Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling

[1]  G. Hoxhaj,et al.  The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism , 2019, Nature Reviews Cancer.

[2]  Andrew P Feinberg,et al.  The Key Role of Epigenetics in Human Disease Prevention and Mitigation. , 2018, The New England journal of medicine.

[3]  D. Chen,et al.  IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades , 2018, Scientific Reports.

[4]  Sheng-Jie Yu,et al.  Esophageal cancer: Risk factors, genetic association, and treatment. , 2016, Asian journal of surgery.

[5]  J. Herman,et al.  Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling , 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[6]  M. Guo,et al.  The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma , 2016, Clinical Epigenetics.

[7]  N. Hu,et al.  Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer. , 2016, Cancer research.

[8]  M. Kashyap.  Role of insulin-like growth factor-binding proteins in the pathophysiology and tumorigenesis of gastroesophageal cancers , 2015, Tumor Biology.

[9]  Nobhojit Roy,et al.  The Global Burden of Cancer 2013. , 2015, JAMA oncology.

[10]  H. Atreya,et al.  Insulin-Like Growth Factor System in Cancer: Novel Targeted Therapies , 2015, BioMed research international.

[11]  J. Herman,et al.  Epigenetic changes and functional study of HOXA11 in human gastric cancer. , 2015, Epigenomics.

[12]  Jing Wang,et al.  Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance , 2014, Genes & diseases.

[13]  J. Blenis,et al.  The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the eIF4B-Dependent Control of c-Myc Translation , 2014, Current Biology.

[14]  R. Baxter,et al.  IGF binding proteins in cancer: mechanistic and clinical insights , 2014, Nature Reviews Cancer.

[15]  Qiang Feng,et al.  Identification of genomic alterations in oesophageal squamous cell cancer , 2014, Nature.

[16]  J. Herman,et al.  Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer , 2013, Epigenetics.

[17]  J. Herman,et al.  Epigenetic silencing of CXCL14 induced colorectal cancer migration and invasion. , 2013, Discovery medicine.

[18]  J. Herman,et al.  Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer. , 2012, The Journal of molecular diagnostics : JMD.

[19]  Yuchen Jiao,et al.  Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. , 2012, Cancer discovery.

[20]  G. Jin,et al.  Epidemiologic differences in esophageal cancer between Asian and Western populations , 2012, Chinese journal of cancer.

[21]  Howard Slomko,et al.  Minireview: Epigenetics of obesity and diabetes in humans. , 2012, Endocrinology.

[22]  Andrew E. Teschendorff,et al.  Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip. , 2010, Methods.

[23]  S. Blumenthal.  From Insulin and Insulin-Like Activity to the Insulin Superfamily of Growth-Promoting Peptides: A 20th-Century Odyssey , 2010, Perspectives in biology and medicine.

[24]  E. Montgomery,et al.  Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers , 2009, Cancer biology & therapy.

[25]  L. Nicholson,et al.  Epigenetic Inactivation Implies Independent Functions for Insulin-like Growth Factor Binding Protein (IGFBP)-Related Protein 1 and the Related IGFBPL1 in Inhibiting Breast Cancer Phenotypes , 2007, Clinical Cancer Research.

[26]  D. Carbone,et al.  Insulin-like growth factor-I receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma. , 2006, Carcinogenesis.

[27]  Xiaomei Ma,et al.  Global Burden of Cancer , 2006, The Yale journal of biology and medicine.

[28]  C. Wild,et al.  IGFBP-3 and IGFBP-10 (CYR61) up-regulation during the development of Barrett's oesophagus and associated oesophageal adenocarcinoma: potential biomarkers of disease risk , 2006, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[29]  W. Funk,et al.  Identification of a novel insulin-like growth factor binding protein gene homologue with tumor suppressor like properties. , 2005, Biochemical and biophysical research communications.

[30]  W. El-Deiry,et al.  Epidermal Growth Factor Receptor Regulates Aberrant Expression of Insulin-Like Growth Factor-Binding Protein 3 , 2004, Cancer Research.

[31]  Tsung-Teh Wu,et al.  Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[32]  A. Feinberg,et al.  Loss of IGF2 Imprinting: A Potential Marker of Colorectal Cancer Risk , 2003, Science.

[33]  Shan-Chun Chen,et al.  Autocrine Stimulation by Insulin-Like Growth Factor I Is Involved in the Growth, Tumorigenicity and Chemoresistance of Human Esophageal Carcinoma Cells , 2002, Journal of Biomedical Science.

[34]  S. Law,et al.  Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: overexpression of oncogene MET correlates with tumor differentiation in ESCC. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[35]  M. West,et al.  Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway , 1998, Oncogene.

[36]  J. Herman,et al.  Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[37]  R. Rosenfeld,et al.  Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition. , 1993, The Journal of biological chemistry.

[38]  Shan-Chun Chen,et al.  Overexpression of epidermal growth factor and insulin-like growth factor-I receptors and autocrine stimulation in human esophageal carcinoma cells. , 1991, Cancer research.

[39]  J. Schwander,et al.  Insulin-Like Growth Factor-Binding Protein , 1989, Definitions.

[40]  J. Herman,et al.  DACT2 is frequently methylated in human gastric cancer and methylation of DACT2 activated Wnt signaling. , 2014, American journal of cancer research.

[41]  J. Luketich,et al.  Oesophageal carcinoma , 2013, The Lancet.

[42]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[43]  Shan-Chun Chen,et al.  Autocrine stimulation by insulin-like growth factor I is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells. , 2002, Journal of biomedical science.