Dilated Cardiomyopathy: Phosphorus 31 MR Spectroscopy at 7 T

Cardiac phosphorus spectroscopy is demonstrated to be feasible in patients at 7 T, giving higher signal-to-noise ratios and more precise quantification of the phosphocreatine to adenosine triphosphate concentration ratio than at 3 T in a group of 25 patients with dilated cardiomyopathy.

[1]  M. Robson,et al.  31P cardiac magnetic resonance spectroscopy during leg exercise at 3 Tesla , 2009, The International Journal of Cardiovascular Imaging.

[2]  Paul A Bottomley,et al.  ATP flux through creatine kinase in the normal, stressed, and failing human heart. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[3]  J. Francis,et al.  Myocardial Steatosis and Left Ventricular Contractile Dysfunction in Patients With Severe Aortic Stenosis , 2013, Circulation. Cardiovascular imaging.

[4]  M. Robson,et al.  Receive array magnetic resonance spectroscopy: Whitened singular value decomposition (WSVD) gives optimal Bayesian solution , 2010, Magnetic resonance in medicine.

[5]  D. Beard,et al.  Human Cardiac 31P-MR Spectroscopy at 3 Tesla Cannot Detect Failing Myocardial Energy Homeostasis during Exercise , 2017, Front. Physiol..

[6]  G. Bodenhausen,et al.  Principles of nuclear magnetic resonance in one and two dimensions , 1987 .

[7]  S. Neubauer,et al.  Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy. , 1997, Circulation.

[8]  Y. Hama Prone positioning causes the heart to be displaced anteriorly within the thorax: implications for breast cancer treatment. , 2008, International journal of radiation oncology, biology, physics.

[9]  C J Hardy,et al.  An NMR Phased Array for Human Cardiac 31P Spectroscopy , 1992, Magnetic resonance in medicine.

[10]  Lucian A B Purvis,et al.  Using a whole-body 31P birdcage transmit coil and 16-element receive array for human cardiac metabolic imaging at 7T , 2017, PloS one.

[11]  V. Roger Epidemiology of Heart Failure , 2013, Circulation research.

[12]  S. Neubauer,et al.  31P Magnetic Resonance Spectroscopy in Dilated Cardiomyopathy and Coronary Artery Disease: Altered Cardiac High‐Energy Phosphate Metabolism in Heart Failure , 1992, Circulation.

[13]  C. Hardy,et al.  Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy. , 1991, American heart journal.

[14]  Thoralf Niendorf,et al.  Acoustic cardiac triggering: a practical solution for synchronization and gating of cardiovascular magnetic resonance at 7 Tesla , 2010, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[15]  S. Neubauer,et al.  Contributions of 31P-magnetic resonance spectroscopy to the understanding of dilated heart muscle disease. , 1995, European heart journal.

[16]  M. Francone Role of Cardiac Magnetic Resonance in the Evaluation of Dilated Cardiomyopathy: Diagnostic Contribution and Prognostic Significance , 2014, ISRN radiology.

[17]  Stefan Neubauer,et al.  Human cardiac 31P magnetic resonance spectroscopy at 7 tesla , 2013, Magnetic resonance in medicine.

[18]  Paul A. Bottomley,et al.  NMR Spectroscopy of the Human Heart , 2009 .

[19]  Vanhamme,et al.  Improved method for accurate and efficient quantification of MRS data with use of prior knowledge , 1997, Journal of magnetic resonance.

[20]  M. Pasque,et al.  Magnetic resonance imaging detects significant sex differences in human myocardial strain , 2011, Biomedical engineering online.

[21]  J. Cohn,et al.  Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: reliability and validity during a randomized, double-blind, placebo-controlled trial of pimobendan. Pimobendan Multicenter Research Group. , 1992, American heart journal.

[22]  Kieran Clarke,et al.  A comparison of cardiac 31P MRS at 1.5 and 3 T , 2008, NMR in biomedicine.

[23]  R. R. Ernst,et al.  Application of Fourier Transform Spectroscopy to Magnetic Resonance , 1966 .

[24]  S. Semple,et al.  Human cardiac 31P magnetic resonance spectroscopy at 3T with a receive array: is single-loop or dual-loop RF transmission superior? , 2015, Journal of Cardiovascular Magnetic Resonance.

[25]  S. Neubauer,et al.  31P-nuclear magnetic resonance spectroscopy of blood: a species comparison. , 2000, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[26]  M. Robson,et al.  Reproducibility of 31P cardiac magnetic resonance spectroscopy at 3 T , 2009, NMR in biomedicine.

[27]  S. Petersen,et al.  Gender-specific differences in left ventricular remodelling in obesity: insights from cardiovascular magnetic resonance imaging. , 2013, European heart journal.

[28]  D van Ormondt,et al.  Cramér–Rao bounds: an evaluation tool for quantitation , 2001, NMR in biomedicine.

[29]  E. M. Pedersen,et al.  Single breath-hold slice-following CSPAMM myocardial tagging , 1999, Magnetic Resonance Materials in Physics, Biology and Medicine.