Pregnancy among Women Undergoing Intrauterine Insemination in a Centre

Introduction: Intrauterine insemination is often performed as the first-line treatment option in many subfertility cases. Successful intrauterine insemination treatment among indicated couples helps to reduce unnecessary in-vitro fertilisation treatment. Although widely practised, the data on pregnancy after intrauterine insemination treatment is limited. The aim of this study was to find out the prevalence of pregnancy among women undergoing intrauterine insemination in a centre. Methods: A descriptive cross-sectional study was conducted at a centre among women undergoing intrauterine insemination. Data from 15 May 2017 to 15 April 2021 were collected between 16 June 2022 to 1 July 2022 from the hospital records. Ethical approval was taken from the Nepal Health Research Council. Systematic sampling technique was applied to select the appropriate sample. The point estimate was calculated at a 95% Confidence Interval. Results: Among 225 women undergoing intrauterine insemination, pregnancy was achieved in 23 (10.22%) (6.26-14.18, 95% Confidence Interval). The mean age of pregnant women was 29.17±3.34 years and the mean duration of infertility was 3.93±2.90 years. More than half of the pregnant women 13 (56.52%) had undergone insemination with the husband’s semen whereas the remaining 10 women (43.48%) had undergone insemination with donor semen. Conclusions: The prevalence of pregnancy among women undergoing intrauterine insemination was similar to other studies done in similar settings.

[1]  M. Hemadi,et al.  Oocyte quality and aging , 2021, JBRA assisted reproduction.

[2]  LiSha Tang,et al.  Pregnancy Predictors in Unexplained Infertility after Intrauterine Insemination. , 2021, Journal of gynecology obstetrics and human reproduction.

[3]  O. Ishihara,et al.  International Committee for Monitoring Assisted Reproductive Technologies world report: assisted reproductive technology 2012†. , 2020, Human reproduction.

[4]  Shyam Sundar Parajuly,et al.  Outcome of Intra Uterine Insemination in Sahara International Fertility Centre Pokhara, Nepal , 2018, Medical Journal of Pokhara Academy of Health Sciences.

[5]  W. Ombelet,et al.  IUI: review and systematic assessment of the evidence that supports global recommendations , 2018, Human reproduction update.

[6]  P. Navarro,et al.  Prognostic factors in intrauterine insemination cycles , 2018, JBRA assisted reproduction.

[7]  F. Ghaffari,et al.  Evaluating The Effective Factors in Pregnancy after Intrauterine Insemination: A Retrospective Study , 2015, International journal of fertility & sterility.

[8]  M. Soria,et al.  Pregnancy Predictors after Intrauterine Insemination: Analysis of 3012 Cycles in 1201 Couples , 2012, Journal of reproduction & infertility.

[9]  M. A. Norsina,et al.  Associated factors affecting the successful pregnancy rate of intrauterine insemination at International Islamic University Malaysia (IIUM) Fertility Centre. , 2011, The Medical journal of Malaysia.

[10]  B. Haydardedeoglu,et al.  Single versus double intrauterine insemination in multi-follicular ovarian hyperstimulation cycles: a randomized trial. , 2010, Human reproduction.

[11]  E. Bosmans,et al.  Intrauterine insemination (IUI) as a first-line treatment in developing countries and methodological aspects that might influence IUI success , 2008 .

[12]  J. Ikechebelu,et al.  Intrauterine insemination with controlled ovarian stimulation for treatment of infertility: An audit of a new IUI programme in a low resource setting , 2007, Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology.

[13]  J. Vioque,et al.  Analysis of factors influencing pregnancy rates in homologous intrauterine insemination. , 2004, Fertility and sterility.

[14]  R. Dickey,et al.  Effect of diagnosis, age, sperm quality, and number of preovulatory follicles on the outcome of multiple cycles of clomiphene citrate-intrauterine insemination. , 2002, Fertility and sterility.

[15]  M. Ashrafi,et al.  Relationship between sperm parameters and clinical outcomes of Intra Uterine Insemination (IUI) , 2021, Caspian journal of internal medicine.