Anatomy of the atrioventricular conduction system.

To the Editor: I am writing regarding the article by Racker and Kadish1 that appeared in a previous issue of Circulation . Their statement that “the atrioventricular (AV) node and AV bundle consist of myocardial fascicles, not myofibers”1 is inappropriate.2 Dorland’s Illustrated Medical Dictionary defines fascicle as “a small bundle or cluster, especially of nerve or muscle fibers.” The human conduction system has more collagenous connective tissue and elastic tissue than the surrounding myocardium, and this may be considered the hallmark of the conduction system histologically.2 Lev et al2 did not mention anything about nerves in their work cited by Racker and Kadish. Racker and Kadish’s interpretation of Figures 1 and 4 from the article by Lev et al2 needs further clarification.1 They state that “Lev et al’s Figure 1 partially overlooked the proximal AV bundle, as seen in schematic AV junction region tissue blocks.”1 This statement is inaccurate. Figure 1 …

[1]  A H Kadish,et al.  Proximal atrioventricular bundle, atrioventricular node, and distal atrioventricular bundle are distinct anatomic structures with unique histological characteristics and innervation. , 2000, Circulation.

[2]  A. Embi,et al.  Microtransection of the His bundle with laser radiation through a pervenous catheter: correlation of histologic and electrophysiologic data. , 1984, The American journal of cardiology.

[3]  K. Rosen,et al.  Sudden death caused by benign tumor of the atrioventricular node. , 1976, Archives of internal medicine.

[4]  D. K. Racker Sinoventricular Transmission in 10 mM K+ by Canine Atrioventricular Nodal Inputs: Superior Atrionodal Bundle and Proximal Atrioventricular Bundle , 1991, Circulation.

[5]  D. K. Racker The demonstration of intercellular coupling between cells of the canine distal AV bundle using lucifer yellow-CH and histological sections. , 1989, Journal of molecular and cellular cardiology.

[6]  M. Lev,et al.  A method for the histopathologic study of the atrioventricular node, bundle, and branches. , 1951, A.M.A. archives of pathology.

[7]  B F Hoffman,et al.  Anatomy of the Tricuspid Annulus Circumferential Myofibers as the Structural Basis for Atrial Flutter in a Canine Model , 1991, Circulation.

[8]  S. Huang,et al.  Closed chest catheter desiccation of the atrioventricular junction using radiofrequency energy--a new method of catheter ablation. , 1987, Journal of the American College of Cardiology.