Pearls & Oy-sters: The effects of renal replacement therapy on cerebral autoregulation

PEARLS  Hemodialysis (HD) has been associated with increases in intracranial pressure (ICP). Osmotic shifts occurring during HD are thought to be associated with the development of this phenomenon.  In comatose patients with acute brain injury, an elevation of ICP during HD may be associated with worse cerebral autoregulation. Continuous veno-venous hemofiltration (CVVH) may be a safer alternative in these patients. OYSTER  HD may increase ICP; therefore, caution should be exercised when HD is needed in patients with acute brain injury. CASE REPORT A 59-year-old man with hyperten

[1]  S. Conrad,et al.  Continuous Renal Replacement Therapies: A Brief Primer for the Neurointensivist , 2010, Neurocritical care.

[2]  P. Mahieu,et al.  Intracranial pressure changes in patients with head trauma during haemodialysis , 2005, Intensive Care Medicine.

[3]  Jeffrey J. Fletcher,et al.  Continuous renal replacement therapy for refractory intracranial hypertension? , 2010, The Journal of trauma.

[4]  J. Desimone,et al.  Dialysis disequilibrium syndrome (DDS) in the rat: role of the "reverse urea effect". , 1992, Kidney international.

[5]  C. Hollenbeak,et al.  A systematic review of continuous renal replacement therapy and intermittent haemodialysis in management of patients with acute renal failure , 2008, Nephrology.

[6]  R. Dechert,et al.  Elevated intracranial pressure associated with hypermetabolism in isolated head trauma , 2005, Acta Neurochirurgica.

[7]  A. Davenport Renal replacement therapy for the patient with acute traumatic brain injury and severe acute kidney injury. , 2007, Contributions to nephrology.

[8]  S. Silver,et al.  Brain swelling after dialysis: old urea or new osmoles? , 1996, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[9]  A. Davenport,et al.  Early changes in intracranial pressure during haemofiltration treatment in patients with grade 4 hepatic encephalopathy and acute oliguric renal failure. , 1990, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[10]  J. Pickard,et al.  Continuous assessment of the cerebral vasomotor reactivity in head injury. , 1997, Neurosurgery.