Inflammatory and infectious skin diseases in line-field confocal optical coherence tomography: state of the art.

Line-field confocal optical coherence tomography (LC-OCT) is a new non-invasive dermatological imaging device. We summarized the available data on the use of LC-OCT for inflammatory and infectious diseases. In February 2023, we searched for all articles concerning the use of LC-OCT in inflammatory and infectious diseases. A total number of 14 papers were found and evaluated, and relevant information was extracted. LC-OCT can reveal architectural changes in the skin. Inflammatory cells are barely visible. It can highlight the level of fluid accumulation, the thickness of different epidermal layers, and the presence of ''foreign bodies'' such as parasites.

[1]  K. Peris,et al.  Comparison of reflectance confocal microscopy and line‐field optical coherence tomography for the identification of keratinocyte skin tumours , 2022, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[2]  A. Di Stefani,et al.  Sharpen your sight: Trombiculosis under the dermatoscope with LC‐OCT new insights , 2022, Dermatologic therapy.

[3]  A. Di Stefani,et al.  Line‐field confocal optical coherence tomography (LC‐OCT) in Hailey–Hailey disease: another brick in the wall , 2022, International journal of dermatology.

[4]  E. Cinotti,et al.  Line‐field confocal optical coherence tomography for the diagnosis of nodular scabies mimicking breast cancer skin metastasis , 2022, International journal of dermatology.

[5]  J. Malvehy,et al.  Morphological evaluation of melanocytic lesions with three‐dimensional line‐field confocal optical coherence tomography: correlation with histopathology and reflectance confocal microscopy. A pilot study , 2022, Clinical and experimental dermatology.

[6]  E. Cinotti,et al.  Line‐field confocal optical coherence tomography imaging of human cowpox virus skin infection , 2022, Journal of the European Academy of Dermatology and Venereology : JEADV.

[7]  C. Miracco,et al.  Line‐field confocal optical coherence tomography: a new tool for non‐invasive differential diagnosis of pustular skin disorders , 2022, Journal of the European Academy of Dermatology and Venereology : JEADV.

[8]  F. Lacarrubba,et al.  Line‐field confocal optical coherence tomography of psoriasis, eczema and lichen planus: a case series with histopathological correlation , 2022, Journal of the European Academy of Dermatology and Venereology : JEADV.

[9]  J. Malvehy,et al.  Non-invasive scoring of cellular atypia in keratinocyte cancers in 3D LC-OCT images using Deep Learning , 2022 .

[10]  D. Hartmann,et al.  Line‐field confocal optical coherence tomography for the in vivo real‐time diagnosis of different stages of keratinocyte skin cancer: a preliminary study , 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

[11]  F. Lacarrubba,et al.  Line‐field confocal optical coherence tomography in molluscum contagiosum: a case series , 2021, Journal of the European Academy of Dermatology and Venereology.

[12]  P. Rubegni,et al.  Line‐field confocal optical coherence tomography for non‐invasive diagnosis of lichenoid dermatoses of the childhood: A case series , 2021, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[13]  D. Hartmann,et al.  Line‐field optical coherence tomography: in vivo diagnosis of basal cell carcinoma subtypes compared with histopathology , 2021, Clinical and experimental dermatology.

[14]  F. Lacarrubba,et al.  Line‐field confocal optical coherence tomography of xanthogranuloma: Correlation with vertical and horizontal histopathology , 2021, Journal of cutaneous pathology.

[15]  J. Malvehy,et al.  Line‐field confocal optical coherence tomography of sebaceous hyperplasia: a case series , 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

[16]  F. Lacarrubba,et al.  Line‐field confocal optical coherence tomography: a novel, non‐invasive imaging technique for a rapid, in‐vivo diagnosis of herpes infection of the skin , 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

[17]  J. Malvehy,et al.  Line field confocal optical coherence tomography: An adjunctive tool in the diagnosis of autoimmune bullous diseases , 2021, Journal of biophotonics.

[18]  D. Hartmann,et al.  Noninvasive real‐time imaging of mite skin infestations with line‐field confocal optical coherence tomography , 2020, The British journal of dermatology.

[19]  Julia Welzel,et al.  Line‐field confocal optical coherence tomography—Practical applications in dermatology and comparison with established imaging methods , 2020, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[20]  J. Malvehy,et al.  In vivo characterization of healthy human skin with a novel, non‐invasive imaging technique: line‐field confocal optical coherence tomography , 2020, Journal of the European Academy of Dermatology and Venereology : JEADV.

[21]  P. Rubegni,et al.  New findings in non‐invasive imaging of aquagenic keratoderma: Line‐field optical coherence tomography, dermoscopy and reflectance confocal microscopy , 2020, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[22]  P. Rubegni,et al.  Kaposi sarcoma of the glans: New findings by line field confocal optical coherence tomography examination , 2020, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[23]  P. Rubegni,et al.  Delayed Tattoo Reaction From Red Dye With Overlapping Clinicopathological Features: Examination With High-Frequency Ultrasound and Line-Field Optical Coherence Tomography , 2020, Dermatology practical & conceptual.

[24]  E. Sattler,et al.  In vivo imaging of Sarcoptes scabiei infestation using line‐field confocal optical coherence tomography , 2020, Journal of the European Academy of Dermatology and Venereology : JEADV.