Neuromuscular Blocking Properties of Dioxonium

The characteristics of the myoneural block caused by a new neuromuscuiar blocking agent, dioxonium (Dx), were evaluated in surgical patients. The force and the corresponding electromyogram (EMG) of the thumb adduction evoked by various modes of ulnar nerve stimuli were measured. Onset, maintenance and disappearance of blockade after sequential administration of Dx were compared with results obtained with d‐tubocurarine (dTc) or suxamethonium (Sx).