Highlights from the Flow Chemistry Literature 2016 (Part 1)

[1]  A. Lenhoff,et al.  Dispersion coefficient for laminar flow in curved tubes , 1988 .

[2]  Gunther Kolb,et al.  Development of a Microrectification Apparatus for Analytical and Preparative Applications , 2012 .

[3]  . S.N.Mandal,et al.  Gas—Liquid Flow Through Helical Coils in Horizontal Orientation , 2008 .

[4]  Krishna D.P. Nigam,et al.  Coiled flow inverter as an inline mixer , 2008 .

[5]  K. Jensen.  Microreaction engineering * is small better? , 2001 .

[6]  Krishna D.P. Nigam,et al.  CFD modeling of flow profiles and interfacial phenomena in two-phase flow in pipes , 2006 .

[7]  Nam-Trung Nguyen,et al.  Micromixers Based on Chaotic Advection , 2008 .

[8]  Surya Pratap Vanka,et al.  Numerical study of scalar mixing in curved channels at low Reynolds numbers , 2004 .

[9]  Volker Hessel,et al.  Copper(I)-catalyzed azide-alkyne cycloadditions in microflow: catalyst activity, high-T operation, and an integrated continuous copper scavenging unit. , 2012, ChemSusChem.

[10]  J. van der Schaaf,et al.  Liquid-liquid slug flow separation in a slit shaped micro device , 2012 .

[11]  Albert Renken,et al.  Influence of Flow Regime on Mass Transfer in Different Types of Microchannels , 2011 .

[12]  C. Oliver Kappe,et al.  Translating High-Temperature Microwave Chemistry to Scalable Continuous Flow Processes , 2010 .

[13]  Ville Alopaeus,et al.  Novel micro-distillation column for process development , 2009 .

[14]  Taisuke Maki,et al.  Liquid–liquid extraction for efficient synthesis and separation by utilizing micro spaces , 2008 .

[15]  M. N. Kashid,et al.  Numbering-up and mass transfer studies of liquid-liquid two-phase microstructured reactors , 2010 .

[16]  Volker Hessel,et al.  Implementation of heat integration for efficient process design of direct adipic synthesis in flow , 2013 .

[17]  V. M. Puri,et al.  Residence Time Distribution of Particles during Two-Phase Non-Newtonian Flow in Conventional as compared with Helical Holding Tubes , 1997 .

[18]  V. Hessel,et al.  Cross-Coupling Chemistry in Continuous Flow , 2014 .

[19]  Norbert Kockmann,et al.  Narrow residence time distribution in tubular reactor concept for Reynolds number range of 10–100 , 2015 .

[20]  Antoine Pallandre,et al.  Recent innovations in protein separation on microchips by electrophoretic methods: An update , 2010, Electrophoresis.

[21]  Volker Hessel,et al.  Photochemical transformations accelerated in continuous-flow reactors: basic concepts and applications. , 2014, Chemistry.

[22]  K. Nigam,et al.  Experimental investigation of void fraction and flow patterns in coiled flow inverter , 2008 .

[23]  H. Löwe,et al.  Chemistry in microstructured reactors. , 2004, Angewandte Chemie.

[24]  Klavs F. Jensen,et al.  Membrane-Based, Liquid–Liquid Separator with Integrated Pressure Control , 2013 .

[25]  E. Nauman.  The residence time distribution for laminar flow in helically coiled tubes , 1977 .

[26]  Steffen Hardt,et al.  Simulation of helical flows in microchannels , 2004 .

[27]  R. Adler,et al.  Minimisation of axial dispersion by use of secondary flow in helical tubes , 1964 .

[28]  K. Nigam,et al.  Augmentation of heat transfer performance in coiled flow inverter vis-à-vis conventional heat exchanger , 2010 .

[29]  K. Nigam,et al.  Liquid–Liquid Mixing in Coiled Flow Inverter , 2011 .

