Neocortical and Thalamic Spread of Amygdala Kindled Seizures

Summary:  Purpose: Amygdala kindling is an epilepsy model involving long‐term network plasticity in the nervous system. In this model, repeated weak stimulation of the amygdala eventually leads to severe motor seizures. The mechanisms for worsening behavioral seizures, and the possible role of enhanced connectivity between the amygdala and other structures have not been thoroughly investigated.

[1]  J. Gotman Measurement of small time differences between EEG channels: method and application to epileptic seizure propagation. , 1983, Electroencephalography and clinical neurophysiology.

[2]  D. Mcintyre,et al.  Cortical spreading depression reversibly disrupts convulsive motor seizure expression in amygdala-kindled rats , 1999, Neuroscience.

[3]  M. Brazier Interactions of Deep Structures during Seizures in Man , 1972 .

[4]  R. Racine,et al.  Modification of seizure activity by electrical stimulation. 3. Mechanisms. , 1972, Electroencephalography and clinical neurophysiology.

[5]  M. Hasselmo What is the function of hippocampal theta rhythm?—Linking behavioral data to phasic properties of field potential and unit recording data , 2005, Hippocampus.

[6]  J. McNamara Kindling: An animal model of complex partial epilepsy , 1984, Annals of neurology.

[7]  P. Mangan,et al.  The Midline Thalamus: Alterations and a Potential Role in Limbic Epilepsy , 2001, Epilepsia.

[8]  Dynamic propagation of seizure discharges in the motor cortical kindling. , 1983, The International journal of neuroscience.

[9]  A. Handforth,et al.  Functional [14C]2-deoxyglucose mapping of progressive states of status epilepticus induced by amygdala stimulation in rat , 1988, Brain Research.

[10]  J. Fell,et al.  Rhinal–hippocampal theta coherence during declarative memory formation: interaction with gamma synchronization? , 2003, The European journal of neuroscience.

[11]  Ning Wu,et al.  A New Model , 1998 .

[12]  C. Decarli,et al.  Extratemporal atrophy in patients with complex partial seizures of left temporal origin , 1998, Annals of neurology.

[13]  M. E. Corcoran,et al.  Frontal Lobe and Kindling in the Rat , 1975, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[14]  R. Duckrow,et al.  Regional coherence and the transfer of ictal activity during seizure onset in the medial temporal lobe. , 1992, Electroencephalography and clinical neurophysiology.

[15]  J. Milton,et al.  Identification of the sensory/motor area and pathologic regions using ECoG coherence. , 1998, Electroencephalography and clinical neurophysiology.

[16]  M. Brazier Spread of seizure discharges in epilepsy: anatomical and electrophysiological considerations. , 1972, Experimental neurology.

[17]  J H Margerison,et al.  Epilepsy and the temporal lobes. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. , 1966, Brain : a journal of neurology.

[18]  K. Gale,et al.  Subcortical structures and pathways involved in convulsive seizure generation. , 1992, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[19]  G. V. Goddard,et al.  Development of Epileptic Seizures through Brain Stimulation at Low Intensity , 1967, Nature.

[20]  D. Cain Long-term potentiation and kindling: How similar are the mechanisms? , 1989, Trends in Neurosciences.

[21]  D. Mcintyre Split-Brain Rat: Transfer and Interference of Kindled Amygdala Convulsions , 1975, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[22]  L. Brown,et al.  Anatomical correlates of electrical and behavioral events related to amygdaloid kindling , 1978, Annals of neurology.

[23]  S. S. Yoon,et al.  Limbic system abnormalities associated with mesial temporal sclerosis: a model of chronic cerebral changes due to seizures. , 1997, Radiographics : a review publication of the Radiological Society of North America, Inc.

[24]  R. Racine,et al.  Piriform cortex efferents to the entorhinal cortex in vivo: kindling‐induced potentiation and the enhancement of long‐term potentiation by low‐frequency piriform cortex or medial septal stimulation , 1997, Hippocampus.

[25]  R. Racine Modification of seizure activity by electrical stimulation: cortical areas. , 1975, Electroencephalography and clinical neurophysiology.

[26]  L. Swanson The Rat Brain in Stereotaxic Coordinates, George Paxinos, Charles Watson (Eds.). Academic Press, San Diego, CA (1982), vii + 153, $35.00, ISBN: 0 125 47620 5 , 1984 .

[27]  Margaret Fahnestock,et al.  Kindling and status epilepticus models of epilepsy: rewiring the brain , 2004, Progress in Neurobiology.

[28]  D. Mcintyre,et al.  A new model of partial status epilepticus based on kindling , 1982, Brain Research.

