Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly
暂无分享,去创建一个
[1] A. Clerk,et al. Small guanine nucleotide-binding proteins and myocardial hypertrophy. , 2000, Circulation research.
[2] J. C. Ayoob,et al. Assembly of myofibrils in cardiac muscle cells. , 2000, Advances in experimental medicine and biology.
[3] A. Thorburn,et al. MAP kinase‐ and Rho‐dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells , 1997, The EMBO journal.
[4] C. Coulson,et al. Molecular Structure , 1973, Nature.
[5] P. Cohen,et al. Stress-activated Protein Kinase-2/p38 and a Rapamycin-sensitive Pathway Are Required for C2C12 Myogenesis* , 1999, The Journal of Biological Chemistry.
[6] A. Rhoads,et al. Sequence motifs for calmodulin recognition , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] K. Wang,et al. Titin: major myofibrillar components of striated muscle. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[8] M. Gautel,et al. Control of sarcomeric assembly: the flow of information on titin. , 1999, Reviews of physiology, biochemistry and pharmacology.
[9] J. Devereux,et al. A comprehensive set of sequence analysis programs for the VAX , 1984, Nucleic Acids Res..
[10] Y. Zheng,et al. The Dbl family of oncogenes. , 1996, Current opinion in cell biology.
[11] A. Pastore,et al. Immunoglobulin‐type domains of titin are stabilized by amino‐terminal extension , 1994, FEBS letters.
[12] H. Stedman,et al. Human Skeletal Muscle Nebulin Sequence Encodes a Blueprint for Thin Filament Architecture , 1996, The Journal of Biological Chemistry.
[13] Anirvan Ghosh,et al. Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF , 1995, Nature.
[14] C. Lehner,et al. A new 185,000-dalton skeletal muscle protein detected by monoclonal antibodies , 1984, The Journal of cell biology.
[15] A. Debant,et al. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[16] B. Schäfer,et al. Dral Is a P53-Responsive Gene Whose Four and a Half Lim Domain Protein Product Induces Apoptosis , 2000, The Journal of cell biology.
[17] H. Jörnvall,et al. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. , 1989, The Journal of biological chemistry.
[18] S. Aaronson,et al. Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product , 1991, Nature.
[19] International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome , 2001, Nature.
[20] Paul Young,et al. Structural basis for activation of the titin kinase domain during myofibrillogenesis , 1998, Nature.
[21] K. R. Weiss,et al. Autophosphorylation of molluscan twitchin and interaction of its kinase domain with calcium/calmodulin. , 1994, The Journal of biological chemistry.
[22] J. Trinick. Cytoskeleton: Titin as a scaffold and spring , 1996, Current Biology.
[23] M. Gautel,et al. Integration of titin into the sarcomeres of cultured differentiating human skeletal muscle cells. , 1996, European journal of cell biology.
[24] A. Hattori,et al. Detection of giant myofibrillar proteins connectin and nebulin by electrophoresis in 2% polyacrylamide slab gels strengthened with agarose. , 1995, Analytical biochemistry.
[25] M. Borodovsky,et al. The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains , 1996, The Journal of cell biology.
[26] Keith Dudley. Short protocols in molecular biology , 1990 .
[27] S. Labeit,et al. Towards a molecular understanding of titin. , 1992, The EMBO journal.
[28] S. Fullerton,et al. Camstatins Are Peptide Antagonists of Calmodulin Based Upon a Conserved Structural Motif in PEP-19, Neurogranin, and Neuromodulin* , 1996, The Journal of Biological Chemistry.
[29] Jiahuai Han,et al. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. , 2000, Genes & development.
[30] J Ross,et al. Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family* , 1998, The Journal of Biological Chemistry.
[31] B. Kolmerer,et al. The complete primary structure of human nebulin and its correlation to muscle structure. , 1995, Journal of molecular biology.
[32] J. Thompson,et al. Using CLUSTAL for multiple sequence alignments. , 1996, Methods in enzymology.
[33] A. Pastore,et al. Immunoglobulin-like modules from titin I-band: extensible components of muscle elasticity. , 1996, Structure.
[34] K. Pelin,et al. Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. , 2001, Journal of molecular biology.
[35] Toren Finkel. Myocyte hypertrophy: the long and winding RhoA'd. , 1999, The Journal of clinical investigation.
[36] M. Gautel,et al. A molecular map of titin/connectin elasticity reveals two different mechanisms acting in series , 1996, FEBS letters.
[37] J. Thompson,et al. The PH domain: a common piece in the structural patchwork of signalling proteins. , 1993, Trends in biochemical sciences.
[38] Siegfried Labeit,et al. Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity , 1995, Science.