[30]  Krishna D.P. Nigam,et al.  Numerical simulation of steady flow fields in coiled flow inverter , 2005 .

[31]  Liwei Pan,et al.  Effects of Design and Operating Parameters on CO 2 Absorption in Microchannel Contactors , 2009 .

[32]  C. Kappe,et al.  Click chemistry under non-classical reaction conditions. , 2010, Chemical Society reviews.

[33]  J. Ottino.  The Kinematics of Mixing: Stretching, Chaos, and Transport , 1989 .

[34]  Olivier Lobet,et al.  Selective nitration in a microreactor for pharmaceutical production under cGMP conditions , 2009 .

[35]  Quan Yuan,et al.  Process Characteristics of CO2 Absorption by Aqueous Monoethanolamine in a Microchannel Reactor , 2012 .

[36]  Krishna D.P. Nigam,et al.  Prediction of flow profiles and interfacial phenomena for two-phase flow in coiled tubes , 2009 .

[37]  David A Barrow,et al.  Liquid-liquid phase separation: characterisation of a novel device capable of separating particle carrying multiphase flows. , 2009, Lab on a chip.

[38]  Krishna D.P. Nigam,et al.  Mixing in curved tubes , 2006 .

[39]  K. Jensen,et al.  Multistep continuous-flow microchemical synthesis involving multiple reactions and separations. , 2007, Angewandte Chemie.

[40]  Norbert Kockmann,et al.  Scale-up concept of single-channel microreactors from process development to industrial production , 2011 .

[41]  Volker Hessel,et al.  Solvent- and catalyst-free huisgen cycloaddition to rufinamide in flow with a greener, less expensive dipolarophile. , 2013, ChemSusChem.

[42]  Krishna D.P. Nigam,et al.  Liquid-Phase Residence Time Distribution for Two-Phase Flow in Coiled Flow Inverter , 2008 .

[43]  Yannick Hoarau,et al.  Numerical modeling of polystyrene synthesis in coiled flow inverter , 2011 .

[44]  David W. Agar,et al.  Hydrodynamics of liquid–liquid slug flow capillary microreactor: Flow regimes, slug size and pressure drop , 2007 .

[45]  C. Culbertson,et al.  Microchip devices for high-efficiency separations. , 2000, Analytical chemistry.

[46]  Norbert Kockmann,et al.  Novel three-dimensional microfluidic device for process intensification , 2014 .

[47]  Volker Hessel,et al.  Novel process windows for enabling, accelerating, and uplifting flow chemistry. , 2013, ChemSusChem.

[48]  Klavs F. Jensen,et al.  Kinetic and Scale-Up Investigations of Epoxide Aminolysis in Microreactors at High Temperatures and Pressures , 2011 .

[49]  Lei Shao,et al.  Removal of Carbon Dioxide by Absorption in Microporous Tube-in-Tube Microchannel Reactor , 2011 .

[50]  Jogender Singh,et al.  Flow Characteristics of Power-Law Fluids in Coiled Flow Inverter , 2013 .

[51]  David W. Agar,et al.  Liquid−Liquid Slug Flow in a Capillary: An Alternative to Suspended Drop or Film Contactors , 2007 .

[52]  Volker Hessel,et al.  Potential Analysis of Smart Flow Processing and Micro Process Technology for Fastening Process Development: Use of Chemistry and Process Design as Intensification Fields , 2012 .

[53]  Ryan L Hartman,et al.  Microchemical systems for continuous-flow synthesis. , 2009, Lab on a chip.

[54]  A Gavriilidis,et al.  Development of multistage distillation in a microfluidic chip. , 2011, Lab on a chip.

[55]  Ryan L Hartman,et al.  Multistep microchemical synthesis enabled by microfluidic distillation. , 2010, Angewandte Chemie.

[56]  Michael Finot,et al.  Capillary electrochromatography with packed bead beds in microfluidic devices , 2009, Electrophoresis.

