Asymmetric cortical surface area and morphology changes in mesial temporal lobe epilepsy with hippocampal sclerosis

Purpose:  To date, magnetic resonance imaging (MRI)–based studies of the cerebral cortex in mesial temporal lobe epilepsy (MTLE) have focused primarily on investigating cortical volume and thickness. However, volume is a composite of surface area and thickness, each reflecting distinct neurobiologic and genetic processes. The goal of this study was to investigate cerebral cortex (1) surface area, (2) surface geometric distortion, and (3) thickness in MTLE with hippocampal sclerosis (HS).

[1]  J. Thornton,et al.  Rapid stereological quantitation of temporal neocortex in TLE. , 2003, Magnetic resonance imaging.

[2]  A. Cerasa,et al.  Neocortical thinning in “benign” mesial temporal lobe epilepsy , 2011, Epilepsia.

[3]  G. Jackson,et al.  Preoperative MRI predicts outcome of temporal lobectomy , 1995, Neurology.

[4]  Norman Delanty,et al.  Cerebral Cortical Gyrification: A Preliminary Investigation in Temporal Lobe Epilepsy , 2007, Epilepsia.

[5]  Gary W. Mathern,et al.  Erratum: Definition of drug resistant epilepsy. Consensus proposal by the ad hoc task force of the ILAE commission on therapeutic strategies (Epilepsia (2010) 51 (1069-77)) , 2010 .

[6]  J D Watson,et al.  Nonparametric Analysis of Statistic Images from Functional Mapping Experiments , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[7]  Frederick Andermann,et al.  Hippocampal sclerosis in temporal lobe epilepsy demonstrated by magnetic resonance imaging , 1991, Annals of neurology.

[8]  Ingrid Agartz,et al.  A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations , 2009, Proceedings of the National Academy of Sciences.

[9]  W. Feindel,et al.  Entorhinal cortex in temporal lobe epilepsy , 1999, Neurology.

[10]  Michael Seidenberg,et al.  Cerebellar atrophy in temporal lobe epilepsy , 2005, Epilepsy & Behavior.

[11]  Agatha D. Lee,et al.  Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis. , 2007, Cerebral cortex.

[12]  G. Mathern,et al.  Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. , 2002, Progress in brain research.

[13]  L Lemieux,et al.  Extrahippocampal temporal lobe atrophy in temporal lobe epilepsy and mesial temporal sclerosis. , 2001, Brain : a journal of neurology.

[14]  Philippe Kahane,et al.  The temporopolar cortex plays a pivotal role in temporal lobe seizures. , 2005, Brain : a journal of neurology.

[15]  M. Weiner,et al.  Impact of Methodologic Choice for Automatic Detection of Different Aspects of Brain Atrophy by Using Temporal Lobe Epilepsy as a Model , 2011, American Journal of Neuroradiology.

[16]  Abraham Z. Snyder,et al.  A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume , 2004, NeuroImage.

[17]  E. Halgren,et al.  Side Matters: Diffusion Tensor Imaging Tractography in Left and Right Temporal Lobe Epilepsy , 2009, American Journal of Neuroradiology.

[18]  J. Morris,et al.  Differential effects of aging and Alzheimer's disease on medial temporal lobe cortical thickness and surface area , 2009, Neurobiology of Aging.

[19]  G. Cavalleri,et al.  A cross-sectional MRI study of brain regional atrophy and clinical characteristics of temporal lobe epilepsy with hippocampal sclerosis , 2012, Epilepsy Research.

[20]  Alan C. Evans,et al.  Brain size and cortical structure in the adult human brain. , 2008, Cerebral cortex.

[21]  A. Schleicher,et al.  The ontogeny of human gyrification. , 1995, Cerebral cortex.

[22]  H. Wieser,et al.  Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis , 2004 .

[23]  S. Heckers,et al.  Abnormal cortical folding patterns within Broca's area in schizophrenia: Evidence from structural MRI , 2007, Schizophrenia Research.

[24]  P. Schauwecker.  Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death , 2003, Epilepsy Research.

[25]  Fabrice Wendling,et al.  Entorhinal Cortex Involvement in Human Mesial Temporal Lobe Epilepsy: An Electrophysiologic and Volumetric Study , 2005, Epilepsia.

