Ultra-High Mass Resolution MALDI Imaging Mass Spectrometry of Proteins and Metabolites in a Mouse Model of Glioblastoma

[1]  F. Sotgia,et al.  Cancer metabolism: a therapeutic perspective , 2017, Nature Reviews Clinical Oncology.

[2]  Laura M. Cole,et al.  Imaging Mass Spectrometry , 2017, Methods in Molecular Biology.

[3]  L. McDonnell,et al.  Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function. , 2016, Neuro-Oncology.

[4]  L. McDonnell,et al.  Set of Novel Automated Quantitative Microproteomics Protocols for Small Sample Amounts and Its Application to Kidney Tissue Substructures. , 2016, Journal of proteome research.

[5]  L. McDonnell,et al.  Funnel‐freezing versus heat‐stabilization for the visualization of metabolites by mass spectrometry imaging in a mouse stroke model , 2016, Proteomics.

[6]  Eric P Skaar,et al.  Next‐generation technologies for spatial proteomics: Integrating ultra‐high speed MALDI‐TOF and high mass resolution MALDI FTICR imaging mass spectrometry for protein analysis , 2016, Proteomics.

[7]  A. Feuchtinger,et al.  In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry , 2016, Proteomics.

[8]  L. McDonnell,et al.  Mass spectrometry imaging of amino neurotransmitters: a comparison of derivatization methods and application in mouse brain tissue , 2016, Metabolomics.

[9]  Tyler E. Miller,et al.  An epigenetic gateway to brain tumor cell identity , 2015, Nature Neuroscience.

[10]  Eric P Skaar,et al.  MALDI FTICR IMS of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data , 2015, Journal of The American Society for Mass Spectrometry.

[11]  M. Belting,et al.  Global Profiling of Metabolic Adaptation to Hypoxic Stress in Human Glioblastoma Cells , 2015, PloS one.

[12]  J. Denu,et al.  Metabolic regulation of histone post-translational modifications. , 2015, ACS chemical biology.

[13]  Bram Heijs,et al.  Comprehensive analysis of the mouse brain proteome sampled in mass spectrometry imaging. , 2015, Analytical chemistry.

[14]  J. Yates,et al.  Isobaric Labeling-Based Relative Quantification in Shotgun Proteomics , 2014, Journal of proteome research.

[15]  Y. Hannun,et al.  On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging , 2014, Analytical chemistry.

[16]  C. Fiorentini,et al.  The bacterial protein toxin, cytotoxic necrotizing factor 1 (CNF1) provides long-term survival in a murine glioma model , 2014, BMC Cancer.

[17]  M. Suematsu,et al.  Visualization and quantification of cerebral metabolic fluxes of glucose in awake mice , 2014, Proteomics.

[18]  Garry L Corthals,et al.  MSiMass list: a public database of identifications for protein MALDI MS imaging. , 2014, Journal of proteome research.

[19]  G. Reifenberger,et al.  Thymosin β 4 gene silencing decreases stemness and invasiveness in glioblastoma. , 2014, Brain : a journal of neurology.

[20]  T. Seyfried,et al.  Cancer as a metabolic disease: implications for novel therapeutics , 2013, Carcinogenesis.

[21]  J. Meier Metabolic mechanisms of epigenetic regulation. , 2013, ACS chemical biology.

[22]  Theodore Alexandrov,et al.  Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas , 2013, Hepatology.

[23]  B. Kamińska,et al.  Is Glioblastoma an Epigenetic Malignancy? , 2013, Cancers.

[24]  W. Mason,et al.  Emerging Biomarkers in Glioblastoma , 2013, Cancers.

[25]  Benjamin A Garcia,et al.  Proteomic characterization of novel histone post-translational modifications , 2013, Epigenetics & Chromatin.

[26]  Anushya Muruganujan,et al.  Large-scale gene function analysis with the PANTHER classification system , 2013, Nature Protocols.

[27]  Bernhard Kuster,et al.  Comprehensive Identification of Proteins from MALDI Imaging* , 2013, Molecular & Cellular Proteomics.

[28]  M. Fischer,et al.  Influence of various on-tissue washing procedures on the entire protein quantity and the quality of matrix-assisted laser desorption/ionization spectra. , 2013, Rapid Communications in Mass Spectrometry.

[29]  John C. Price,et al.  Mass spectrometry imaging for in situ kinetic histochemistry , 2013, Scientific Reports.

[30]  S. Nicolardi,et al.  Identification of new apolipoprotein-CIII glycoforms with ultrahigh resolution MALDI-FTICR mass spectrometry of human sera. , 2013, Journal of proteome research.

[31]  Philippe Dessen,et al.  Atlas of Genetics and Cytogenetics in Oncology and Haematology in 2013 , 2012, Nucleic Acids Res..

[32]  Steven Eschrich,et al.  Molecular and Cellular Pathobiology The Metabolomic Signature of Malignant Glioma Re fl ects Accelerated Anabolic Metabolism , 2012 .

[33]  S. Rauser,et al.  S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI Imaging , 2012, Journal of Molecular Medicine.

[34]  Richard M Caprioli,et al.  Protein signatures for survival and recurrence in metastatic melanoma. , 2011, Journal of proteomics.

[35]  S. Marie,et al.  Metabolism and Brain Cancer , 2011, Clinics.

[36]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[37]  S. Gygi,et al.  ms3 eliminates ratio distortion in isobaric multiplexed quantitative , 2011 .

[38]  Liam A. McDonnell,et al.  Imaging mass spectrometry data reduction: Automated feature identification and extraction , 2010, Journal of the American Society for Mass Spectrometry.

[39]  A. Guha,et al.  Targeting Metabolic Remodeling in Glioblastoma Multiforme , 2010, Oncotarget.

[40]  L. McDonnell,et al.  Peptide and protein imaging mass spectrometry in cancer research. , 2010, Journal of proteomics.

[41]  M. Ohmura,et al.  Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry. , 2010, Antioxidants & redox signaling.

[42]  H. Shim,et al.  Molecular proteomics imaging of tumor interfaces by mass spectrometry. , 2010, Journal of proteome research.

[43]  D. Wishart Applications of Metabolomics in Drug Discovery and Development , 2008, Drugs in R&D.

[44]  C. Allis,et al.  Extraction, purification and analysis of histones , 2007, Nature Protocols.

[45]  J. Xu,et al.  Ribosomal proteins and colorectal cancer. , 2007, Current genomics.

[46]  P. Chaurand,et al.  Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis. , 2007, International journal of mass spectrometry.

[47]  G. Collins The next generation. , 2006, Scientific American.

[48]  Ioannis Panagopoulos,et al.  Atlas of Genetics and Cytogenetics in Oncology and Haematology , 2005 .

[49]  M. Mori,et al.  Ubiquitin fusion proteins are overexpressed in colon cancer but not in gastric cancer. , 1995, Biochimica et biophysica acta.

[50]  C. Williamson,et al.  Therapeutic perspective. , 1951, California medicine.