Iterative read mapping and assembly allows the use of a more distant reference in metagenome assembly

[1] B.E. Dutilh, M.A. Huynen and M. Strous (2009), "Increasing the coverage of a metapopulation consensus genome by iterative read mapping and assembly", Bioinformatics 25: 2878-2881. [2] K.F. Ettwig*, M.K. Butler*, D. Le Paslier, E. Pelletier, S. Mangenot, M.M.M. Kuypers, F. Schreiber, B.E. Dutilh, J. Zedelius, D. de Beer, J. Gloerich, H.J.C.T. Wessels, T.A. van Alen, F. Luesken, M.L. Wu, K.T. van de Pas-Schoonen, H.J.M. Op den Camp, E.M. Janssen-Megens, K.-J. Francoijs, H. Stunnenberg, J. Weissenbach, M.S.M. Jetten and M. Strous (2010), "Nitrite-driven anaerobic methane oxidation by oxygenic bacteria", Nature 464: 543-548. * Authors contributed equally. The number of mapped reads increases, the assembly converges, and the assembly diverges from the original reference with iterations. Results

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