Multi-Dose-Route, Multi-Species Pharmacokinetic Models for Manganese and Their Use in Risk Assessment
暂无分享,去创建一个
Harvey J Clewell | Melvin E Andersen | Andy Nong | David C Dorman | M. Andersen | H. Clewell | D. Dorman | A. Nong | Michael D. Taylor | Michael D Taylor
[1] A Beuter,et al. Manganese neurotoxicity, a continuum of dysfunction: results from a community based study. , 1999, Neurotoxicology.
[2] D. Lison,et al. Prospective study on the reversibility of neurobehavioral effects in workers exposed to manganese dioxide. , 1999, Neurotoxicology.
[3] G. Wood,et al. RISK ASSESSMENT FOR THE COMBUSTION PRODUCTS OF METHYLCYCLOPENTADIENYL MANGANESE TRICARBONYL (MMT) IN GASOLINE , 1999 .
[4] B. Asgharian,et al. A multiple-path model of particle deposition in the rat lung. , 1995, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[5] R. Cattley,et al. Manganese-induced developmental neurotoxicity in the CD rat: is oxidative damage a mechanism of action? , 1999, Neurotoxicology.
[6] Melvin E Andersen,et al. Dose-dependent transitions in mechanisms of toxicity: case studies. , 2004, Toxicology and applied pharmacology.
[7] M. Andersen,et al. Pharmacokinetic Modeling of Manganese. II. Hepatic Processing After Ingestion and Inhalation , 2007, Journal of toxicology and environmental health. Part A.
[8] L. Hurley. Teratogenic aspects of manganese, zinc, and copper nutrition. , 1981, Physiological reviews.
[9] M. Kubota,et al. Whole-blood manganese levels and brain manganese accumulation in children receiving long-term home parenteral nutrition , 2003, Pediatric Surgery International.
[10] N Makris,et al. Possible health effects of high manganese concentration in drinking water. , 1989, Archives of environmental health.
[11] Brian A Wong,et al. Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[12] R. Butterworth,et al. BIOACCUMULATION AND LOCOMOTOR EFFECT OF MANGANESE DUST IN RATS , 2001, Inhalation toxicology.
[13] J. Mahoney,et al. Studies on manganese. 3. The biological half-life of radiomanganese in man and factors which affect this half-life. , 1968, The Journal of clinical investigation.
[14] D Stanescu,et al. Epidemiological survey among workers exposed to manganese: effects on lung, central nervous system, and some biological indices. , 1987, American journal of industrial medicine.
[15] P. Gass,et al. Hypoglycemia-Elicited Immediate Early Gene Expression in Neurons and Glia of the Hippocampus: Novel Patterns of FOS, JUN, and KROX Expression following Excitotoxic Injury , 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[16] Michael Jerrett,et al. A study of the relationships between Parkinson's disease and markers of traffic-derived and environmental manganese air pollution in two Canadian cities. , 2007, Environmental research.
[17] D. Dorman,et al. Sub-chronic inhalation of high concentrations of manganese sulfate induces lower airway pathology in rhesus monkeys , 2005, Respiratory research.
[18] G. L’espérance,et al. Physical and Chemical Characterization of Mn Phosphate/Sulfate Mixture Used in an Inhalation Toxicology Study , 2004, Inhalation toxicology.
[19] D B Calne,et al. Manganese neurotoxicity: a review of clinical features, imaging and pathology. , 1999, Neurotoxicology.
[20] D. Dorman,et al. Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.
[21] A. Barbeau,et al. Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). , 1984, Neurotoxicology.
[22] O R Moss,et al. Pharmacokinetics of inhaled manganese phosphate in male Sprague-Dawley rats following subacute (14-day) exposure. , 2000, Toxicology and applied pharmacology.
[23] D. Vitarella. Development of an inhalation system for the simultaneous exposure of rat dams and pups during developmental neurotoxicity studies , 1998 .
