Fusion protein of TLR5-ligand and allergen potentiates activation and IL-10 secretion in murine myeloid DC.

[1]  M. Akdiş Immune tolerance in allergy. , 2009, Current opinion in immunology.

[2]  T. Bieber,et al.  Dendritic cells as potential targets for mucosal immunotherapy , 2009, Current opinion in allergy and clinical immunology.

[3]  John T. Bates,et al.  Direct Stimulation of tlr5+/+ CD11c+ Cells Is Necessary for the Adjuvant Activity of Flagellin1 , 2009, The Journal of Immunology.

[4]  C. Akdis,et al.  Mechanisms and treatment of allergic disease in the big picture of regulatory T cells. , 2009, The Journal of allergy and clinical immunology.

[5]  S. Akira,et al.  Excessive CpG 1668 stimulation triggers IL‐10 production by cDC that inhibits IFN‐α responses by pDC , 2008, European journal of immunology.

[6]  W. Stoorvogel,et al.  Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells , 2008, Nature Immunology.

[7]  Hiroshi Kiyono,et al.  Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5 , 2008, Nature Immunology.

[8]  C. Hawrylowicz,et al.  Strategies for use of IL‐10 or its antagonists in human disease , 2008, Immunological reviews.

[9]  S. Holgate,et al.  Treatment strategies for allergy and asthma , 2008, Nature Reviews Immunology.

[10]  R. K. Evans,et al.  Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin. , 2008, Vaccine.

[11]  Young Ran Kim,et al.  Inhibition of Airway Allergic Disease by Co-Administration of Flagellin with Allergen , 2008, Journal of Clinical Immunology.

[12]  J. Bell,et al.  Matrix protein mediated shutdown of host cell metabolism limits vesicular stomatitis virus-induced interferon-alpha responses to plasmacytoid dendritic cells. , 2008, Immunobiology.

[13]  S. H. van der Burg,et al.  Distinct Uptake Mechanisms but Similar Intracellular Processing of Two Different Toll-like Receptor Ligand-Peptide Conjugates in Dendritic Cells* , 2007, Journal of Biological Chemistry.

[14]  Y. Huang,et al.  A West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity. , 2007, The Journal of infectious diseases.

[15]  Y. Huang,et al.  Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. , 2007, Vaccine.

[16]  J. Rolland,et al.  The peanut allergy epidemic: allergen molecular characterisation and prospects for specific therapy , 2007, Expert Reviews in Molecular Medicine.

[17]  C. Coban,et al.  Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells , 2006, Nature Immunology.

[18]  C. Akdis,et al.  T regulatory cells in allergy. , 2006, Chemical immunology and allergy.

[19]  U. Wiedermann Prophylaxis and therapy of allergy by mucosal tolerance induction with recombinant allergens or allergen constructs. , 2005, Current drug targets. Inflammation and allergy.

[20]  T. Ben-Yedidia,et al.  Towards an Epitope-Based Human Vaccine for Influenza , 2005, Human vaccines.

[21]  D. Umetsu,et al.  Allergen immunotherapy with heat‐killed Listeria monocytogenes alleviates peanut and food‐induced anaphylaxis in dogs , 2005, Allergy.

[22]  P. Bhalla,et al.  Engineered allergens for immunotherapy , 2004, Current opinion in allergy and clinical immunology.

[23]  J. Sirard,et al.  Flagellin Promotes Myeloid Differentiation Factor 88-Dependent Development of Th2-Type Response1 , 2004, The Journal of Immunology.

[24]  J. Lustgarten,et al.  Flagellin Fusion Proteins as Adjuvants or Vaccines Induce Specific Immune Responses , 2004, Infection and Immunity.

[25]  H. Fiebig,et al.  Transition of recombinant allergens from bench to clinical application. , 2004, Methods.

[26]  S. Way,et al.  Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity , 2004, Cellular microbiology.

[27]  Hugh B Nicholas,et al.  Mathematically Complete Nucleotide and Protein Sequence Searching Using Ssearch , 2003, Current protocols in bioinformatics.

[28]  A. Aderem,et al.  Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility , 2003, Nature Immunology.

[29]  A. Aderem,et al.  The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells1 , 2003, The Journal of Immunology.

[30]  Marek Jutel,et al.  IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy , 2003, European journal of immunology.

[31]  A. Burks,et al.  Engineered Recombinant Peanut Protein and Heat-Killed Listeria monocytogenes Coadministration Protects Against Peanut-Induced Anaphylaxis in a Murine Model1 , 2003, The Journal of Immunology.

[32]  S. Akira,et al.  Critical Roles of Myeloid Differentiation Factor 88-Dependent Proinflammatory Cytokine Release in Early Phase Clearance of Listeria monocytogenes in Mice1 , 2002, The Journal of Immunology.

[33]  K. Smith,et al.  Toll-like receptor-5 and the innate immune response to bacterial flagellin. , 2002, Current topics in microbiology and immunology.

[34]  J. Sirard,et al.  Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[35]  D. Umetsu,et al.  Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen , 2001, Nature Immunology.

[36]  S. Akira,et al.  The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 , 2001, Nature.

[37]  G. Berry,et al.  Vaccination with Heat-Killed Listeria as Adjuvant Reverses Established Allergen-Induced Airway Hyperreactivity and Inflammation: Role of CD8+ T Cells and IL-181 , 2000, The Journal of Immunology.

[38]  C. Akdis,et al.  Mechanisms of allergen-specific immunotherapy. , 2007, The Journal of allergy and clinical immunology.

[39]  T. Ben-Yedidia,et al.  Intranasal administration of peptide vaccine protects human/mouse radiation chimera from influenza infection. , 1999, International immunology.

[40]  T. Ben-Yedidia,et al.  Effect of pre-existing carrier immunity on the efficacy of synthetic influenza vaccine. , 1998, Immunology letters.

[41]  D. Umetsu,et al.  Heat-killed Listeria monocytogenes as an adjuvant converts established murine Th2-dominated immune responses into Th1-dominated responses. , 1998, Journal of immunology.

[42]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.