An extended diffraction-enhanced imaging method for implementing multiple-image radiography

Diffraction-enhanced imaging (DEI) is an analyser-based x-ray imaging method that produces separate images depicting the projected x-ray absorption and refractive properties of an object. Because the imaging model of DEI does not account for ultra-small-angle x-ray scattering (USAXS), the images produced in DEI can contain artefacts and inaccuracies in medical imaging applications. In this work, we investigate an extended DEI method for concurrent reconstruction of three images that depict an object's projected x-ray absorption, refraction and USAXS properties. The extended DEI method can be viewed as an implementation of the recently proposed multiple-image radiography paradigm. Validation studies are conducted by use of computer-simulated and synchrotron measurement data.

[1]  E Castelli,et al.  Mammography with synchrotron radiation: phase-detection techniques. , 2000, Radiology.

[2]  Paola Coan,et al.  A method to extract quantitative information in analyzer-based x-ray phase contrast imaging , 2003 .

[3]  Yongyi Yang,et al.  Preliminary investigation of a multiple-image radiography method , 2002, Proceedings IEEE International Symposium on Biomedical Imaging.

[4]  Jun Li,et al.  A computed tomography implementation of multiple-image radiography. , 2006, Medical physics.

[5]  Jun Li,et al.  Multiple‐image radiography for human soft tissue , 2006, Journal of anatomy.

[6]  E. Pisano,et al.  Diffraction enhanced x-ray imaging. , 1997, Physics in medicine and biology.

[7]  A. Bravin,et al.  Exploiting the x-ray refraction contrast with an analyser: the state of the art , 2003 .

[8]  Zhong Zhong,et al.  Measurement of image contrast using diffraction enhanced imaging. , 2003, Physics in medicine and biology.

[9]  B. L. Henke,et al.  X-Ray Interactions: Photoabsorption, Scattering, Transmission, and Reflection at E = 50-30,000 eV, Z = 1-92 , 1993 .

[10]  Paola Coan,et al.  Phase-contrast X-ray imaging combining free space propagation and Bragg diffraction. , 2005, Journal of synchrotron radiation.

[11]  Miles N. Wernick,et al.  Extraction of extinction, refraction and absorption properties in diffraction enhanced imaging , 2003 .

[12]  Timur E. Gureyev,et al.  Quantitative diffraction-enhanced x-ray imaging of weak objects , 2004 .

[13]  Zhong Zhong,et al.  Improved image contrast of calcifications in breast tissue specimens using diffraction enhanced imaging. , 2004, Physics in medicine and biology.

[14]  R. Lewis,et al.  Medical phase contrast x-ray imaging: current status and future prospects. , 2004, Physics in medicine and biology.

[15]  Luigi Rigon,et al.  A new DEI algorithm capable of investigating sub-pixel structures , 2003 .

[16]  William Thomlinson,et al.  Implementation of diffraction-enhanced imaging experiments: at the NSLS and APS , 2000 .

[17]  Timur E. Gureyev,et al.  Regimes of X-ray phase-contrast imaging with perfect crystals , 1997 .

[18]  E Castelli,et al.  Low-dose phase contrast x-ray medical imaging. , 1998, Physics in medicine and biology.

[19]  E. Pisano,et al.  Human breast cancer specimens: diffraction-enhanced imaging with histologic correlation--improved conspicuity of lesion detail compared with digital radiography. , 2000, Radiology.

[20]  Jovan G. Brankov,et al.  Noise and sampling analysis for multiple-image radiography , 2006, 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006..

[21]  David M Paganin,et al.  Analyser-based mammography using single-image reconstruction. , 2005, Physics in medicine and biology.

[22]  M. Wernick,et al.  A physical model of multiple-image radiography , 2006, Physics in medicine and biology.

[23]  Dean Chapman,et al.  Recent advances in synchrotron radiation medical research , 2005 .

[24]  Patrick J. La Rivière,et al.  Penalized-likelihood sinogram restoration for computed tomography , 2006, IEEE Transactions on Medical Imaging.

[25]  John R Davis,et al.  A variant on the geometrical optics approximation in diffraction enhanced tomography , 2001 .

[26]  N. Galatsanos,et al.  Multiple-image radiography. , 2003, Physics in medicine and biology.

[27]  S. Fiedler,et al.  Imaging lobular breast carcinoma: comparison of synchrotron radiation DEI-CT technique with clinical CT, mammography and histology. , 2004, Physics in medicine and biology.