Effect of Adding Dexamethasone to Bupivacaine on Transversus Abdominis Plane Block [Transversus Abdominis Plane Bloğa Eklenen Deksametazonun Etkisi] -

We aimed to evaluate the effect of dexamethasone added TAP block on postoperative analgesia accompanied by ultrasound in the TAH. After obtaining the Ethics Committee and the patient's consent a total of 60 ASA I-II patients undergoing planned total abdominal hysterectomy with general anesthesia were enrolled in the study. After surgical termination, ultrasound guided TAP block was performed by the same anesthesiologist. The patients were randomly divided into two groups using the envelope method. TAP block was obtained with 19 mL of bupivacaine hydrochloride 0.25%+1 mLsaline 0.9% (Group B, n=30) or 19 mL of bupivacaine hydrochloride 0.25%+1 mLdexamethasone (4 mg) (Group BD, n=30). Postoperatif pain scores were evaluated with Visual Analog Scale (VAS) at the recovery room and postoperative 2, 4, 6, 12 and 24 hours. Time to first analgesic requirement, morphine consumption, incidence of nausea and vomiting, and sedation scores were recorded. VAS scores at rest and on movement in recovery room and postoperative 2 h were significantly lower Group BD than Group B (p

[1]  R. McCarthy,et al.  Perineural Dexamethasone to Improve Postoperative Analgesia with Peripheral Nerve Blocks: A Meta-Analysis of Randomized Controlled Trials , 2014, Pain research and treatment.

[2]  N. Bailard,et al.  Additives to local anesthetics for peripheral nerve blocks: Evidence, limitations, and recommendations. , 2014, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[3]  T. Gan,et al.  Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. , 2013, British journal of anaesthesia.

[4]  R. Brady,et al.  Clinical effectiveness of transversus abdominis plane (TAP) block in abdominal surgery: a systematic review and meta‐analysis , 2012, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[5]  F. Reinoso-Barbero,et al.  Successful ultrasound guidance for transversus abdominis plane blocks improves postoperative analgesia after open appendicectomy in children. , 2012, European journal of anaesthesiology.

[6]  K. Mahmoud,et al.  Effect of adding dexamethasone to bupivacaine on transversus abdominis plane block for abdominal hysterectomy: A prospective randomized controlled trial , 2012, Saudi journal of anaesthesia.

[7]  Kyoung Hoon Yim,et al.  Preemptive analgesic efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing gynecologic surgery via a transverse lower abdominal skin incision , 2011, Korean journal of anesthesiology.

[8]  A. Kurz,et al.  Effect of dexamethasone on the duration of interscalene nerve blocks with ropivacaine or bupivacaine. , 2011, British journal of anaesthesia.

[9]  N. Nader,et al.  Adjuvant dexamethasone with bupivacaine prolongs the duration of interscalene block: a prospective randomized trial , 2011, Journal of Anesthesia.

[10]  P. L. Petersen,et al.  The transversus abdominis plane block: a valuable option for postoperative analgesia? A topical review , 2010, Acta anaesthesiologica Scandinavica.

[11]  J. Laffey,et al.  The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy , 2008, Anesthesia and analgesia.

[12]  S. Singh,et al.  Transversus abdominis plane block for laparoscopic surgery. , 2008, British journal of anaesthesia.

[13]  J. Laffey,et al.  The Analgesic Efficacy of Transversus Abdominis Plane Block After Abdominal Surgery: A Prospective Randomized Controlled Trial , 2007, Anesthesia and analgesia.

[14]  B. O'donnell The Transversus Abdominis Plane (TAP) Block in Open Retropubic Prostatectomy , 2006, Regional Anesthesia & Pain Medicine.

[15]  H. Koçoğlu,et al.  Dexamethasone added to levobupivacaine in ultrasound-guided tranversus abdominis plain block increased the duration of postoperative analgesia after caesarean section: a randomized, double blind, controlled trial. , 2014, European review for medical and pharmacological sciences.