[24] C. Martínez,et al. Blood Manganese Correlates with Brain Magnetic Resonance Imaging Changes in Patients with Liver Disease , 1996, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.
[25] Jean Lambert,et al. Bioaccumulation and locomotor effects of manganese sulfate in Sprague-Dawley rats following subchronic (90 days) inhalation exposure. , 2006, Toxicology and applied pharmacology.
[26] D. Dorman,et al. Direct olfactory transport of inhaled manganese ((54)MnCl(2)) to the rat brain: toxicokinetic investigations in a unilateral nasal occlusion model. , 2000, Toxicology and applied pharmacology.
[27] C S Moon,et al. Motor neuron disease on the Kii Peninsula of Japan: excess manganese intake from food coupled with low magnesium in drinking water as a risk factor. , 1994, The Science of the total environment.
[28] D. Dorman,et al. Influence of particle solubility on the delivery of inhaled manganese to the rat brain: manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure. , 2001, Toxicology and applied pharmacology.
[29] R. D. Du Pasquier,et al. Chronic parkinsonism associated with cirrhosis: a distinct subset of acquired hepatocerebral degeneration. , 2003, Archives of neurology.
[30] A. Pasi,et al. Manganese intoxication. , 1975, The Western journal of medicine.
[31] P Apostoli,et al. Long-term exposure to "low levels" of manganese oxides and neurofunctional changes in ferroalloy workers. , 1999, Neurotoxicology.
[32] K. Ljung,et al. Time to Re-evaluate the Guideline Value for Manganese in Drinking Water? , 2007, Environmental health perspectives.
[33] Brian A Wong,et al. Maternal-fetal distribution of manganese in the rat following inhalation exposure to manganese sulfate. , 2005, Neurotoxicology.
[34] D. Gallaher,et al. Biliary manganese excretion in conscious rats is affected by acute and chronic manganese intake but not by dietary fat. , 1996, The Journal of nutrition.
[35] S. Fredstrom,et al. Extrapyramidal symptoms in a BMT recipient with hyperintense basal ganglia and elevated manganese. , 1995, Bone marrow transplantation.
[36] J. Roth,et al. Iron interactions and other biological reactions mediating the physiological and toxic actions of manganese. , 2003, Biochemical pharmacology.
[37] H. Clewell,et al. Application of physiological computational fluid dynamics models to predict interspecies nasal dosimetry of inhaled acrolein. , 2008, Inhalation toxicology.
[38] Roberto Lucchini,et al. Adequacy and Consistency of Animal Studies to Evaluate the Neurotoxicity of Chronic Low-Level Manganese Exposure in Humans , 2007, Journal of toxicology and environmental health. Part A.
[39] D. Dorman,et al. Tissue manganese concentrations in lactating rats and their offspring following combined in utero and lactation exposure to inhaled manganese sulfate. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.
[40] M. Andersen,et al. Evaluating transport of manganese from olfactory mucosa to striatum by pharmacokinetic modeling. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[41] Furchner Je,et al. Comparative metabolism of radionuclides in mammals. 3. retention of manganese-54 in the mouse, rat, monkey and dog. , 1966 .
[42] D T Mage,et al. The EPA Health Risk Assessment of Methylcyclopentadienyl Manganese Tricarbonyl (MMT) , 1998, Risk analysis : an official publication of the Society for Risk Analysis.
[43] M. Andersen,et al. Pharmacokinetic Modeling of Manganese in the Rat IV: Assessing Factors that Contribute to Brain Accumulation During Inhalation Exposure , 2008, Journal of toxicology and environmental health. Part A.
[44] M E Andersen,et al. Modeling receptor-mediated processes with dioxin: implications for pharmacokinetics and risk assessment. , 1993, Risk analysis : an official publication of the Society for Risk Analysis.
[45] D. Dorman,et al. Tissue manganese concentrations in young male rhesus monkeys following subchronic manganese sulfate inhalation. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[46] Richard T. Miller,et al. Neurotoxicity of manganese chloride in neonatal and adult CD rats following subchronic (21‐day) high‐dose oral exposure , 2000, Journal of applied toxicology : JAT.
