Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability

Key Points • GOLM1 is significantly upregulated in ALK+ ALCL by nucleophosmin-ALK through AKT/mTOR/miR-145.• GOLM1 suppressed ALCL cells' apoptosis by prolonging B-cell lymphoma-extra large protein's stability and promoting ALK+ ALCL’s progression.