论文信息 - Two benzoylaminoacridinedione derivatives

Two benzoylaminoacridinedione derivatives

The title compounds, 10-benzoylamino-1,2,3,4,5,6,7,8,9, 10-decahydroacridine-1,8-dione monohydrate, C(20)H(20)N(2)O(3).H(2)O, and 10-p-toluoylamino-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1, 8-dione monohydrate, C(21)H(22)N(2)O(3).H(2)O, consist of partially hydrogenated acridine moieties with one benzoylamino substituent on the central ring. The acridine moiety suffers considerable deviations from planarity. The central ring in the acridine moiety is a boat, while the outer rings adopt sofa conformations.

[1] M. Nardelli,et al. PARST95 – an update to PARST: a system of Fortran routines for calculating molecular structure parameters from the results of crystal structure analyses , 1995 .

[2] J. Fouassier,et al. Photoinitiated polymerization of acrylates and methacrylates with decahydroacridine-1,8-dione/onium salt initiator systems , 1993 .

[3] H. M. Sobell,et al. Visualization of drug--nucleic acid interactions at atomic resolution. V. Structure of two aminoacridine--dinucleoside monophosphate crystalline complexes, proflavine--5-iodocytidylyl (3'-5') guanosine and acridine orange--5-iodocytidylyl (3'-5') guanosine. , 1979, Journal of molecular biology.

[4] H. M. Sobell,et al. Visualization of drug-nucleic acid interactions at atomic resolution. IV. Structure of an aminoacridine--dinucleoside monophosphate crystalline complex, 9-aminoacridine--5-iodocytidylyl (3'--5') guanosine. , 1979, Journal of molecular biology.

[5] D. Cremer,et al. General definition of ring puckering coordinates , 1975 .

[6] A. Peacocke,et al. The interaction of aminoacridines with nucleic acids , 1968, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.