A 1024-Channel GFET 10-bit 5-kHz 36-μW Read-Out Integrated Circuit for Brain JLECoG

This paper presents a 1024-channel ROIC for brain massive digital μECoG, which uses liquid-gate GFETs as active sensors. The proposed channel multiplexing technique at the recording array level allows strong reductions of the sensor-to-circuit connectivity, low-cost hybrid integration and low-power operation. A mixed-signal ROIC architecture and CMOS circuit solutions are introduced to compensate for GFET mismatching and for the preamplifier noise figure loss when upscaling the number of recording sites. The 1024-channel 10-bit 5-kHz 36-μ$W$ single-chip design is currently being integrated in 0.18-μm CMOS technology and post-layout simulation results are reported.

[1]  W. Liu,et al.  A 128-Channel 6 mW Wireless Neural Recording IC With Spike Feature Extraction and UWB Transmitter , 2009, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[2]  Maria V. Sanchez-Vives,et al.  Flexible Graphene Solution‐Gated Field‐Effect Transistors: Efficient Transducers for Micro‐Electrocorticography , 2018 .

[3]  Srinjoy Mitra,et al.  A Neural Probe With Up to 966 Electrodes and Up to 384 Configurable Channels in 0.13 $\mu$m SOI CMOS , 2017, IEEE Transactions on Biomedical Circuits and Systems.

[4]  Francisco Serra-Graells,et al.  Variable-Mirror Amplifier: A New Family of Process-Independent Class-AB Single-Stage OTAs for Low-Power SC Circuits , 2016, IEEE Transactions on Circuits and Systems I: Regular Papers.

[5]  Refet Firat Yazicioglu,et al.  Time Multiplexed Active Neural Probe with 1356 Parallel Recording Sites , 2017, 2016 46th European Solid-State Device Research Conference (ESSDERC).

[6]  Gian Nicola Angotzi,et al.  A Synchronous Neural Recording Platform for Multiple High-Resolution CMOS Probes and Passive Electrode Arrays , 2018, IEEE Transactions on Biomedical Circuits and Systems.

[7]  E. Musk An Integrated Brain-Machine Interface Platform With Thousands of Channels , 2019, bioRxiv.

[8]  Vijay Viswam,et al.  22.8 Multi-functional microelectrode array system featuring 59,760 electrodes, 2048 electrophysiology channels, impedance and neurotransmitter measurement units , 2016, 2016 IEEE International Solid-State Circuits Conference (ISSCC).

[9]  Yiannos Manoli,et al.  Fully Immersible Subcortical Neural Probes With Modular Architecture and a Delta-Sigma ADC Integrated Under Each Electrode for Parallel Readout of 144 Recording Sites , 2018, IEEE Journal of Solid-State Circuits.