Ganglion Cell Complex and Visual Recovery after Surgical Removal of Idiopathic Epiretinal Membranes

The presence of ganglion cell axons in the context of surgically removed idiopathic epiretinal membranes (ERMs) was reported recently in the literature. In this prospective observational study, we used spectral domain-optical coherence tomography to investigate the change in ganglion cell complex (GCC) thickness and its possible correlation with visual recovery after vitreoretinal surgery for idiopathic ERM. We analyzed best-corrected visual acuity, mean macular thickness and mean GCC thickness 1 day before surgery, and 7 and 180 days after surgery. Internal segment/outer segment junction, external limiting membrane, cone outer segment tips defects and intraretinal fluid were also investigated. The baseline GCC thickness was higher in patients with ERM (130 ± 13 μm) compared with healthy eyes (94 ± 5 μm; p