[26]  A. Dale,et al.  Cortical Surface-Based Analysis II: Inflation, Flattening, and a Surface-Based Coordinate System , 1999, NeuroImage.

[27]  S. Spencer,et al.  Hippocampal resections and the use of human tissue in defining temporal lobe epilepsy syndromes , 1994, Hippocampus.

[28]  Peter F. Liddle,et al.  Regional contraction of brain surface area involves three large-scale networks in schizophrenia , 2011, Schizophrenia Research.

[29]  E. Halgren,et al.  Subcortical and cerebellar atrophy in mesial temporal lobe epilepsy revealed by automatic segmentation , 2008, Epilepsy Research.

[30]  Eric Halgren,et al.  Regional neocortical thinning in mesial temporal lobe epilepsy , 2008, Epilepsia.

[31]  Peter F. Liddle,et al.  Differential effects of surface area, gyrification and cortical thickness on voxel based morphometric deficits in schizophrenia , 2012, NeuroImage.

[32]  M. Brodie,et al.  Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies , 2011 .

[33]  D. Arnold,et al.  Mesial temporal damage in temporal lobe epilepsy: a volumetric MRI study of the hippocampus, amygdala and parahippocampal region. , 2003, Brain : a journal of neurology.

[34]  N. Voets,et al.  Increased temporolimbic cortical folding complexity in temporal lobe epilepsy , 2010, Neurology.

[35]  Vincent Magnotta,et al.  Quantitative measurement of cortical surface features in localization-related temporal lobe epilepsy. , 2004, Neuropsychology.

[36]  A MEYER,et al.  PATHOLOGICAL FINDINGS IN TEMPORAL LOBE EPILEPSY , 1954, Journal of neurology, neurosurgery, and psychiatry.

[37]  D. V. Essen,et al.  A tension-based theory of morphogenesis and compact wiring in the central nervous system , 1997, Nature.

[38]  N. Andreasen,et al.  Gyrification abnormalities in childhood- and adolescent-onset schizophrenia , 2003, Biological Psychiatry.

[39]  N. Roberts,et al.  Voxel‐based morphometry of temporal lobe epilepsy: An introduction and review of the literature , 2008, Epilepsia.

[40]  P. Kellaway,et al.  Proposal for Revised Clinical and Electroencephalographic Classification of Epileptic Seizures , 1981, Epilepsia.

[41]  Michael Weiner,et al.  Widespread neocortical abnormalities in temporal lobe epilepsy with and without mesial sclerosis , 2009, NeuroImage.

[42]  A. Dale,et al.  Distinct genetic influences on cortical surface area and cortical thickness. , 2009, Cerebral cortex.

[43]  G. Mathern,et al.  Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies , 2009, Epilepsia.

[44]  Anders M. Dale,et al.  Cortical Surface-Based Analysis I. Segmentation and Surface Reconstruction , 1999, NeuroImage.

[45]  A. Dale,et al.  High‐resolution intersubject averaging and a coordinate system for the cortical surface , 1999, Human brain mapping.

[46]  Matcheri S. Keshavan,et al.  Increased frontal cortical folding in autism: a preliminary MRI study , 2004, Psychiatry Research: Neuroimaging.

[47]  Sébastien Ourselin,et al.  Head size, age and gender adjustment in MRI studies: a necessary nuisance? , 2010, NeuroImage.

[48]  Alan C. Evans,et al.  Longitudinal and cross-sectional analysis of atrophy in pharmacoresistant temporal lobe epilepsy , 2009, Neurology.

[49]  Anders M. Dale,et al.  Reliability of MRI-derived measurements of human cerebral cortical thickness: The effects of field strength, scanner upgrade and manufacturer , 2006, NeuroImage.

[50]  Ari Syngeniotis,et al.  Seizure‐associated hippocampal volume loss: A longitudinal magnetic resonance study of temporal lobe epilepsy , 2002, Annals of neurology.

[51]  Ayse Pinar Saygin,et al.  Smoothing and cluster thresholding for cortical surface-based group analysis of fMRI data , 2006, NeuroImage.

[52]  P. Rakic.  Specification of cerebral cortical areas. , 1988, Science.