Role of clinical microbiology laboratories in the management and control of infectious diseases and the delivery of health care.

Modern medicine has led to dramatic changes in infectious diseases practice. Vaccination and antibiotic therapy have benefited millions of persons. However, constrained resources now threaten our ability to adequately manage threats of infectious diseases by placing clinical microbiology services and expertise distant from the patient and their infectious diseases physician. Continuing in such a direction threatens quality of laboratory results, timeliness of diagnosis, appropriateness of treatment, effective communication, reduction of health care-associated infections, advances in infectious diseases practice, and training of future practitioners. Microbiology laboratories are the first lines of defense for detection of new antibiotic resistance, outbreaks of foodborne infection, and a possible bioterrorism event. Maintaining high-quality clinical microbiology laboratories on the site of the institution that they serve is the current best approach for managing today's problems of emerging infectious diseases and antimicrobial agent resistance by providing good patient care outcomes that actually save money.

[1]  R. Thomson,,et al.  Controversies Affecting the Future Practice of Clinical Microbiology , 1999, Journal of Clinical Microbiology.

[2]  L. Peterson,et al.  Medical and economic benefit of a comprehensive infection control program that includes routine determination of microbial clonality. , 1999, American journal of clinical pathology.

[3]  J. A. Wilson,et al.  The efficacy of three common hospital liquid germicides to inactivate Cryptosporidium parvum oocysts. , 1999, The Journal of hospital infection.

[4]  E. Baron,et al.  Quality perceptions of microbiology services. A survey of infectious diseases specialists. , 1996, American Journal of Clinical Pathology.

[5]  S. Solomon,et al.  Requirements for Infrastructure and Essential Activities of Infection Control and Epidemiology in Hospitals: A Consensus Panel Report , 1998, Infection Control & Hospital Epidemiology.

[6]  J. Hughes Study on the efficacy of nosocomial infection control (SENIC Project): results and implications for the future. , 1988, Chemotherapy.

[7]  M. Pfaller,et al.  The clinical microbiology laboratory and infection control: emerging pathogens, antimicrobial resistance, and new technology. , 1997, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[8]  M. Żywicki Monitoring hospital-acquired infections to promote patient safety--United States, 1990-1999. , 2000, MMWR. Morbidity and mortality weekly report.

[9]  Laboratory capacity to detect antimicrobial resistance, 1998. , 2000, MMWR. Morbidity and mortality weekly report.

[10]  F. Tenover,et al.  Surveillance for the emergence and dissemination of antimicrobial resistance in bacteria. , 1997, Infectious disease clinics of North America.

[11]  L. McCaig,et al.  Food-related illness and death in the United States. , 1999, Emerging infectious diseases.

[12]  M. Lunz,et al.  The impact of the quality of laboratory staff on the accuracy of laboratory results. , 1987, JAMA.

[13]  J. Steckelberg,et al.  Clinical aspects of antimicrobial resistance. , 2000, Mayo Clinic proceedings.

[14]  R. Spencer,et al.  Laboratory role in the management of hospital acquired infections. , 1999, The Journal of hospital infection.

[15]  E. Baron,et al.  Bailey and Scott's Diagnostic microbiology , 1982 .

[16]  E. Baron,et al.  Infectious disease physicians rate microbiology services and practices , 1996, Journal of clinical microbiology.

[17]  B. Unger,et al.  Effects of restructuring on the performance of microbiology laboratories in Alberta. , 2009, Archives of pathology & laboratory medicine.

[18]  Jonathan Y. Richmond,et al.  Biosafety in microbiological and biomedical laboratories , 1999 .

[19]  S M Teutsch,et al.  Trends in infectious diseases mortality in the United States. , 1996, JAMA.

[20]  Quality Interagency Coordination Task Force Doing What Counts for Patient Safety , 2000 .

[21]  L. Peterson,et al.  New technology for detecting multidrug-resistant pathogens in the clinical microbiology laboratory. , 2001, Emerging infectious diseases.