Experimental Studies on Reimplantation of Autogenous Bone Decalcified by Combined HCl and Ultrasonic Exposure

Decalcified bone implants induce new bone formation. In this experiment, the autogenous bone implant of canine mandible was treated by HCl under ultrasonic exposure for rapid decalcification. The aim of this study was to investigate the osteoinduction property of this rapidly decalcified bone reimplanted to the original site. The decalcified bone implant exhibited a similar degree of new formation to that of the fresh bone graft which was not subjected to decalcification. The results demonstrate that the combinational use of HCl and ultrasonic exposure for rapid decalcification treatment preserves the regenerative capacity of bone to be implanted.

[1]  K. Nakano,et al.  Aging and Ectopic Bone Formation Induced by Partially Purified Bone Morphogenetic Protein : Blood Vessel Ingrowth and Localization of Type I Collagen and Osteocalcin Assessed by Immunohistochemistry , 1997 .

[2]  K. Sano,et al.  Experimental studies on ultrasonic decalcification of bone implants. , 1991 .

[3]  K. Sano,et al.  Studies on heat treatment for immediate reimplantation of resected bone. , 1991, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[4]  E. Campbell,et al.  Bone banking. A cost effective method for establishing a community hospital bone bank. , 1986, Clinical Orthopaedics and Related Research.

[5]  R. Ewers,et al.  The autoclaved autogenous reimplant, an immediately replaced, mineral frame. , 1986, Journal of maxillofacial surgery.

[6]  R. Ewers,et al.  The autoclaved autogenous bone graft as a re-implant. Results of animal experiments. , 1986, Journal of Maxillofacial Surgery.

[7]  N. Takano,et al.  Reconstruction procedures of jaw bones by using reimplantation of resected jaw portion treated by freezing and warming. , 1985 .

[8]  Y. Homma [Experimental studies on healing process after the sagittal splitting technic in the dog mandible]. , 1985, Shika gakuho. Dental science reports.

[9]  H. Kurihara [Healing processes in freeze-dried homogeneous bone grafts in the dog mandible]. , 1985, Shika gakuho. Dental science reports.

[10]  K. Omura,et al.  Mandibular reconstruction with reimplantation of the boiled autogenous bone , 1984 .

[11]  H. Mankin,et al.  1983 bone bank procedures. , 1983, Clinical orthopaedics and related research.

[12]  M. Trachtenberg,et al.  Ultrasonic decalcification of bone. , 1981, The American journal of surgical pathology.

[13]  R. Hamaker Irradiated autogenous mandibular grafts in primary reconstructions. , 1981, The Laryngoscope.

[14]  Urist Bone transplants and implants , 1980 .

[15]  C. W. Cummings,et al.  Experimental Observations of Canine Mandibular Regeneration following Segmental Removal, Freezing, and Reimplantation , 1978 .

[16]  R. D. Marciani,et al.  Reimplantation of freeze-treated mandibular bone. , 1975, Journal of oral surgery.

[17]  A. Weaver,et al.  Frozen autogenous mandibular stent-graft for immediate reconstruction in oral cancer surgery. , 1973, American journal of surgery.

[18]  P. Hackett,et al.  Mandibular bone grafts with surface decalcified bone. , 1972, The Journal of Oral Surgery.

[19]  M. Urist Surface-decalcified allogeneic bone (SDAB) implants. A preliminary report of 10 cases and 25 comparable operations with undecalcified lyophilized bone implants. , 1968, Clinical orthopaedics and related research.

[20]  M. Urist,et al.  The accessibility of the bone induction principle in surface-decalcified bone implants. , 1967, Clinical orthopaedics and related research.

[21]  F. Poston Bone decalcification expedited by ultrasonic sound. , 1967, The American journal of medical technology.

[22]  R. E. Morris,et al.  Studies on demineralization of bone. I. The basic factors of demineralization. , 1956, American journal of clinical pathology.