[47] Carlos Santos-Burgoa,et al. Motor alterations associated with exposure to manganese in the environment in Mexico. , 2006, The Science of the total environment.
[48] M. Andersen,et al. Pharmacokinetic Modeling of Manganese. III. Physiological Approaches Accounting for Background and Tracer Kinetics , 2007, Journal of toxicology and environmental health. Part A.
[49] A. Beuter,et al. Diadochokinesimetry: a study of patients with Parkinson's disease and manganese exposed workers. , 1994, Neurotoxicology.
[50] M. Andersen,et al. Pharmacokinetic Modeling of Manganese. I. Dose Dependencies of Uptake and Elimination , 2007, Journal of toxicology and environmental health. Part A.
[51] David C. Dorman,et al. Manganese Dosimetry: Species Differences and Implications for Neurotoxicity , 2005, Critical reviews in toxicology.
[52] Donna Mergler,et al. Manganese distribution in the brain and neurobehavioral changes following inhalation exposure of rats to three chemical forms of manganese. , 2004, Neurotoxicology.
[53] H. Roels,et al. Assessment of the permissible exposure level to manganese in workers exposed to manganese dioxide dust. , 1992, British journal of industrial medicine.
[54] P. Trumbo,et al. Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. , 1998, Journal of the American Dietetic Association.
[55] C. Richmond,et al. Comparative metabolism of radionuclides in mammals. 3. retention of manganese-54 in the mouse, rat, monkey and dog. , 1966, Health physics.
[56] R. Butterworth,et al. Increased blood manganese in cirrhotic patients: Relationship to pallidal magnetic resonance signal hyperintensity and neurological symptoms , 1996, Hepatology.
[57] Melvin E Andersen,et al. Dose-dependent transitions in mechanisms of toxicity. , 2004, Toxicology and applied pharmacology.
[58] C. Dolea,et al. World Health Organization , 1949, International Organization.
[59] M. Andersen,et al. Manganese tissue dosimetry in rats and monkeys: accounting for dietary and inhaled Mn with physiologically based pharmacokinetic modeling. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.
[60] G. Cartwright,et al. COPPER METABOLISM IN NORMAL SUBJECTS. , 1964, The American journal of clinical nutrition.
[61] A. Hazell,et al. ASSESSMENT OF BIOACCUMULATION AND NEUROTOXICITY IN RATS WITH PORTACAVAL ANASTOMOSIS AND EXPOSED TO MANGANESE PHOSPHATE: A PILOT STUDY , 2001, Inhalation toxicology.
[62] M. Andersen,et al. Pharmacokinetic data needs to support risk assessments for inhaled and ingested manganese. , 1999, Neurotoxicology.
[63] K. Sumino,et al. Heavy metals in normal Japanese tissues. Amounts of 15 heavy metals in 30 subjects. , 1975, Archives of environmental health.
[64] David C. Dorman,et al. OLFACTORY TRANSPORT: A DIRECT ROUTE OF DELIVERY OF INHALED MANGANESE PHOSPHATE TO THE RAT BRAIN , 2002, Journal of toxicology and environmental health. Part A.
[65] I. H. Tipton,et al. Trace elements in human tissue. II. Adult subjects from the United States. , 1963, Health physics.
[66] D. Dorman,et al. Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation. , 2007, American journal of industrial medicine.
[67] C. Martínez,et al. Manganese intoxication and chronic liver failure , 1994, Annals of Neurology.
[68] N. Krebs,et al. Development of a compartmental model of human zinc metabolism: identifiability and multiple studies analyses. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.
[69] R Tardif,et al. Nervous system dysfunction among workers with long-term exposure to manganese. , 1994, Environmental research.
[70] D. Krewski,et al. Bioaccumulation and locomotor effects of manganese phosphate/sulfate mixture in Sprague-Dawley rats following subchronic (90 days) inhalation exposure. , 2003, Toxicology and applied pharmacology.
