Prevalence of common mental disorders in general practice attendees across Europe

Background There is evidence that the prevalence of common mental disorders varies across Europe. Aims To compare prevalence of common mental disorders in general practice attendees in six European countries. Method Unselected attendees to general practices in the UK, Spain, Portugal, Slovenia, Estonia and The Netherlands were assessed for major depression, panic syndrome and other anxiety syndrome. Prevalence of DSM–IV major depression, other anxiety syndrome and panic syndrome was compared between the UK and other countries after taking account of differences in demographic factors and practice consultation rates. Results Prevalence was estimated in 2344 men and 4865 women. The highest prevalence for all disorders occurred in the UK and Spain, and lowest in Slovenia and The Netherlands. Men aged 30–50 and women aged 18–30 had the highest prevalence of major depression; men aged 40–60 had the highest prevalence of anxiety, and men and women aged 40–50 had the highest prevalence of panic syndrome. Demographic factors accounted for the variance between the UK and Spain but otherwise had little impact on the significance of observed country differences. Conclusions These results add to the evidence for real differences between European countries in prevalence of psychological disorders and show that the burden of care on general practitioners varies markedly between countries.

[1]  R. Kravitz,et al.  Depression , 2007, Annals of Internal Medicine.

[2]  J. Lépine,et al.  Treatment adequacy for anxiety and depressive disorders in six European countries , 2007, British Journal of Psychiatry.

[3]  Jan Neeleman,et al.  Prediction of depression in European general practice attendees: the PREDICT study , 2006, BMC public health.

[4]  Robert B. Innis,et al.  Sex Differences in Diencephalon Serotonin Transporter Availability in Major Depression , 2006, Biological Psychiatry.

[5]  M. Ansseau,et al.  Prevalence and impact of generalized anxiety disorder and major depression in primary care in Belgium and Luxemburg: the GADIS study , 2005, European Psychiatry.

[6]  M. Heitor,et al.  [Depressive disorder burden: global epidemiological issues and information needs in Portugal]. , 2005, Acta medica portuguesa.

[7]  Kenneth S Kendler,et al.  Sex differences in the relationship between social support and risk for major depression: a longitudinal study of opposite-sex twin pairs. , 2005, The American journal of psychiatry.

[8]  F. Mazzi,et al.  Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project , 2004, Acta psychiatrica Scandinavica. Supplementum.

[9]  Ronald C. Kessler,et al.  The National Comorbidity Survey , 2003 .

[10]  C. Reynolds,et al.  A contemporary protocol to assist primary care physicians in the treatment of panic and generalized anxiety disorders. , 2003, General hospital psychiatry.

[11]  G. Simon.  Evidence review: efficacy and effectiveness of antidepressant treatment in primary care. , 2002, General hospital psychiatry.

[12]  M. Craske,et al.  Treating panic disorder in primary care: a collaborative care intervention. , 2002, General hospital psychiatry.

[13]  Hans-Ulrich Wittchen,et al.  Generalized anxiety disorder: prevalence, burden, and cost to society , 2002, Depression and anxiety.

[14]  M. Höfler,et al.  Prevalence and recognition of depressive syndromes in German primary care settings: poorly recognized and treated? , 2001, International clinical psychopharmacology.

[15]  E. Aragonés Benaiges,et al.  [Prevalence and characteristics of major depression and dysthymia in primary care]. , 2001, Atencion primaria.

[16]  M. Olfson,et al.  Prevalence of anxiety, depression, and substance use disorders in an urban general medicine practice. , 2000, Archives of family medicine.

[17]  Juan de Dios Luna,et al.  Validity of self reported utilisation of primary health care services in an urban population in Spain , 2000, Journal of epidemiology and community health.

[18]  R. Spitzer,et al.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. , 1999, JAMA.

[19]  A Jordan,et al.  Depression in Europe , 1999, British Journal of Psychiatry.

[20]  G. Dunn,et al.  Mental health in primary care , 1997, British Journal of Psychiatry.

[21]  J. Lépine,et al.  Depression in the community: the first pan‐European study DEPRES (Depression Research in European Society) , 1997, International clinical psychopharmacology.

[22]  F. O'Kelly.  Psychiatry and general practice today . Ian Pullen, Greg Wilkinson, Alister Wright, Denis Pereira Gray, Editors. London: Royal College of Psychiatrists/ Royal College of General Practitioners, 1994. £17.50. , 1994 .

[23]  G. Wilkinson,et al.  Psychiatry and General Practice Today , 1994 .

[24]  R. Kessler,et al.  The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey. , 1994, The American journal of psychiatry.

[25]  J. Ormel,et al.  Outcome of depression and anxiety in primary care. A three-wave 3 1/2-year study of psychopathology and disability. , 1993, Archives of general psychiatry.

[26]  Peter Huxley,et al.  Common mental disorders : a bio-social model , 1992 .

[27]  D. C. Olivier,et al.  Affective disorders and mortality. A general population study. , 1987, Archives of general psychiatry.

[28]  M. Shepherd,et al.  Minor psychiatric morbidity and general practice consultation: the West London Survey. , 1986, Psychological medicine. Monograph supplement.

[29]  Rachel Jenkins.  Minor psychiatric morbidity in employed young men and women and its contribution to sickness absence. , 1985, British journal of industrial medicine.