Low-intensity pulsed ultrasound inhibits messenger RNA expression of matrix metalloproteinase-13 induced by interleukin-1β in chondrocytes in an intensity-dependent manner.

[1]  Daxin Wang,et al.  Effect of Low-Intensity Pulsed Ultrasound on MMP-13 and MAPKs Signaling Pathway in Rabbit Knee Osteoarthritis , 2011, Cell Biochemistry and Biophysics.

[2]  B. Wolf,et al.  The effect of irrigation solution at different temperatures on articular cartilage metabolism. , 2011, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[3]  W. Maloney,et al.  Effects of intermittent hydrostatic pressure and BMP‐2 on osteoarthritic human chondrocyte metabolism in vitro , 2011, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[4]  H. Sun,et al.  Physiological loading of joints prevents cartilage degradation through CITED2 , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[5]  H. Sun Mechanical loading, cartilage degradation, and arthritis , 2010, Annals of the New York Academy of Sciences.

[6]  Dan L. Bader,et al.  The potential of pulsed low intensity ultrasound to stimulate chondrocytes matrix synthesis in agarose and monolayer cultures , 2010, Medical & Biological Engineering & Computing.

[7]  D. Saris,et al.  Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection , 2010, Arthritis research & therapy.

[8]  H. Sun,et al.  Matrix metalloproteinase-3 in articular cartilage is upregulated by joint immobilization and suppressed by passive joint motion. , 2010, Matrix biology : journal of the International Society for Matrix Biology.

[9]  F. Guilak,et al.  Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1. , 2010, Osteoarthritis and cartilage.

[10]  R G Spencer,et al.  Modification of osteoarthritis in the guinea pig with pulsed low-intensity ultrasound treatment. , 2010, Osteoarthritis and cartilage.

[11]  Emil H Schemitsch,et al.  Ultrasound for Fracture Healing: Current Evidence , 2010, Journal of orthopaedic trauma.

[12]  Kazuo Kaneko,et al.  Low‐intensity pulsed ultrasound (LIPUS) increases the articular cartilage type II collagen in a rat osteoarthritis model , 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[13]  Nicola Maffulli,et al.  The effects of LIPUS on soft-tissue healing: a review of literature. , 2008, British medical bulletin.

[14]  C. M. Korstjens,et al.  Low-intensity pulsed ultrasound affects human articular chondrocytes in vitro , 2008, Medical & Biological Engineering & Computing.

[15]  I. Aoki,et al.  Low-intensity pulsed ultrasound activates the phosphatidylinositol 3 kinase/Akt pathway and stimulates the growth of chondrocytes in three-dimensional cultures: a basic science study , 2008, Arthritis research & therapy.

[16]  H. Sun,et al.  Coordinate Regulation of IL-1β and MMP-13 in Rat Tendons Following Subrupture Fatigue Damage , 2008, Clinical orthopaedics and related research.

[17]  J. A. Evans,et al.  Can ultrasound propagate in the joint space of a human knee? , 2007, Ultrasound in medicine & biology.

[18]  B. Min,et al.  Mechanotransduction pathways of low-intensity ultrasound in C-28/I2 human chondrocyte cell line , 2007, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[19]  Kwideok Park,et al.  Therapeutic ultrasound effects on interleukin-1beta stimulated cartilage construct in vitro. , 2007, Ultrasound in medicine & biology.

[20]  R. Gassner,et al.  Biomechanical Signals Suppress Proinflammatory Responses in Cartilage: Early Events in Experimental Antigen-Induced Arthritis1 , 2006, The Journal of Immunology.

[21]  Byung Hyune Choi,et al.  Low-intensity ultrasound stimulates the viability and matrix gene expression of human articular chondrocytes in alginate bead culture. , 2006, Journal of biomedical materials research. Part A.

[22]  J. Deschner,et al.  Regulation of matrix metalloproteinase expression by dynamic tensile strain in rat fibrochondrocytes. , 2006, Osteoarthritis and cartilage.

[23]  B. Choi,et al.  Effects of low‐intensity ultrasound (LIUS) stimulation on human cartilage explants , 2006, Scandinavian journal of rheumatology.

[24]  Kwok-Sui Leung,et al.  Lack of Efficacy of Low-Intensity Pulsed Ultrasound on Prevention of Postmenopausal Bone Loss Evaluated at the Distal Radius in Older Chinese Women , 2004, Clinical orthopaedics and related research.

[25]  Z. Werb,et al.  Regulation of matrix biology by matrix metalloproteinases. , 2004, Current opinion in cell biology.

[26]  S. Yerby,et al.  Intermittent hydrostatic pressure inhibits matrix metalloproteinase and pro-inflammatory mediator release from human osteoarthritic chondrocytes in vitro. , 2004, Osteoarthritis and cartilage.

[27]  H. Sun,et al.  CITED2-mediated Regulation of MMP-1 and MMP-13 in Human Chondrocytes under Flow Shear* , 2003, Journal of Biological Chemistry.

[28]  R. Spencer,et al.  The effects of pulsed low-intensity ultrasound on chondrocyte viability, proliferation, gene expression and matrix production. , 2003, Ultrasound in medicine & biology.

[29]  A. Hollander,et al.  Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach. , 2003, Arthritis and rheumatism.

[30]  E B Hunziker,et al.  Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. , 2002, Osteoarthritis and cartilage.

[31]  Hiroki Yokota,et al.  Reduction of cytokine-induced expression and activity of MMP-1 and MMP-13 by mechanical strain in MH7A rheumatoid synovial cells. , 2002, Matrix biology : journal of the International Society for Matrix Biology.

[32]  Y. Harada,et al.  Low‐Intensity Pulsed Ultrasound Accelerates Rat Femoral Fracture Healing by Acting on the Various Cellular Reactions in the Fracture Callus , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[33]  H. Yokota,et al.  Altered mRNA level of matrix metalloproteinase-13 in MH7A synovial cells under mechanical loading and unloading. , 2001, Bone.

[34]  R. Gassner,et al.  Cyclic tensile strain suppresses catabolic effects of interleukin-1beta in fibrochondrocytes from the temporomandibular joint. , 2001, Arthritis and rheumatism.

[35]  Y. Kato,et al.  The effects of high magnitude cyclic tensile load on cartilage matrix metabolism in cultured chondrocytes. , 2000, European journal of cell biology.

[36]  D. Salter,et al.  Mechanotransduction via integrins and interleukin-4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes. , 2000, Arthritis and rheumatism.

[37]  J F Greenleaf,et al.  Low‐intensity ultrasound stimulates proteoglycan synthesis in rat chondrocytes by increasing aggrecan gene expression , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[38]  M. Takigawa,et al.  Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1. , 1999, Journal of biochemistry.

[39]  J. Pelletier,et al.  Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. , 1989, The Journal of clinical investigation.

[40]  M. Bhargava,et al.  Mechanical load inhibits IL-1 induced matrix degradation in articular cartilage. , 2010, Osteoarthritis and cartilage.

[41]  Emma J Blain,et al.  Mechanical regulation of matrix metalloproteinases. , 2007, Frontiers in bioscience : a journal and virtual library.

[42]  H. Akiyama,et al.  Transforming growth factor-beta1 mediates the effects of low-intensity pulsed ultrasound in chondrocytes. , 2005, Ultrasound in medicine & biology.

[43]  R F Kilcoyne,et al.  Acceleration of tibial fracture-healing by non-invasive, low-intensity pulsed ultrasound. , 1994, The Journal of bone and joint surgery. American volume.

[44]  M. Sporn,et al.  Transforming Growth Factor , 1990 .