Prevalence and Predictors of Immunological Treatment Failure among HIV Infected Adults on the First-line Antiretroviral Therapy in Mbeya Region , Tanzania

Mathews Journal of HIV/AIDS Prevalence and Predictors of Immunological Treatment Failure among HIV Infected Adults on the First-line Antiretroviral Therapy in Mbeya Region, Tanzania Callist L. Chomboko1, Rogatus M. Kabyemera2, Benson R. Kidenya3, Erasmus Kamugisha3* 1School of Public Health, Catholic University of Health and Allied Sciences 2Department of Paediatrics and Child Health, Bugando Medical Centre 3Department of Biochemistry, Catholic University of Health and Allied Sciences Corresponding Author: Erasmus Kamugisha, Department of Biochemistry, Catholic University of Health and Allied Sciences, P.O Box 1464, Mwanza, Tanzania, Email: erasmuskamugisha@yahoo.com

[1]  Takura Matare Factors associated with Human Immunodeficiency Virus first line treatment failure in Zvishavane District, Midlands Province, 2014 , 2016 .

[2]  D. Gunda,et al.  Magnitude and correlates of moderate to severe anemia among adult HIV patients receiving first line HAART in Northwestern Tanzania: a cross sectional clinic based study , 2016, The Pan African medical journal.

[3]  A. Kumie,et al.  Assessment of the magnitude and associated factors of immunological failure among adult and adolescent HIV-infected patients in St. Luke and Tulubolo Hospital, Oromia Region, Ethiopia , 2015, The Pan African medical journal.

[4]  K. Yirdaw,et al.  Prevalence and Predictors of Immunological Failure among HIV Patients on HAART in Southern Ethiopia , 2015, PloS one.

[5]  D. Mmbando,et al.  Immunological failure of first-line and switch to second-line antiretroviral therapy among HIV-infected persons in Tanzania: analysis of routinely collected national data , 2015, Tropical medicine & international health : TM & IH.

[6]  D. Gunda,et al.  Prevalence and predictors of Immunological failure among HIV-infected adults on HAART in Northwestern Tanzania: A cross sectional study , 2015 .

[7]  W. Teshome,et al.  Predictors of Immunological Failure of Antiretroviral Therapy among HIV Infected Patients in Ethiopia: A Matched Case-Control Study , 2014, PloS one.

[8]  A. Kapesa,et al.  Determinants of immunological failure among clients on the first line treatment with highly active antiretroviral drugs in Dar es Salaam, Tanzania , 2014 .

[9]  N. Taveira,et al.  Predictors of Attrition and Immunological Failure in HIV-1 Patients on Highly Active Antiretroviral Therapy from Different Healthcare Settings in Mozambique , 2013, PloS one.

[10]  W. Blattner,et al.  Immuno-virologic outcomes and immuno-virologic discordance among adults alive and on anti-retroviral therapy at 12 months in Nigeria , 2013, BMC Infectious Diseases.

[11]  P. Mtesigwa Response to antiretroviral therapy in HIV - infected patients attending care and treatment centre in Dar-es-salaam, Tanzania , 2013 .

[12]  A. Siika,et al.  Factors Associated with First-Line Antiretroviral Therapy Failure amongst HIV-Infected African Patients: A Case-Control Study , 2012 .

[13]  D. Pillay,et al.  Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis , 2012, The Lancet.

[14]  M. Hernán,et al.  Rates and Predictors of Failure of First-line Antiretroviral Therapy and Switch to Second-line ART in South Africa , 2012, Journal of acquired immune deficiency syndromes.

[15]  Beth Chaplin,et al.  Immunologic criteria are poor predictors of virologic outcome: implications for HIV treatment monitoring in resource-limited settings. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[16]  N. Ford,et al.  Life Expectancy of Persons Receiving Combination Antiretroviral Therapy in Low-Income Countries: A Cohort Analysis From Uganda , 2011, Annals of Internal Medicine.

[17]  D. Katzenstein,et al.  Adherence to Drug-Refill Is a Useful Early Warning Indicator of Virologic and Immunologic Failure among HIV Patients on First-Line ART in South Africa , 2011, PloS one.

[18]  H. Bang,et al.  Early versus standard antiretroviral therapy for HIV-infected adults in Haiti. , 2010, The New England journal of medicine.

[19]  M. Egger,et al.  Mortality after failure of antiretroviral therapy in sub‐Saharan Africa , 2010, Tropical medicine & international health : TM & IH.

[20]  S. Mshana,et al.  Prevalence of immunological failure and durability of first line antiretroviral therapy at Bugando Hospital Mwanza, Tanzania , 2010 .

[21]  T. Quinn,et al.  Failure of immunologic criteria to appropriately identify antiretroviral treatment failure in Uganda , 2009, AIDS.

[22]  A. Geretti Epidemiology of antiretroviral drug resistance in drug-naïve persons , 2007, Current opinion in infectious diseases.

[23]  T. Flanigan,et al.  Reasons for Modification of Generic Highly Active Antiretroviral Therapeutic Regimens Among Patients in Southern India , 2006, Journal of acquired immune deficiency syndromes.

[24]  A. Mocroft,et al.  Predictors of immunological failure after initial response to highly active antiretroviral therapy in HIV-1-infected adults: a EuroSIDA study. , 2004, The Journal of infectious diseases.

[25]  M. Lederman,et al.  Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function , 2001, AIDS.

[26]  D. Neau,et al.  Prognostic Factors of Combined Viral Load and CD4+ Cell Count Responses Under Triple Antiretroviral Therapy, Aquitaine Cohort, 1996‐1998 , 2001, Journal of acquired immune deficiency syndromes.