[39] C. Gregorio,et al. Muscle assembly: a titanic achievement? , 1999, Current opinion in cell biology.
[40] Xin-Yun Huang,et al. Structural Basis for Relief of Autoinhibition of the Dbl Homology Domain of Proto-Oncogene Vav by Tyrosine Phosphorylation , 2000, Cell.
[41] K. Weber,et al. The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line , 1988, The Journal of cell biology.
[42] U. K. Laemmli,et al. Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.
[43] M. Gautel,et al. Titin domain patterns correlate with the axial disposition of myosin at the end of the thick filament. , 1996, Journal of molecular biology.
[44] B. Kolmerer,et al. Genomic organization of M line titin and its tissue-specific expression in two distinct isoforms. , 1996, Journal of molecular biology.
[45] R. Waterston,et al. Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans , 1989, Nature.
[46] K. Rossman,et al. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1 , 2000, Nature.
[47] K. Chien,et al. Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen. , 1988, The Journal of biological chemistry.
[48] J C Perriard,et al. Myofibrillogenesis in the developing chicken heart: assembly of Z-disk, M-line and the thick filaments. , 1999, Journal of cell science.
[49] M. Kozak. The scanning model for translation: an update , 1989, The Journal of cell biology.
[50] M. Gautel,et al. The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers. , 1996, Journal of cell science.
[51] A. Hall,et al. Rho GTPases and their effector proteins. , 2000, The Biochemical journal.
[52] J. Perriard,et al. The intracompartmental sorting of myosin alkali light chain isoproteins reflects the sequence of developmental expression as determined by double epitope-tagging competition. , 1996, Journal of cell science.
[53] J. Trinick,et al. Does titin regulate the length of muscle thick filaments? , 1989, Journal of molecular biology.
[54] M. Gautel,et al. A molecular map of the interactions between titin and myosin-binding protein C. Implications for sarcomeric assembly in familial hypertrophic cardiomyopathy. , 1996, European journal of biochemistry.
[55] A. Pastore,et al. Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set. , 1995, Structure.
[56] E. Golemis,et al. ArgBP2, a Multiple Src Homology 3 Domain-containing, Arg/Abl-interacting Protein, Is Phosphorylated in v-Abl-transformed Cells and Localized in Stress Fibers and Cardiocyte Z-disks* , 1997, The Journal of Biological Chemistry.
[57] A. Ridley,et al. Rho family proteins and regulation of the actin cytoskeleton. , 1999, Progress in molecular and subcellular biology.
[58] M. Gautel,et al. A functional knock-out of titin results in defective myofibril assembly. , 2000, Journal of cell science.
[59] H. Yajima,et al. A 11.5-kb 5'-terminal cDNA sequence of chicken breast muscle connectin/titin reveals its Z line binding region. , 1996, Biochemical and biophysical research communications.
[60] K. Chien. Genomic circuits and the integrative biology of cardiac diseases , 2000, Nature.
[61] Zhenguo Wu,et al. p38 and Extracellular Signal-Regulated Kinases Regulate the Myogenic Program at Multiple Steps , 2000, Molecular and Cellular Biology.
[62] K Weber,et al. Molecular structure of the sarcomeric M band: mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin , 1997, The EMBO journal.
[63] W. Linke,et al. Towards a molecular understanding of the elasticity of titin. , 1996, Journal of molecular biology.
[64] M. Gautel. The super-repeats of titin/connectin and their interactions: glimpses at sarcomeric assembly. , 1996, Advances in biophysics.
[65] E. Bengal,et al. p38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation , 1999, The Journal of Biological Chemistry.
[66] J. Trinick,et al. Titin: a molecular control freak. , 1999, Trends in cell biology.
[67] M. Gautel,et al. Two immunoglobulin‐like domains of the Z‐disc portion of titin interact in a conformation‐dependent way with telethonin , 1998, FEBS letters.
[68] M. Nilges,et al. The PH superfold: a structural scaffold for multiple functions. , 1999, Trends in biochemical sciences.
[69] K. Maruyama,et al. Connectin, an elastic protein from myofibrils. , 1976, Journal of biochemistry.
[70] P. F. van der Ven,et al. Assembly of titin, myomesin and M-protein into the sarcomeric M band in differentiating human skeletal muscle cells in vitro. , 1997, Cell structure and function.
[71] M. Gautel,et al. Molecular structure of the sarcomeric Z‐disk: two types of titin interactions lead to an asymmetrical sorting of α‐actinin , 1998, The EMBO journal.
[72] J. Whitfield,et al. Ca2+–calmodulin and protein kinase Cs: a hypothetical synthesis of their conflicting convergences on shared substrate domains , 1999, Trends in Neurosciences.