Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins.

[1]  William McGinnis,et al.  Homeobox genes and axial patterning , 1992, Cell.

[2]  David Baltimore,et al.  A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all , 1990, Cell.

[3]  M. Cleary,et al.  PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1 , 1991, Molecular and cellular biology.

[4]  M. Cleary.  Transcription factors in human leukaemias. , 1992, Cancer surveys.

[5]  E. Wieschaus,et al.  Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins. , 1994, The EMBO journal.

[6]  D. Duboule,et al.  Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body. , 1991, The EMBO journal.

[7]  A. Garcı́a-Bellido.  Homoeotic and atavic mutations in insects , 1977 .

[8]  I. Rambaldi,et al.  Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif , 1995, Molecular and cellular biology.

[9]  B. Sun,et al.  The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. , 1994, The EMBO journal.

[10]  C. Murre,et al.  Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2 , 1995, Mechanisms of Development.

[11]  P. O’Farrell,et al.  A universal target sequence is bound in vitro by diverse homeodomains , 1993, Mechanisms of Development.

[12]  E. Wieschaus,et al.  Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. , 1990, Genes & development.

[13]  R. Mann.  The specificity of homeotic gene function , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.

[14]  L. Brocchieri,et al.  Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus , 1996, Molecular and cellular biology.

[15]  Michael L. Cleary,et al.  Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor , 1990, Cell.

[16]  W. Gehring,et al.  Redesigning the body plan of Drosophilaby ectopic expression of the homoeotic gene Antennapedia , 1987, Nature.

[17]  C. Wolberger,et al.  Crystal Structure of the MATa1/MATα2 Homeodomain Heterodimer Bound to DNA , 1995, Science.

[18]  R. Mann,et al.  Functional dissection of ultrabithorax proteins in D. melanogaster , 1990, Cell.

[19]  Q. Lu,et al.  Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation , 1994, Molecular and cellular biology.

[20]  Kurt Wüthrich,et al.  Homeodomain-DNA recognition , 1994, Cell.

[21]  Juan Botas,et al.  The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein , 1994, Cell.

[22]  M. Scott.  A rational nomenclature for vertebrate homeobox (HOX) genes. , 1993, Nucleic acids research.

[23]  E. Lewis.  A gene complex controlling segmentation in Drosophila , 1978, Nature.

[24]  M. Levine,et al.  Divergent homeo box proteins recognize similar DNA sequences in Drosophila , 1988, Nature.

[25]  P. O’Farrell,et al.  The sequence specificity of homeodomain-DNA interaction , 1988, Cell.

[26]  G. Ruvkun,et al.  New motif in PBX genes , 1992, Nature Genetics.

[27]  P. Beachy,et al.  Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm. , 1995, The EMBO journal.

[28]  D. Duboule.  Guidebook to the homeobox genes , 1994 .

[29]  Q. Lu,et al.  Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex , 1996, Molecular and cellular biology.

[30]  A. Laughon,et al.  DNA binding specificity of homeodomains. , 1991, Biochemistry.

[31]  J. Botas.  Control of morphogenesis and differentiation by HOM/Hox genes. , 1993, Current opinion in cell biology.

[32]  M. Cleary,et al.  Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. , 1995, Genes & development.

[33]  Alexander D. Johnson,et al.  Interaction between two homeodomain proteins is specified by a short C-terminal tail , 1994, Nature.

[34]  S. Ekker,et al.  Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. , 1991, The EMBO journal.

[35]  Q. Lu,et al.  Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes , 1995, Molecular and cellular biology.

[36]  Alexander D. Johnson,et al.  Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. , 1994, The EMBO journal.

[37]  A. Bang,et al.  Dpbx, a new homeobox gene closely related to the human proto-oncogene pbxl molecular structure and developmental expression , 1993, Mechanisms of Development.

[38]  G. Struhl,et al.  A homoeotic mutation transforming leg to antenna in Drosophila , 1981, Nature.

[39]  C. Murre,et al.  extradenticle Raises the DNA binding specificity of homeotic selector gene products , 1994, Cell.

[40]  J. Lis,et al.  Protein traffic on the heat shock promoter: Parking, stalling, and trucking along , 1993, Cell.

[41]  I. Rambaldi,et al.  A proline-rich transcriptional activation domain in murine HOXD-4 (HOX-4.2). , 1994, Nucleic acids research.

[42]  P. Knoepfler,et al.  The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1 , 1995, Molecular and cellular biology.

[43]  Richard S. Mann,et al.  Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx , 1995, Cell.