[29]  T. Bullock,et al.  Temporal fluctuations in coherence of brain waves. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[30]  M. E. Corcoran,et al.  Role of the Forebrain Commissures in Amygdaloid Kindling in Rats , 1978, Epilepsia.

[31]  T. Bullock,et al.  EEG coherence has structure in the millimeter domain: subdural and hippocampal recordings from epileptic patients. , 1995, Electroencephalography and clinical neurophysiology.

[32]  E. Bertram Functional Anatomy of Spontaneous Seizures in a Rat Model of Limbic Epilepsy , 1997, Epilepsia.

[33]  E. Bertram,et al.  The Pathological Substrate of Limbic Epilepsy: Neuronal Loss in the Medial Dorsal Thalamic Nucleus as the Consistent Change , 2000, Epilepsia.

[34]  Power spectral analysis of electroencephalographic activity in kindled rats , 1986, Experimental Neurology.

[35]  Mary A.B. Brazier,et al.  Electrical Seizure Discharges Within the Human Brain: The Problem of Spread , 1973 .

[36]  Y. Hirayasu,et al.  N‐Methyl‐d‐Aspartate Injection Into the Massa Intermedia Facilitates Development of Limbic Kindling in Rats , 1992, Epilepsia.

[37]  R. Racine,et al.  Modification of seizure activity by electrical stimulation. II. Motor seizure. , 1972, Electroencephalography and clinical neurophysiology.

[38]  R. Vertes Hippocampal theta rhythm: A tag for short‐term memory , 2005, Hippocampus.

[39]  R. Stickgold,et al.  Sleep-Dependent θ Oscillations in the Human Hippocampus and Neocortex , 2003, The Journal of Neuroscience.

[40]  J Gotman,et al.  Interhemispheric interactions in seizures of focal onset: data from human intracranial recordings. , 1987, Electroencephalography and clinical neurophysiology.

[41]  J. Lisman The theta/gamma discrete phase code occuring during the hippocampal phase precession may be a more general brain coding scheme , 2005, Hippocampus.

[42]  F. D. Silva,et al.  Propagation of seizure activity in kindled dogs. , 1983 .

[43]  Colin Studholme,et al.  Positive and negative network correlations in temporal lobe epilepsy. , 2004, Cerebral cortex.

[44]  K. Ono,et al.  A new approach to the reactive afterdischarge in the development of kindling. , 1981, The International journal of neuroscience.

[45]  J P Lieb,et al.  Inter-hemispheric propagation of human mesial temporal lobe seizures: a coherence/phase analysis. , 1987, Electroencephalography and clinical neurophysiology.

[46]  R. Racine Modification of seizure activity by electrical stimulation. I. After-discharge threshold. , 1972, Electroencephalography and clinical neurophysiology.

[47]  F. H. Lopes da Silva,et al.  Propagation of seizure activity in kindled dogs. , 1983, Electroencephalography and clinical neurophysiology.

[48]  J. N. Hayward,et al.  Kindling in spontaneous hypertensive rats , 1989, Brain Research.

[49]  Y. Ryu,et al.  Ipsilateral thalamic hypoperfusion on interictal SPECT in temporal lobe epilepsy. , 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[50]  J. Gotman,et al.  Amygdala-hippocampus relationships in temporal lobe seizures: a phase-coherence study , 1996, Epilepsy Research.

[51]  P Naitoh,et al.  Intra-hemispheric phase relationships during self-regulated alpha activity. , 1974, Electroencephalography and clinical neurophysiology.

[52]  W. J. Williams,et al.  Measuring the coherence of intracranial electroencephalograms , 1999, Clinical Neurophysiology.

[53]  J Gotman,et al.  Seizure recognition and analysis. , 1985, Electroencephalography and clinical neurophysiology. Supplement.

[54]  E. Hargreaves,et al.  An examination of the relations between hippocampal long‐term potentiation, kindling, afterdischarge, and place learning in the water maze , 1993, Hippocampus.

[55]  D. Mcintyre,et al.  Kindling: some old and some new , 2002, Epilepsy Research.

[56]  D. G. Watts,et al.  Spectral analysis and its applications , 1968 .

[57]  G. Buzsáki Theta rhythm of navigation: Link between path integration and landmark navigation, episodic and semantic memory , 2005, Hippocampus.

[58]  G. V. Goddard,et al.  A permanent change in brain function resulting from daily electrical stimulation. , 1969, Experimental neurology.

[59]  J. Mazziotta,et al.  Interictal metabolic anatomy of mesial temporal lobe epilepsy. , 1993, Archives of neurology.