Cell cycle regulation by the Wee1 Inhibitor PD0166285, Pyrido [2,3-d] pyimidine, in the B16 mouse melanoma cell line
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H. Koga | T. Ueno | M. Sata | Toru Nakamura | K. Selvendiran | T. Torimura | M. Sakamoto | O. Hashimoto | M. Shinkawa
[1] P. Jackson,et al. Translational Unmasking of Emi2 Directs Cytostatic Factor Arrest in Meiosis II , 2007, Cell cycle.
[2] R. Assoian,et al. Effects of Rho Kinase and Actin Stress Fibers on Sustained Extracellular Signal-Regulated Kinase Activity and Activation of G1 Phase Cyclin-Dependent Kinases , 2006, Molecular and Cellular Biology.
[3] T. Ueno,et al. Suppression of transforming growth factor-beta results in upregulation of transcription of regeneration factors after chronic liver injury. , 2004, Journal of hepatology.
[4] Ashok Kumar,et al. Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac‐1 GTPase, and NF‐kB transcription factor , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[5] M. Moasser,et al. S-phase Inhibition of Cell Cycle Progression by a Novel Class of Pyridopyrimidine Tyrosine Kinase Inhibitors , 2004, Cell cycle.
[6] A. Konagaya,et al. An Effective Method for Selecting siRNA Target Sequences in Mammalian Cells , 2004, Cell cycle.
[7] T. Kawabe. G2 checkpoint abrogators as anticancer drugs. , 2004, Molecular cancer therapeutics.
[8] Nathan H. Lents,et al. Expression of Cyclin E Renders Cyclin D-CDK4 Dispensable for Inactivation of the Retinoblastoma Tumor Suppressor Protein, Activation of E2F, and G1-S Phase Progression* , 2004, Journal of Biological Chemistry.
[9] Richard G. W. Anderson,et al. Integrins Regulate Rac Targeting by Internalization of Membrane Domains , 2004, Science.
[10] D. Schlaepfer,et al. Localized Stabilization of Microtubules by Integrin- and FAK-Facilitated Rho Signaling , 2004, Science.
[11] J. Guan. Integrins, Rafts, Rac, and Rho , 2004, Science.
[12] Krister Wennerberg,et al. Rho and Rac Take Center Stage , 2004, Cell.
[13] G. Borisy,et al. Cell Migration: Integrating Signals from Front to Back , 2003, Science.
[14] K. Shokat,et al. Targets of the cyclin-dependent kinase Cdk1 , 2003, Nature.
[15] R. Assoian,et al. Nuclear translocation of LIM kinase mediates Rho-Rho kinase regulation of cyclin D1 expression. , 2003, Developmental cell.
[16] J. Zalvide,et al. Inhibition of Cdk4 Activity Enhances Translation of p27 kip1 in Quiescent Rb-negative Cells* , 2003, The Journal of Biological Chemistry.
[17] H. Koga,et al. Inhibition of proteasome‐dependent degradation of Wee1 in G2‐arrested Hep3B cells by TGFβ1 , 2003, Molecular carcinogenesis.
[18] A. Hall,et al. Rho GTPases in cell biology , 2002, Nature.
[19] Martin A. Schwartz,et al. Networks and crosstalk: integrin signalling spreads , 2002, Nature Cell Biology.
[20] T. Lawrence,et al. Wild-Type TP53 Inhibits G2-Phase Checkpoint Abrogation and Radiosensitization Induced by PD0166285, a WEE1 Kinase Inhibitor , 2002, Radiation research.
[21] R. Hollingsworth,et al. Apoptotic Regulation by the Crk Adapter Protein Mediated by Interactions with Wee1 and Crm1/Exportin , 2002, Molecular and Cellular Biology.
[22] J. Gutkind,et al. Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-κB , 2002, Oncogene.
[23] Jun Yu Li,et al. Radiosensitization of p53 mutant cells by PD0166285, a novel G(2) checkpoint abrogator. , 2001, Cancer research.
[24] M. A. Moseley,et al. Wee1-Regulated Apoptosis Mediated by the Crk Adaptor Protein in Xenopus Egg Extracts , 2000, The Journal of cell biology.
[25] T. Vanden Hoek,et al. Characterization of a Rac1 Signaling Pathway to Cyclin D1 Expression in Airway Smooth Muscle Cells* , 1999, The Journal of Biological Chemistry.
[26] H. Piwnica-Worms,et al. Overproduction of Human Myt1 Kinase Induces a G2 Cell Cycle Delay by Interfering with the Intracellular Trafficking of Cdc2-Cyclin B1 Complexes , 1999, Molecular and Cellular Biology.
[27] J. Newport,et al. Coupling of mitosis to the completion of S phase through Cdc34-mediated degradation of Wee1. , 1998, Science.
[28] D. Lew,et al. Control of Swe1p degradation by the morphogenesis checkpoint , 1998, The EMBO journal.
[29] P. Russell,et al. Checkpoints on the road to mitosis. , 1998, Trends in biochemical sciences.
[30] P. Russell,et al. Replication checkpoint enforced by kinases Cds1 and Chk1. , 1998, Science.
[31] P. Nurse. Checkpoint Pathways Come of Age , 1997, Cell.
[32] T. Hunter,et al. The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. , 1997, Cancer research.
[33] J. Harper,et al. Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. , 1997, Molecular biology of the cell.
[34] P. Nurse,et al. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation , 1997, The EMBO journal.
[35] C. Sherr. Cancer Cell Cycles , 1996, Science.
[36] H. Lane,et al. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo , 1995, Cell.
[37] V. Baldin,et al. Subcellular localisation of human wee1 kinase is regulated during the cell cycle. , 1995, Journal of cell science.
[38] N Watanabe,et al. Regulation of the human WEE1Hu CDK tyrosine 15‐kinase during the cell cycle. , 1995, The EMBO journal.
[39] P. Russell,et al. Cell cycle regulation of human WEE1. , 1995, The EMBO journal.
[40] H. Piwnica-Worms,et al. Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. , 1992, Science.
[41] P. Nurse. Universal control mechanism regulating onset of M-phase , 1990, Nature.
[42] J. Guan. Cell biology. Integrins, rafts, Rac, and Rho. , 2004, Science.
[43] M. A. del Pozo. Integrin signaling and lipid rafts. , 2004, Cell cycle.