008, Cancer research.

[23]  Ming-Jer Tang,et al.  Epithelial-Mesenchymal Transition in Cervical Cancer: Correlation with Tumor Progression, Epidermal Growth Factor Receptor Overexpression, and Snail Up-Regulation , 2008, Clinical Cancer Research.

[24]  A. Newton,et al.  The life and death of protein kinase C. , 2008, Current drug targets.

[25]  Sheng-Chieh Hsu,et al.  Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression. , 2007, Cancer research.

[26]  Héctor Peinado,et al.  Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? , 2007, Nature Reviews Cancer.

[27]  A. Cano,et al.  Snail silencing effectively suppresses tumour growth and invasiveness , 2007, Oncogene.

[28]  Yarong Wang,et al.  Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. , 2007, Cancer research.

[29]  Soo-Hyun Park,et al.  Effect of EGF on [3H]‐thymidine incorporation and cell cycle regulatory proteins in primary cultured chicken hepatocytes: Involvement of Ca2+/PKC and MAPKs , 2006, Journal of cellular biochemistry.

[30]  G. Christofori New signals from the invasive front , 2006, Nature.

[31]  Erik Sahai,et al.  Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. , 2005, Cancer research.

[32]  Jubilee R. Stewart,et al.  Protein kinase C-α mediates epidermal growth factor receptor transactivation in human prostate cancer cells , 2005, Molecular Cancer Therapeutics.

[33]  G. Berx,et al.  Unraveling signalling cascades for the Snail family of transcription factors. , 2005, Cellular signalling.

[34]  M. Hung,et al.  Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition , 2004, Nature Cell Biology.

[35]  S. Dedhar,et al.  Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells , 2004, Oncogene.

[36]  Kenji Tada,et al.  Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme. , 2003, Cancer research.

[37]  E. Neilson,et al.  The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis. , 2003, Cancer research.

[38]  B. Doble,et al.  GSK-3: tricks of the trade for a multi-tasking kinase , 2003, Journal of Cell Science.

[39]  M. Waltham,et al.  Epidermal Growth Factor-Induced Epithelio-Mesenchymal Transition in Human Breast Carcinoma Cells , 2003, Laboratory Investigation.

[40]  M. Nieto,et al.  The snail superfamily of zinc-finger transcription factors , 2002, Nature Reviews Molecular Cell Biology.

[41]  Y. Yarden The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. , 2001, European journal of cancer.

[42]  John Mendelsohn,et al.  The EGF receptor family as targets for cancer therapy , 2000, Oncogene.

[43]  G. Mills,et al.  Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[44]  J. Burke,et al.  Epidermal growth factor activates protein kinase C in the human endometrial cancer cell line HEC-1-A. , 1997, Gynecologic oncology.

[45]  P. Pelicci,et al.  The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-Receptor , 1997, Oncogene.

[46]  P. Cohen,et al.  Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B , 1995, Nature.

[47]  N. Normanno,et al.  Epidermal growth factor-related peptides and their receptors in human malignancies. , 1995, Critical reviews in oncology/hematology.

[48]  P. Cohen,et al.  The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells. , 1994, The Biochemical journal.

[49]  J. Woodgett,et al.  Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes. , 1992, The Journal of biological chemistry.

[50]  K. Harshman,et al.  Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. , 1990, Nucleic acids research.