Cutaneous presentation of recurrence of lymphoepithelioid T‐cell lymphoma (Lennert's lymphoma)

Lennert's lymphoma (LL) is a T‐cell lymphoma characterized by the presence of atypical T lymphocytes, admixed with histiocytes and epithelioid granulomas. Patients present with superficial lymph node involvement, mainly in the cervical areas; thoracic adenopathies and involvement of deep abdominal lymph nodes are rare. Cutaneous involvement is infrequent, reported to occur in only 4–11% of patients, and even rarer is the onset of cutaneous lesions as first sign of a recurrence. We report a female patient who presented with papules and nodules on the trunk and upper limbs as the first manifestation of recurrent LL.

[1]  Antonia Gutiérrez Martín,et al.  Lymphoepithelioid Cell Lymphoma (Lennert’s Lymphoma) , 2004, Acta Cytologica.

[2]  H. Kerl,et al.  Cutaneous Lymphomas With Prominent Granulomatous Reaction: A Potential Pitfall in the Histopathologic Diagnosis of Cutaneous T- and B-Cell Lymphomas , 2002, The American journal of surgical pathology.

[3]  Y. Kagami,et al.  Lennert's Lymphoma: A Variant of Cytotoxic T-Cell Lymphoma? , 2000, The American journal of surgical pathology.

[4]  R. Chalmers,et al.  Lymphoepithelioid cell lymphoma (Lennert's lymphoma) presenting as atypical granuloma annulare. , 2000, The British journal of dermatology.

[5]  M. Engelhard,et al.  Lymphoepithelioid cell lymphoma (Lennert's lymphoma): clinical features derived from analysis of 108 cases. , 1993 .

[6]  K. Lennert,et al.  Cutaneous Lymphoepithelioid Lymphoma (Lennert's Lymphoma): Combined Immunohistological, Ultrastructural, and DNA‐Flow-Cytometric Analysis , 1989, The American Journal of dermatopathology.

[7]  M. Harkey,et al.  Cutaneous involvement in Lennert's lymphoma. , 1980, Archives of dermatology.

[8]  B. Nathwani,et al.  So‐called “Lennert's Lymphoma”. Is it a clinicopathologic entity? , 1980, Cancer.

[9]  R. Warnke,et al.  Malignant lymphoma with a high content of epithelioid histiocytes. A distinct clinicopathologic entity and a form of so‐called „Lennert's Lymphoma”︁ , 1978, Cancer.

[10]  K. Lennert,et al.  Lymphogranulomatosen mit konstant hohem Epitheloidzellgehalt , 1968, Virchows Archiv A.