Frequency Multiplexed 2-Dimensional Sensor Array Based on Split-Ring Resonators for Organic Tissue Analysis

A frequency multiplexed 2-dimensional sensor array was developed using microstrip-line-excited split-ring resonators (SRRs). With the proposed structures, it is possible to spatially resolve the relative changes of the dielectric properties of a Material Under Test (MUT) in one and two dimensions. The SRRs are designed to have different resonant frequencies and are decoupled from each other. With these design characteristics, it is possible to track changes on the resonant frequency of individual SRR that will indicate the dielectric properties of the MUT around the ring and therefore its location within the array. The number of pixels of the dielectric image corresponds to the number of SRRs within the sensor. Several prototype sensors have been realized and tested with different MUT such as dielectric bricks, animal tissue and phantoms of human tissue to prove the concept.

[1]  Yingqing Xia,et al.  A Wireless Sensor Using Left-Handed Metamaterials , 2008, 2008 4th International Conference on Wireless Communications, Networking and Mobile Computing.

[2]  Peter R C Gascoyne,et al.  Dielectrophoretic Separation of Cancer Cells from Blood. , 1997, IEEE transactions on industry applications.

[3]  Manos M. Tentzeris,et al.  A novel passive wireless ultrasensitive RF temperature transducer for remote sensing , 2010, 2010 IEEE MTT-S International Microwave Symposium.

[4]  J. Bonache,et al.  Equivalent-circuit models for split-ring resonators and complementary split-ring resonators coupled to planar transmission lines , 2005, IEEE Transactions on Microwave Theory and Techniques.

[5]  Aastha Trehan NUMERICAL AND PHYSICAL MODELS FOR MICROWAVE BREAST IMAGING , 2009 .

[6]  J. Stiens,et al.  Sensing liquid properties using split-ring resonator in Mm-wave band , 2010, IECON 2010 - 36th Annual Conference on IEEE Industrial Electronics Society.

[7]  J.A. Schwartz,et al.  A three-dimensional dielectrophoretic particle focusing channel for microcytometry applications , 2005, Journal of Microelectromechanical Systems.

[8]  Rolf Jakoby,et al.  Sensor array based on split ring resonators for analysis of organic tissues , 2011, 2011 IEEE MTT-S International Microwave Symposium.

[9]  R. Pethig,et al.  Use of dielectrophoretic collection spectra for characterizing differences between normal and cancerous cells , 1992, Conference Record of the 1992 IEEE Industry Applications Society Annual Meeting.

[10]  S. Mashimo,et al.  Time domain reflectometry: measurement of free water in normal lung and pulmonary edema. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[11]  H. P. Schwan,et al.  Analysis of Dielectric Data: Experience Gained with Biological Materials , 1985, IEEE Transactions on Electrical Insulation.

[12]  O. Ramahi,et al.  Double Negative Metamaterials for Subsurface Detection , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[13]  H. Schwan Electrical properties of tissues and cell suspensions: mechanisms and models , 1994, Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[14]  Gonul Turhan-Sayan,et al.  Metamaterial sensor applications based on broadside-coupled SRR and V-Shaped resonator structures , 2011, 2011 IEEE International Symposium on Antennas and Propagation (APSURSI).

[15]  R. W. Lau,et al.  The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues. , 1996, Physics in medicine and biology.

[16]  T. Ramanathan,et al.  Electrical Properties of Biological Tissues - An Impedance Spectroscopy Study , 2006, 2006 IEEE Conference on Electrical Insulation and Dielectric Phenomena.

[17]  C. Puttlitz,et al.  Metamaterial-based wireless strain sensors , 2009 .

[18]  Brandon Santoni,et al.  Nested Metamaterials for Wireless Strain Sensing , 2010, IEEE Journal of Selected Topics in Quantum Electronics.

[19]  Peter R. C. Gascoyne,et al.  Dielectrophoresis-based sample handling in general-purpose programmable diagnostic instruments , 2004, Proceedings of the IEEE.

[20]  K. Foster,et al.  RF-field interactions with biological systems: Electrical properties and biophysical mechanisms , 1980, Proceedings of the IEEE.

[21]  J. Pendry,et al.  Magnetism from conductors and enhanced nonlinear phenomena , 1999 .