[57]  Dominique M. Roberge,et al.  Development of an Industrial Multi‐Injection Microreactor for Fast and Exothermic Reactions – Part II , 2008 .

[58]  R. S. Deelder,et al.  Measurement of axial dispersion in laminar flow through coiled capillary tubes , 1979 .

[59]  Volker Hessel,et al.  Liquid–Liquid Flow in a Capillary Microreactor: Hydrodynamic Flow Patterns and Extraction Performance , 2012 .

[60]  Krishna D.P. Nigam,et al.  A Review on the Potential Applications of Curved Geometries in Process Industry , 2008 .

[61]  Timothy Noël,et al.  Suzuki-Miyaura cross-coupling reactions in flow: multistep synthesis enabled by a microfluidic extraction. , 2011, Angewandte Chemie.

[62]  Volker Hessel,et al.  Novel Process Windows – Gate to Maximizing Process Intensification via Flow Chemistry , 2009 .

[63]  Victor M Ugaz,et al.  Fluid mixing in planar spiral microchannels. , 2006, Lab on a chip.

[64]  Martin D. Johnson,et al.  Development of Safe and Scalable Continuous-Flow Methods for Palladium-Catalyzed Aerobic Oxidation Reactions. , 2010, Green chemistry : an international journal and green chemistry resource : GC.

[65]  I. Mezić,et al.  Chaotic Mixer for Microchannels , 2002, Science.

[66]  Stephen Wiggins,et al.  Foundations of chaotic mixing , 2004, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[67]  D. Agar,et al.  The capillary-microreactor: a new reactor concept for the intensification of heat and mass transfer in liquid–liquid reactions , 2003 .

[68]  Eugeny Y. Kenig,et al.  Micro-separation of fluid systems: A state-of-the-art review , 2013 .

[69]  Krishna D.P. Nigam,et al.  Flow regimes, hold–up and pressure drop for two phase flowin helical coils , 1990 .

[70]  Jogender Singh,et al.  The thermal and transport characteristics of nanofluids in a novel three-dimensional device , 2014 .

[71]  Holger Löwe,et al.  Aqueous Kolbe−Schmitt Synthesis Using Resorcinol in a Microreactor Laboratory Rig under High-p,T Conditions , 2005 .

[72]  Volker Hessel,et al.  Life cycle assessment for the direct synthesis of adipic acid in microreactors and benchmarking to the commercial process , 2013 .

[73]  David W. Agar,et al.  Effective interfacial area for mass transfer in the liquid-liquid slug flow capillary microreactors , 2010 .

[74]  C. Minnich,et al.  Determination of the Dispersion Characteristics of Miniaturized Coiled Reactors with Fiber-Optic Fourier Transform Mid-infrared Spectroscopy , 2010 .

[75]  V. Hessel,et al.  Micromixers—a review on passive and active mixing principles , 2005 .

[76]  V. Hessel,et al.  Novel process window for the safe and continuous synthesis of tert.-butyl peroxy pivalate in a micro reactor , 2011 .

[77]  Krishna D.P. Nigam,et al.  Laminar dispersion in helically coiled tubes of square cross‐section , 1983 .

[78]  K. Nigam,et al.  Experimental Investigation of Pressure Drop during Two-Phase Flow in a Coiled Flow Inverter , 2007 .

[79]  V. Hessel,et al.  Continuous metal scavenging and coupling to one-pot copper-catalyzed azide-alkyne cycloaddition click reaction in flow , 2015 .

[80]  C. Oliver Kappe,et al.  Continuous flow organic synthesis under high-temperature/pressure conditions. , 2010, Chemistry, an Asian journal.

[81]  V. Hessel,et al.  Process-design intensification : direct synthesis of adipic acid in flow , 2012 .

[82]  K. Jensen,et al.  Integrated continuous microfluidic liquid-liquid extraction. , 2007, Lab on a chip.

[83]  M.H.J.M. de Croon,et al.  Novel process windows – Concept, proposition and evaluation methodology, and intensified superheated processing , 2011 .

