BDNF/TrkB axis activation promotes epithelial–mesenchymal transition in idiopathic pulmonary fibrosis

[1]  C. Ruppert,et al.  Tissue remodelling in pulmonary fibrosis , 2017, Cell and Tissue Research.

[2]  Gerhard Christofori,et al.  Epithelial-mesenchymal transition (EMT) and metastasis: yes, no, maybe? , 2016, Current opinion in cell biology.

[3]  R. Toillon,et al.  Neurotrophin signaling in cancer stem cells , 2016, Cellular and Molecular Life Sciences.

[4]  R. Mancini,et al.  Genetic and Functional Analysis of Polymorphisms in the Human Dopamine Receptor and Transporter Genes in Small Cell Lung Cancer , 2016, Journal of cellular physiology.

[5]  C. Vancheri.  Idiopathic pulmonary fibrosis and cancer: do they really look similar? , 2015, BMC Medicine.

[6]  Shandra L. Protzko,et al.  An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline. , 2015, American journal of respiratory and critical care medicine.

[7]  S. Schwartz,et al.  EMT blockage strategies: Targeting Akt dependent mechanisms for breast cancer metastatic behaviour modulation. , 2015, Current gene therapy.

[8]  杨新杰.  Schwann cells promote EMT and the Schwann-like differentiation of salivary adenoid cystic carcinoma cells via the BDNF/TrkB axis , 2015 .

[9]  Lei Wang,et al.  BDNF mediated TrkB activation contributes to the EMT progression and the poor prognosis in human salivary adenoid cystic carcinoma. , 2015, Oral oncology.

[10]  B. Lin,et al.  NGF Accelerates Cutaneous Wound Healing by Promoting the Migration of Dermal Fibroblasts via the PI3K/Akt-Rac1-JNK and ERK Pathways , 2014, BioMed research international.

[11]  I. Martin,et al.  TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms , 2014, Development.

[12]  I. Martin,et al.  TGF-&bgr;-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms , 2014, Journal of Cell Science.

[13]  Samy Lamouille,et al.  Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.

[14]  C. Hogaboam,et al.  Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis , 2014, Front. Pharmacol..

[15]  W. Tian,et al.  Nerve growth factor exacerbates allergic lung inflammation and airway remodeling in a rat model of chronic asthma , 2013, Experimental and therapeutic medicine.

[16]  D. Kamp,et al.  Oxidative stress and pulmonary fibrosis. , 2013, Biochimica et biophysica acta.

[17]  L. Fattore,et al.  TrkB is responsible for EMT transition in malignant pleural effusions derived cultures from adenocarcinoma of the lung , 2013, Cell cycle.

[18]  P. Wolters,et al.  Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis. , 2011, American journal of physiology. Lung cellular and molecular physiology.

[19]  Takeshi Johkoh,et al.  American Thoracic Society Documents An Official ATS / ERS / JRS / ALAT Statement : Idiopathic Pulmonary Fibrosis : Evidence-based Guidelines for Diagnosis and Management , 2011 .

[20]  W. Seeger,et al.  Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis. , 2011, American journal of respiratory cell and molecular biology.

[21]  H. Chapman,et al.  Epithelial-mesenchymal interactions in pulmonary fibrosis. , 2011, Annual review of physiology.

[22]  H. Riechelmann,et al.  Fibroblasts produce brain-derived neurotrophic factor and induce mesenchymal transition of oral tumor cells , 2011, Oral oncology.

[23]  Richard J Martin,et al.  Neurotrophins in lung health and disease , 2010, Expert review of respiratory medicine.

[24]  D. Yu,et al.  TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma , 2010, Oncogene.

[25]  H. Iwasaki,et al.  Epithelial–mesenchymal transition in human lungs with usual interstitial pneumonia: Quantitative immunohistochemistry , 2010, Pathology international.

[26]  P. Pérez-Piñera,et al.  TrkB is necessary for the normal development of the lung , 2009, Respiratory Physiology & Neurobiology.

[27]  Ji-Ying Song,et al.  A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis , 2009, Molecular and Cellular Biology.

[28]  R. D. du Bois,et al.  Increased pulmonary neurotrophin protein expression in idiopathic interstitial pneumonias. , 2007, Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG.

[29]  L. Reichardt,et al.  Neurotrophin-regulated signalling pathways , 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

[30]  D. Sheppard,et al.  Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix , 2006, Proceedings of the National Academy of Sciences.

[31]  P. Pérez-Piñera,et al.  The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas , 2006, Molecular and Cellular Biochemistry.

[32]  M. Nieto,et al.  The Snail genes as inducers of cell movement and survival: implications in development and cancer , 2005, Development.

[33]  C. McCulloch,et al.  Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. , 2004, The American journal of pathology.

[34]  S. Shapiro,et al.  The bone marrow leaves its scar: new concepts in pulmonary fibrosis. , 2004, The Journal of clinical investigation.

[35]  C. McCulloch,et al.  Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. , 2004, The American journal of pathology.

[36]  P. Thompson,et al.  Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation. , 2003, The American journal of pathology.

[37]  F. Amenta,et al.  Neurotrophins and neurotrophin receptors in human lung cancer. , 2001, American journal of respiratory cell and molecular biology.

[38]  J. Peyrat,et al.  Nerve Growth Factor Stimulates Proliferation and Survival of Human Breast Cancer Cells through Two Distinct Signaling Pathways* , 2001, The Journal of Biological Chemistry.

[39]  E. Huang,et al.  Neurotrophins: roles in neuronal development and function. , 2001, Annual review of neuroscience.

[40]  M. Suko,et al.  Increased IL‐6 and IL‐8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters , 1997, Clinical and experimental immunology.

[41]  Y. Barde,et al.  Physiology of the neurotrophins. , 1996, Annual review of neuroscience.