论文信息 - Clinical Epidemiology: How to Do Clinical Practice Research

Clinical Epidemiology: How to Do Clinical Practice Research

PART ONE: Performing Clinical Research * Forming Research Questions... 3 * Conducting Systematic Reviews... 15 * Finding Information About the Burden of Disease... 49 * An Introduction to Performing Therapeutic Trials... 59 * The Tactics of Performing Therapeutic Trials... 66 * The Principles Behind the Tactics of Performing Therapeutic Trials... 173 * Testing Quality Improvement Interventions... 244 * Evaluating Diagnostic Tests... 273 * Determining Prognosis and Creating Clinical Decision Rules... 323 * Assessing Claims of Causation... 356 * Generating Outcome Measurements, Especially for Quality of Life... 388 PART TWO: Becoming a Clinical Researcher * Becoming a Successful Clinician-Investigator... 415 * Preparing a Research Protocol to Improve its Chances for Success... 429 * Online Data Collection... 440 * Analyzing Data... 446 * Preparing Reports for Publication and Responding to Reviewers' Comments... 461 * Dealing with the Media... 474 Index... 487

[1] B. Freedman. Equipoise and the ethics of clinical research. , 1987, The New England journal of medicine.

[2] R B Haynes,et al. Patient compliance and the conduct and interpretation of therapeutic trials. , 1987, Controlled clinical trials.

[3] Douglas G. Altman,et al. Practical statistics for medical research , 1990 .

[4] George W. Cobb,et al. Introductory Textbooks: A Framework for Evaluation , 1987 .

[5] W. Inman. Monitoring for drug safety , 1981 .

[6] D. Sackett,et al. IMPROVEMENT OF MEDICATION COMPLIANCE IN UNCONTROLLED HYPERTENSION , 1976, The Lancet.

[7] F. Mosteller,et al. Costs, Risks, and Benefits of Surgery , 1977 .

[8] A. Hill,et al. Suspended judgment. Memories of the British Streptomycin Trial in Tuberculosis. The first randomized clinical trial. , 1990, Controlled clinical trials.

[9] D. Sackett,et al. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. , 1991, The New England journal of medicine.

[10] A. Detsky,et al. When was a "negative" clinical trial big enough? How many patients you needed depends on what you found. , 1985, Archives of internal medicine.