Space physiology VI: exercise, artificial gravity, and countermeasure development for prolonged space flight

[1]  M. Heer,et al.  Effects of vibration training on bone metabolism: results from a short-term bed rest study , 2012, European Journal of Applied Physiology.

[2]  M. Custaud,et al.  Peripheral Arterial and Venous Response to Tilt Test after a 60-Day Bedrest with and without Countermeasures (ES-IBREP) , 2012, PloS one.

[3]  D. Felsenberg,et al.  Resistive vibration exercise during bed-rest reduces motor control changes in the lumbo-pelvic musculature. , 2012, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[4]  T. R. Phillips,et al.  Artificial gravity training reduces bed rest-induced cardiovascular deconditioning , 2012, European Journal of Applied Physiology.

[5]  C. Rubin,et al.  Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner. , 2011, Journal of applied physiology.

[6]  Larry A Kramer,et al.  Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. , 2011, Ophthalmology.

[7]  D. Felsenberg,et al.  Bone structure and density via HR-pQCT in 60d bed-rest, 2-years recovery with and without countermeasures. , 2011, Journal of musculoskeletal & neuronal interactions.

[8]  B. Franklin,et al.  American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. , 2011, Medicine and science in sports and exercise.

[9]  D. Felsenberg,et al.  Differential atrophy of the postero-lateral hip musculature during prolonged bedrest and the influence of exercise countermeasures. , 2011, Journal of applied physiology.

[10]  C. Kang,et al.  Impact of simulated microgravity on microvascular endothelial cell apoptosis , 2011, European Journal of Applied Physiology.

[11]  Steven H. Platts,et al.  Cardiovascular exercise in the U.S. space program: Past, present and future , 2010 .

[12]  Stuart M. C. Lee,et al.  WISE-2005: exercise and nutrition countermeasures for upright VO2pk during bed rest. , 2009, Medicine and science in sports and exercise.

[13]  Alan R. Hargens,et al.  Cardiovascular adaptations, fluid shifts, and countermeasures related to space flight , 2009, Respiratory Physiology & Neurobiology.

[14]  V J Caiozzo,et al.  Artificial gravity as a countermeasure to microgravity: a pilot study examining the effects on knee extensor and plantar flexor muscle groups. , 2009, Journal of applied physiology.

[15]  Danny A Riley,et al.  Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. , 2009, Journal of applied physiology.

[16]  Stuart M. C. Lee,et al.  LBNP exercise protects aerobic capacity and sprint speed of female twins during 30 days of bed rest. , 2009, Journal of applied physiology.

[17]  Donald E. Watenpaugh,et al.  WISE-2005: effect of aerobic and resistive exercises on orthostatic tolerance during 60 days bed rest in women , 2009, European Journal of Applied Physiology.

[18]  R. Hughson,et al.  Insufficient flow reduction during LBNP in both splanchnic and lower limb areas is associated with orthostatic intolerance after bedrest. , 2008, American journal of physiology. Heart and circulatory physiology.

[19]  D. Zawieja,et al.  Diminished mesenteric vaso- and venoconstriction and elevated plasma ANP and BNP with simulated microgravity. , 2008, Journal of applied physiology.

[20]  Kiril Minchev,et al.  Human soleus single muscle fiber function with exercise or nutrition countermeasures during 60 days of bed rest. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[21]  Stuart M. C. Lee,et al.  Lower body negative pressure exercise plus brief postexercise lower body negative pressure improve post-bed rest orthostatic tolerance. , 2007, Journal of applied physiology.

[22]  Marc T. Hamilton,et al.  Role of Low Energy Expenditure and Sitting in Obesity, Metabolic Syndrome, Type 2 Diabetes, and Cardiovascular Disease , 2007, Diabetes.

[23]  R. Hughson,et al.  WISE 2005: chronic bed rest impairs microcirculatory endothelium in women. , 2007, American journal of physiology. Heart and circulatory physiology.

[24]  Kiril Minchev,et al.  Single muscle fiber function with concurrent exercise or nutrition countermeasures during 60 days of bed rest in women. , 2007, Journal of applied physiology.

[25]  Stuart M. C. Lee,et al.  Supine LBNP exercise maintains exercise capacity in male twins during 30-d bed rest. , 2007, Medicine and science in sports and exercise.

[26]  M. Narici,et al.  From space to Earth: advances in human physiology from 20 years of bed rest studies (1986–2006) , 2007, European Journal of Applied Physiology.

[27]  G. Biolo,et al.  Cardiac atrophy in women following bed rest , 2007, Journal of applied physiology.

[28]  Laurence R Young,et al.  Centrifugation protocol for the NASA Artificial Gravity-Bed Rest Pilot Study. , 2007, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology.

[29]  André Diedrich,et al.  Plasma and blood volume in space. , 2007, The American journal of the medical sciences.

