Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets.
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H. Noushmehr | D. Harlan | S. Li Calzi | R. Perfetti | A. Bulotta | U. di Mario | B. Hirshberg | L. Farilla | Nasif Khoury | C. Bertolotto
[1] J. Schölmerich,et al. Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations. , 2002, Journal of molecular endocrinology.
[2] D. Drucker. Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. , 2003, Molecular endocrinology.
[3] R. Perfetti,et al. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. , 2002, Endocrinology.
[4] J. Holst. Therapy of type 2 diabetes mellitus based on the actions of glucagon‐like peptide‐1 , 2002, Diabetes/metabolism research and reviews.
[5] S. Bonner-Weir,et al. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. , 1999, Diabetes.
[6] H. Edlund. Factors controlling pancreatic cell differentiation and function , 2001, Diabetologia.
[7] D. Drucker,et al. Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy. , 2003, Diabetes.
[8] K. Roth,et al. In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system , 1998, Cell Death and Differentiation.
[9] M. Prentki,et al. Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor , 2003 .
[10] Jie Zhou,et al. Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells. , 1999, Diabetes.
[11] J. Habener,et al. Glucagon-like peptide 1 increases glucose-dependent activity of the homeoprotein IDX-1 transactivating domain in pancreatic β-cells , 2000 .
[12] B. Friedrichsen,et al. Regulation of-Cell Mass by Hormones and Growth Factors , 2001 .
[13] R. Perfetti,et al. Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5'-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway. , 2003, Endocrinology.
[14] M. Prentki,et al. Protein Kinase Cζ Activation Mediates Glucagon-Like Peptide-1–Induced Pancreatic β-Cell Proliferation , 2001 .
[15] C. Ricordi,et al. Improved Human Islet Isolation Using a New Enzyme Blend, Liberase , 1997, Diabetes.
[16] N. Greig,et al. Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats. , 1997, The Journal of clinical investigation.
[17] C. Deacon,et al. The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice. , 2002, American journal of physiology. Endocrinology and metabolism.
[18] C. Rhodes,et al. IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication. , 2000, Journal of molecular endocrinology.
[19] H. Seers,et al. OUTCOME , 1977, How to Win Your Case.
[20] M. Itakura,et al. Transgenic expression of FGF8 and FGF10 induces transdifferentiation of pancreatic islet cells into hepatocytes and exocrine cells. , 2002, Biochemical and biophysical research communications.
[21] Hideki Taniguchi,et al. Glucagon-like peptide 1 (1–37) converts intestinal epithelial cells into insulin-producing cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[22] Michael B Wheeler,et al. The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion. , 2002, Diabetes.
[23] A. F. Stewart,et al. Using β-Cell Growth Factors to Enhance Human Pancreatic Islet Transplantation* , 2001 .
[24] A. Hardikar,et al. Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin. , 2002, Endocrinology.
[25] B. Friedrichsen,et al. Regulation of beta-cell mass by hormones and growth factors. , 2001, Diabetes.
[26] S. Bonner-Weir,et al. ENHANCED MATURATION OF PORCINE NEONATAL PANCREATIC CELL CLUSTERS WITH GROWTH FACTORS FAILS TO IMPROVE TRANSPLANTATION OUTCOME1 , 2001, Transplantation.
[27] E. Ryan,et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. , 2000, The New England journal of medicine.
[28] D. Harlan,et al. Islet transplantation as a treatment for diabetes. , 2004, The New England journal of medicine.
[29] A. F. Stewart,et al. Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice. , 2001, Diabetes.
[30] J. Habener,et al. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. , 2002, Endocrinology.
[31] Yazhou Li,et al. Glucagon-like Peptide-1 Receptor Signaling Modulates β Cell Apoptosis* , 2003, The Journal of Biological Chemistry.
[32] B. Tyrberg,et al. β-Cell Differentiation from a Human Pancreatic Cell Line in Vitro and in Vivo , 2001 .
[33] J. Holst,et al. Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure. , 1998, Diabetes care.
[34] J. Egan,et al. Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. , 2000, Endocrinology.
[35] B. Portha,et al. Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age. , 2001, Diabetes.
[36] B. Portha,et al. Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. , 2002, Diabetes.