[71] D. Dorman,et al. Brain manganese concentrations in rats following manganese tetroxide inhalation are unaffected by dietary manganese intake. , 2002, Neurotoxicology.
[72] I. H. Tipton,et al. Trace elements in human tissue. A need for standards. , 1970, The American journal of clinical nutrition.
[73] R. Butterworth,et al. Accumulation of manganese and copper in pallidum of cirrhotic patients: role in the pathogenesis of hepatic encephalopathy? , 1995, Metabolic Brain Disease.
[74] I. H. Tipton,et al. TRACE ELEMENTS IN HUMAN TISSUE. PART II. ADULT SUBJECTS FROM THE UNITED STATES , 1963 .
[75] M. Thompson,et al. The nervous system effects of occupational exposure to manganese--measured as respirable dust--in a South African manganese smelter. , 2005, Neurotoxicology.
[76] D M Foster,et al. Zinc metabolism in humans: a kinetic model. , 1984, The American journal of physiology.
[77] É. Lerebours,et al. Neurologic disorders due to brain manganese deposition in a jaundiced patient receiving long-term parenteral nutrition. , 1997, JPEN. Journal of parenteral and enteral nutrition.
[78] Michael Aschner,et al. Nutritional aspects of manganese homeostasis. , 2005, Molecular aspects of medicine.
[79] J. Everitt,et al. Nasal Toxicity of Manganese Sulfate and Manganese Phosphate in Young Male Rats Following Subchronic (13-Week) Inhalation Exposure , 2004, Inhalation toxicology.
[81] Ross W. Filice,et al. Diffusion abnormalities of the globi pallidi in manganese neurotoxicity , 2004, Neuroradiology.
[82] Dietrich H. Nies,et al. How Cells Control Zinc Homeostasis , 2007, Science.
[83] Atsushi Takeda,et al. Manganese action in brain function , 2003, Brain Research Reviews.
[84] D. Dorman,et al. Pulmonary clearance of manganese phosphate, manganese sulfate, and manganese tetraoxide by CD rats following intratracheal instillation. , 2000, Inhalation toxicology.
[85] Harvey J Clewell,et al. Application of pharmacokinetic data to the risk assessment of inhaled manganese. , 2006, Neurotoxicology.
[86] A. Iregren. Psychological test performance in foundry workers exposed to low levels of manganese. , 1990, Neurotoxicology and teratology.
[87] G C COTZIAS,et al. Manganese in health and disease. , 1958, Physiological reviews.
[88] W. Watson,et al. Use of mathematical modeling to study copper metabolism in humans. , 2005, The American journal of clinical nutrition.
[89] P Apostoli,et al. Neurobehavioral effects of manganese in workers from a ferroalloy plant after temporary cessation of exposure. , 1995, Scandinavian journal of work, environment & health.
[90] Michigan.,et al. Toxicological profile for dichloropropenes , 2008 .
[91] D. Krewski,et al. Neuropathology, tremor and electromyogram in rats exposed to manganese phosphate/sulfate mixture , 2006, Journal of applied toxicology : JAT.
[92] A. Hazell,et al. Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate. , 2002, Toxicology and applied pharmacology.
[93] F C Wedler,et al. Glutamine synthetase: the major Mn(II) enzyme in mammalian brain. , 1984, Current topics in cellular regulation.
[94] Y. Thomassen,et al. Neuropsychological function in manganese alloy plant workers , 2004, International archives of occupational and environmental health.
[95] D. Dorman,et al. Old age and gender influence the pharmacokinetics of inhaled manganese sulfate and manganese phosphate in rats. , 2004, Toxicology and applied pharmacology.
[96] Eric J. Esswein,et al. The nervous system effects of occupational exposure on workers in a South African manganese smelter. , 2003, Neurotoxicology.
[97] Roberto G Lucchini,et al. High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries. , 2007, American journal of industrial medicine.