Evaluation of effectiveness of endovascular embolisation for the treatment of pelvic congestion syndrome--preliminary study.

OBJECTIVES The Aim: The aim of the study was to evaluate the effectiveness, safety and clinical outcomes of endovascular embolisation of pelvic congestion syndrome (PCS). MATERIAL AND METHODS This prospective, observational study carried out between January and May of 2014 encompassed 24 female patients aged 22-44 years (average - 31 years) diagnosed with PCS. Diagnosis of PCS was established by medical history physical examination, transvaginal Doppler ultrasound examination and confirmed by MRI. The patients were qualified for phlebography and ovarian vein embolization with 0.035" detachable coils and/or microcoils. Pelvic pain scores were assessed before and 3 months after the procedure with the visual analog scale (VAS; 0 - no pain, 10 - unbearable pain). RESULTS Embolisation procedures were performed in 23 out of 24 patients. Nineteen patients underwent unilateral and 4 patients bilateral embolisation of the ovarian vein. In one case, safe and selective vessel catheterization was not possible due to the anatomical variant of venous flow. Nineteen patients underwent unilateral embolisation of the left ovarian vein. Four patients had the left and right ovarian veins embolized; in one of them, the internal iliac vein was additionally closed (the two-stage procedure). The technical success rate was 96%. Procedures lasted 23-78 minutes (32 minutes on average). An average of 40 ml of contrast was administered during the procedures. The total mean radiation dose at the reference point was 389 mGy (from 127 mGy to 1112 mGy). A decrease in pelvic pain intensity according to VAS was considered a clinical success. The median VAS pelvic pain score before the procedure was 8. Three months after the procedure median pelvic pain score decreased to 1 (p < 0.001). In two cases, the ovarian vein was injured and the contrast medium extravasated, which was clinically insignificant. In one case, a small injection site haematoma developed. CONCLUSION Embolisation is a minimally invasive, effective and safe method of treatment for PCS. The cooperation between gynaecologists and interventional radiologists is essential for successful outcomes.

[1]  M. Bekiesińska-Figatowska [Magnetic resonance imaging as a non-invasive detection tool for extraovarian endometriosis--own experience]. , 2014, Ginekologia polska.

[2]  Richard L. Hesketh,et al.  Pelvic congestion syndrome: etiology of pain, diagnosis, and clinical management. , 2014, Journal of vascular and interventional radiology : JVIR.

[3]  M. D. de Gregorio,et al.  Safety, efficacy, and prognostic factors in endovascular treatment of pelvic congestion syndrome , 2014, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[4]  M. A. Gregório,et al.  Endovascular Treatment of Pelvic Congestion Syndrome: Visual Analog Scale (VAS) Long-Term Follow-up Clinical Evaluation in 202 Patients , 2013, CardioVascular and Interventional Radiology.

[5]  G. Jahng,et al.  Time-resolved MR angiography for detecting and grading ovarian venous reflux: comparison with conventional venography. , 2012, The British journal of radiology.

[6]  K. Valji Comprar The Practice of Interventional Radiology, with online cases and video. Expert Consult Premium Edition - Enhanced Online Features and Print | Karim Valji | 9781437717198 | Saunders , 2011 .

[7]  K. Jin,et al.  Unusual causes of varicose veins in the lower extremities: CT venographic and Doppler US findings. , 2009, Radiographics : a review publication of the Radiological Society of North America, Inc.

[8]  F. Allaert,et al.  Embolisation of symptomatic pelvic veins in women presenting with non-saphenous varicose veins of pelvic origin - three-year follow-up. , 2007, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[9]  A. Davies,et al.  Pelvic congestion syndrome: chronic pelvic pain caused by ovarian and internal iliac varices , 2007, Phlebology.

[10]  J. Oh,et al.  Transcatheter Ovarian Vein Embolization Using Coils for the Treatment of Pelvic Congestion Syndrome , 2007, CardioVascular and Interventional Radiology.

[11]  Seong Jin Park,et al.  Diagnosis of pelvic congestion syndrome using transabdominal and transvaginal sonography. , 2004, AJR. American journal of roentgenology.

[12]  C. Huh,et al.  Comparison of treatments for pelvic congestion syndrome. , 2003, The Tohoku journal of experimental medicine.

[13]  Maya Cohen,et al.  Ovarian varices in healthy female kidney donors: incidence, morbidity, and clinical outcome. , 2002, AJR. American journal of roentgenology.

[14]  D. Mitchell,et al.  Ovarian veins: Magnetic resonance imaging findings in an asymptomatic population , 2002, Journal of magnetic resonance imaging : JMRI.

[15]  K. Vicdan,et al.  A randomized controlled trial of goserelin and medroxyprogesterone acetate in the treatment of pelvic congestion. , 2001, Human reproduction.

[16]  E. S. Amis,et al.  Incompetent and dilated ovarian veins: a common CT finding in asymptomatic parous women. , 2001, AJR. American journal of roentgenology.

[17]  G. Marchal,et al.  Ovarian vein embolization for the treatment of pelvic congestion syndrome: long-term technical and clinical results. , 2000, Journal of vascular and interventional radiology : JVIR.

[18]  H. Hricak,et al.  CT and MRI of pelvic varices in women. , 1999, Journal of computer assisted tomography.

[19]  S. Franks,et al.  A randomized controlled trial of medroxyprogesterone acetate and psychotherapy for the treatment of pelvic congestion , 1989, British journal of obstetrics and gynaecology.