[84]  Ryan L Hartman,et al.  Distillation in microchemical systems using capillary forces and segmented flow. , 2009, Lab on a chip.

[85]  Krist V. Gernaey,et al.  Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator , 2012 .

[86]  Steffen Hardt,et al.  Helical Flows and Chaotic Mixing in Curved Micro Channels , 2004 .

[87]  Volker Hessel,et al.  Micro process engineering : a comprehensive handbook , 2009 .

[88]  K. T. Shenoy,et al.  Liquid–Liquid Two-Phase Flow Patterns in a Serpentine Microchannel , 2012 .

[89]  T. Míšek.  Standard test systems for liquid extraction , 1985 .

[90]  P. Rohr,et al.  Liquid Extraction of Vanillin in Rectangular Microreactors , 2008 .

[91]  K. Nigam,et al.  Laminar dispersion of polymer solutions in helical coils , 1981 .

[92]  Girija Jayaraman,et al.  Numerical simulation of dispersion in the flow of power law fluids in curved tubes , 1994 .

[93]  Volker Hessel,et al.  Potenzialanalyse von Milli- und Mikroprozesstechniken für die Verkürzung von Prozessentwicklungszeiten : Chemie und Prozessdesign als Intensivierungsfelder , 2012 .

[94]  Krishna D.P. Nigam,et al.  Coiled configuration for flow inversion and its effect on residence time distribution , 1984 .

[95]  Yuchao Zhao,et al.  Liquid‐liquid two‐phase flow patterns in a rectangular microchannel , 2006 .

[96]  V. Hessel,et al.  Pressure-accelerated azide-alkyne cycloaddition: micro capillary versus autoclave reactor performance. , 2015, ChemSusChem.

[97]  C. Oliver Kappe,et al.  Continuous‐Flow Microreactor Chemistry under High‐Temperature/Pressure Conditions , 2009 .

[98]  S. Pushpavanam,et al.  Experimental and Numerical Investigations of Two-Phase (Liquid−Liquid) Flow Behavior in Rectangular Microchannels , 2010 .

[99]  Peter Styring,et al.  From discovery to production: Scale-out of continuous flow meso reactors , 2009, Beilstein journal of organic chemistry.

[100]  V. Hessel,et al.  Improving energy efficiency of process of direct adipic acid synthesis in flow using pinch analysis , 2013 .

[101]  Norbert Kockmann,et al.  Axial Dispersion and Heat Transfer in a Milli/Microstructured Coiled Flow Inverter for Narrow Residence Time Distribution at Laminar Flow , 2015 .

[102]  Krishna D.P. Nigam,et al.  Liquid phase residence time distribution for two phase flow in coiled tubes , 1996 .

[103]  V. Hessel,et al.  Catalyst retention in continuous flow with supercritical carbon dioxide , 2014 .

[104]  Albert Renken,et al.  Liquid-liquid two-phase flow patterns and mass transfer characteristics in rectangular glass microreactors , 2008 .

[105]  J. Burns,et al.  The intensification of rapid reactions in multiphase systems using slug flow in capillaries. , 2001, Lab on a chip.

[106]  Volker Hessel,et al.  Sustainability through green processing – novel process windows intensify micro and milli process technologies , 2008 .

[107]  Timothy Noël,et al.  Cross-coupling in flow. , 2011, Chemical Society reviews.

[108]  P. Rohr,et al.  Continuous Micro Liquid‐Liquid Extraction , 2013 .

[109]  K. Nigam,et al.  Coiled flow inverter as a heat exchanger , 2007 .

[110]  L. Janssen.  Axial dispersion in laminar flow through coiled tubes , 1976 .

[111]  Paul Watts,et al.  Recent advances in micro reaction technology. , 2011, Chemical communications.

[112]  Volker Hessel,et al.  Microchemical Engineering: Components, Plant Concepts, User Acceptance – Part II , 2003 .