Specific activation of the alpha 7 nicotinic acetylcholine receptor by a quaternary analog of cocaine.
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R E Oswald | R. Oswald | M. Francis | M M Francis | E Y Cheng | G A Weiland | G. Weiland | E. Cheng
[1] J. Macor,et al. (-)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin-2'-one], a conformationally restricted analogue of acetylcholine, is a highly selective full agonist at the alpha 7 nicotinic acetylcholine receptor. , 2000, Journal of medicinal chemistry.
[2] A. Fox,et al. Neuronal α-Bungarotoxin Receptors Differ Structurally from Other Nicotinic Acetylcholine Receptors , 1997, The Journal of Neuroscience.
[3] R. Oswald,et al. Identification of a new amino acid residue capable of modulating agonist efficacy at the homomeric nicotinic acetylcholine receptor, alpha7. , 1999, Molecular pharmacology.
[4] R Freedman,et al. Nicotinic receptor function in schizophrenia. , 1996, Schizophrenia bulletin.
[5] E. Albuquerque,et al. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes. , 1993, The Journal of pharmacology and experimental therapeutics.
[6] E. Albuquerque,et al. Molecular mechanisms of the potent and stereospecific nicotinic receptor agonist (+)-anatoxin-a. , 1986, Molecular pharmacology.
[7] R. Lukas,et al. Similarity Between Rat Brain Nicotinic α‐Bungarotoxin Receptors and Stably Expressed α‐Bungarotoxin Binding Sites , 1996 .
[8] M. Quik,et al. Nicotinic receptors and Parkinson's disease. , 2000, European journal of pharmacology.
[9] D. Bertrand,et al. Stable expression and pharmacological properties of the human alpha 7 nicotinic acetylcholine receptor. , 1995, European journal of pharmacology.
[10] R. Papke,et al. Analysis of 3-(4-hydroxy, 2-Methoxybenzylidene)anabaseine selectivity and activity at human and rat alpha-7 nicotinic receptors. , 1998, The Journal of pharmacology and experimental therapeutics.
[11] William R Kem,et al. The brain α7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21) , 2000, Behavioural Brain Research.
[12] J. Udgaonkar,et al. Chemical kinetic measurements of a mammalian acetylcholine receptor by a fast-reaction technique. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[13] R. Papke,et al. Characterization of a series of anabaseine-derived compounds reveals that the 3-(4)-dimethylaminocinnamylidine derivative is a selective agonist at neuronal nicotinic alpha 7/125I-alpha-bungarotoxin receptor subtypes. , 1995, Molecular pharmacology.
[14] D. K. Berg,et al. Detection of Functional Nicotinic Receptors Blocked by α-Bungarotoxin on PC12 Cells and Dependence of Their Expression on Post-Translational Events , 1997, The Journal of Neuroscience.
[15] R. Maue,et al. Nerve growth factor increases nicotinic ACh receptor gene expression and current density in wild-type and protein kinase A-deficient PC12 cells , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[16] W. Sweileh,et al. Multistep expression and assembly of neuronal nicotinic receptors is both host-cell- and receptor-subtype-dependent. , 2000, Brain research. Molecular brain research.
[17] J. Sullivan,et al. Activation of the recombinant human alpha 7 nicotinic acetylcholine receptor significantly raises intracellular free calcium. , 1997, The Journal of pharmacology and experimental therapeutics.
[18] D. Clifford,et al. Nicotinic acetylcholine currents in cultured postnatal rat hippocampal neurons. , 1992, Molecular pharmacology.
[19] E. Neher,et al. Local anaesthetics transiently block currents through single acetylcholine‐receptor channels. , 1978, The Journal of physiology.
[20] J. Patrick,et al. Amino Acid Determinants of α7 Nicotinic Acetylcholine Receptor Surface Expression* , 2000, The Journal of Biological Chemistry.
[21] D. Sagher,et al. α-Bungarotoxin Receptors Contain α7 Subunits in Two Different Disulfide-Bonded Conformations , 1999, The Journal of cell biology.
[22] J. Daly,et al. Epibatidine, a potent analgetic and nicotinic agonist. , 1994, Molecular pharmacology.
[23] R. Lukas,et al. Similarity between rat brain nicotinic alpha-bungarotoxin receptors and stably expressed alpha-bungarotoxin binding sites. , 1996, Journal of neurochemistry.
[24] P. De Koninck,et al. Agonist and toxin sensitivities of ACh-evoked currents on neurons expressing multiple nicotinic ACh receptor subunits. , 1995, Journal of neurophysiology.
[25] R. Papke,et al. An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the α7 subtype , 1996, Neuroscience Letters.
[26] W. N. Green,et al. Neuronal α-Bungarotoxin Receptors Are α7 Subunit Homomers , 2000, The Journal of Neuroscience.
[27] D. Bertrand,et al. Functional expression of nicotinic acetylcholine receptors containing rat α7 subunits in human SH‐SY5Y neuroblastoma cells , 1994, FEBS letters.
[28] Y. Cheng,et al. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. , 1973, Biochemical pharmacology.
[29] Zhong-Wei Zhang,et al. Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels , 1994, Neuron.
[30] S. Heinemann,et al. The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[31] T. Lewis,et al. The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type , 1997, The Journal of physiology.
[32] R. Papke,et al. The correction of alpha7 nicotinic acetylcholine receptor concentration-response relationships in Xenopus oocytes , 1998, Neuroscience Letters.
[33] D. Bertrand,et al. Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. , 1996, The Journal of physiology.
[34] J. B. Pitner,et al. N-modified analogues of cocaine: synthesis and inhibition of binding to the cocaine receptor. , 1992, Journal of medicinal chemistry.
[35] W. N. Green,et al. Neuronal alpha-bungarotoxin receptors are alpha7 subunit homomers. , 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[36] R. Papke,et al. Subtype-Selective Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Cocaine Is Determined by the α4 and β4 Subunits , 2000 .
[37] N. Millar,et al. Host Cell‐Specific Folding and Assembly of the Neuronal Nicotinic Acetylcholine Receptor α7 Subunit , 1997, Journal of neurochemistry.