[30]  A. Hargens,et al.  LBNP treadmill exercise maintains spine function and muscle strength in identical twins during 28-day simulated microgravity. , 2007, Journal of applied physiology.

[31]  R. S. Meyer,et al.  TESTING EXERCISE COUNTERMEASURES DURING 30 DAYS OF SIMULATED MICROGRAVITY: LESSONS LEARNED FROM STUDIES OF IDENTICAL TWINS , 2007 .

[32]  W. Paloski,et al.  Gender Differences in Cardiovascular Tolerance to Short Arm Centrifugation , 2007 .

[33]  Scott M Smith,et al.  Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins. , 2007, Bone.

[34]  R. Wolfe,et al.  Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress. , 2006, The Journal of clinical endocrinology and metabolism.

[35]  Peter R Cavanagh,et al.  Gravity replacement during running in simulated microgravity. , 2006, Aviation, space, and environmental medicine.

[36]  S. Bloomfield,et al.  Does altered blood flow to bone in microgravity impact on mechanotransduction? , 2006, Journal of musculoskeletal & neuronal interactions.

[37]  Manoj Monga,et al.  Renal stone risk in a simulated microgravity environment: impact of treadmill exercise with lower body negative pressure. , 2006, The Journal of urology.

[38]  M. Delp,et al.  Endothelium-dependent vasodilation of cerebral arteries is altered with simulated microgravity through nitric oxide synthase and EDHF mechanisms. , 2006, Journal of applied physiology.

[39]  D. Stegeman,et al.  Strength, size and activation of knee extensors followed during 8 weeks of horizontal bed rest and the influence of a countermeasure , 2006, European Journal of Applied Physiology.

[40]  S. Besnard,et al.  Portal vein cross-sectional area and flow and orthostatic tolerance: a 90-day bed rest study. , 2005, Journal of applied physiology.

[41]  Toshiaki Ueno,et al.  Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest. , 2005, Journal of applied physiology.

[42]  C. Alfrey,et al.  The Negative Regulation of Red Cell Mass by Neocytolysis: Physiologic and Pathophysiologic Manifestations , 2005, Cellular Physiology and Biochemistry.

[43]  M. Delp,et al.  Simulated microgravity enhances cerebral artery vasoconstriction and vascular resistance through endothelial nitric oxide mechanism. , 2005, American journal of physiology. Heart and circulatory physiology.

[44]  Scott M Smith,et al.  The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station. , 2005, The Journal of nutrition.

[45]  Li-fan Zhang Vascular adaptation to microgravity. , 2004, Journal of applied physiology.

[46]  H. Akima,et al.  Effect of centrifuge-induced artificial gravity and ergometric exercise on cardiovascular deconditioning, myatrophy, and osteoporosis induced by a -6 degrees head-down bedrest. , 2004, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology.

[47]  P A Tesch,et al.  Efficacy of a gravity-independent resistance exercise device as a countermeasure to muscle atrophy during 29-day bed rest. , 2004, Acta physiologica Scandinavica.

[48]  Matthew Harber,et al.  Human single muscle fibre function with 84 day bed‐rest and resistance exercise , 2004, The Journal of physiology.

[49]  Satoshi Iwase,et al.  Effectiveness of centrifuge-induced artificial gravity with ergometric exercise as a countermeasure during simulated microgravity exposure in humans. , 2003, Acta astronautica.

[50]  Scott M Smith,et al.  Evaluation of Treadmill Exercise in a Lower Body Negative Pressure Chamber as a Countermeasure for Weightlessness‐Induced Bone Loss: A Bed Rest Study With Identical Twins , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[51]  Martina Heer,et al.  Bone resorption is induced on the second day of bed rest: results of a controlled crossover trial. , 2003, Journal of applied physiology.

[52]  Yasuo Kawakami,et al.  Resistance training during unweighting maintains muscle size and function in human calf. , 2003, Medicine and science in sports and exercise.

[53]  Donald E. Watenpaugh,et al.  Lower-body negative-pressure exercise and bed-rest-mediated orthostatic intolerance. , 2002, Medicine and science in sports and exercise.

[54]  D. Watenpaugh,et al.  Fluid volume control during short-term space flight and implications for human performance. , 2001, The Journal of experimental biology.

[55]  K Hirayanagi,et al.  Usefulness of daily +2Gz load as a countermeasure against physiological problems during weightlessness. , 2001, Acta astronautica.

[56]  R. Fitts,et al.  Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function. , 2001, Journal of applied physiology.

[57]  L. Suva,et al.  Microgravity: a Possible Mechanism for Bone Remodeling Alterations in Skeletal Perfusion with Simulated , 2022 .

[58]  A. Hargens,et al.  Supine lower body negative pressure exercise simulates metabolic and kinetic features of upright exercise. , 2000, Journal of applied physiology.

