Determination of Polyphenol and Flavonoid Profiles and Testing the Antibacterial Effect of Acanthus longifolius Comparative with Vaccinium myrtillus

From our research we noticed that Acanthi balcanici herba (ABH) contains luteolin and quercetol and Myrtillus fructus (M-fr) contains chlorogenic acid, apigenol and rutoside. ABH has no antibacterial effect on any species tested, completely cancel the therapeutic effect of three drugs (amoxicillin + clavulanic acid, levofloxacin, amikacin) and have no significant effect on the other two antibiotics (cefotaxime and ceftazidime) when they are associated. All bacterial species were sensitive to M-fr and the extract has synergistic effect in combination with levoflaxacin, amikacin and cefotaxime.

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