[59]  A R Hargens,et al.  Supine Lower Body Negative Pressure Exercise During Bed Rest Maintains Upright Exercise Capacity. , 2000, Journal of applied physiology.

[60]  T. Fukunaga,et al.  Leg-press resistance training during 20 days of 6° head-down-tilt bed rest prevents muscle deconditioning , 2000, European Journal of Applied Physiology.

[61]  J. Greenleaf,et al.  Short-arm (1.9 m) +2.2 Gz acceleration: isotonic exercise load-O2 uptake relationship. , 1999, Aviation, space, and environmental medicine.

[62]  T P Stein,et al.  Protein kinetics during and after long-duration spaceflight on MIR. , 1999, American journal of physiology. Endocrinology and metabolism.

[63]  T P Stein,et al.  Energy expenditure and balance during spaceflight on the space shuttle. , 1999, The American journal of physiology.

[64]  F. B. Davis,et al.  Thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells. , 1999, American journal of physiology. Cell physiology.

[65]  J. East,et al.  Intra-ocular pressure changes during maximal isometric contraction: does this reflect intra-cranial pressure or retinal venous pressure? , 1999, Neurological research.

[66]  B D Levine,et al.  Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance. , 1997, Circulation.

[67]  Stuart M. C. Lee,et al.  Upright exercise or supine lower body negative pressure exercise maintains exercise responses after bed rest. , 1997, Medicine and science in sports and exercise.

[68]  R. Wolfe,et al.  Resistance exercise maintains skeletal muscle protein synthesis during bed rest. , 1997, Journal of applied physiology.

[69]  J I Leonard,et al.  Regulation of body fluid compartments during short-term spaceflight. , 1996, Journal of applied physiology.

[70]  R. Wolfe,et al.  Prolonged bed rest decreases skeletal muscle and whole body protein synthesis. , 1996, The American journal of physiology.

[71]  I B Kozlovskaya,et al.  Countermeasure of the negative effects of weightlessness on physical systems in long-term space flights. , 1995, Acta astronautica.

[72]  S. Arnaud,et al.  Changes in markers of bone formation and resorption in a bed rest model of weightlessness , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[73]  Karl Kirsch,et al.  Fluid shifts into and out of superficial tissues under microgravity and terrestrial conditions , 1993, The clinical investigator.

[74]  A G Crenshaw,et al.  Transcapillary fluid responses to lower body negative pressure. , 1993, Journal of applied physiology.

[75]  A R Hargens,et al.  Transcapillary fluid shifts in tissues of the head and neck during and after simulated microgravity. , 1991, Journal of applied physiology.

[76]  D. Sale,et al.  Arterial blood pressure response to heavy resistance exercise. , 1985, Journal of applied physiology.

[77]  R. M. Peters,et al.  Normal transcapillary pressures in human skeletal muscle and subcutaneous tissues. , 1981, Microvascular research.

[78]  Katkov Ve,et al.  Blood pressure and oxygenation in different cardiovascular compartments of a normal man during postural exposures. , 1980 .

[79]  V. Pubul,et al.  and Cardiovascular Disease: What to , 2019 .

[80]  Victor A. Convertino,et al.  Exercise and Adaptation to Microgravity Environments , 2011 .

[81]  A. Hargens,et al.  The Cardiovascular System in Microgravity , 2011 .

[82]  Victor S. Schneider,et al.  The Physiology of Bed Rest , 2011 .

[83]  F. Booth,et al.  Fundamental questions about genes, inactivity, and chronic diseases. , 2007, Physiological genomics.

[84]  A. Leblanc,et al.  Skeletal responses to space flight and the bed rest analog: a review. , 2007, Journal of musculoskeletal & neuronal interactions.

[85]  William H Paloski,et al.  Gender differences in cardiovascular tolerance to short radius centrifugation. , 2007, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology.

[86]  T. Fukunaga,et al.  Leg-press resistance training during 20 days of 6 degrees head-down-tilt bed rest prevents muscle deconditioning. , 2000, European journal of applied physiology.

[87]  P R Cavanagh,et al.  Evaluation of a Treadmill with Vibration Isolation and Stabilization (TVIS) for use on the International Space Station. , 1999, Journal of applied biomechanics.

[88]  Daniel L. Feeback,et al.  Impact of resistance exercise during bed rest on skeletal muscle sarcopenia and myosin isoform distribution. , 1998, Journal of applied physiology.

[89]  M Rubin,et al.  The physiology of bed rest. , 1988, The American journal of nursing.

[90]  V. Katkov,et al.  Blood pressure and oxygenation in different cardiovascular compartments of a normal man during postural exposures. , 1980, Aviation, space, and environmental medicine.

[91]  E. G. Gibson Skylab 4 crew observations , 1977 .