Depression and Renal Pathology: Literature Review and Perspectives for Intervention

Depression in patients affected by renal disease is a relevant problem because it is related to a increase of death and hospitalization rate and to a reduction of compliance. The pharmacological treatments result to be the best therapy of choice, however there is a greater difficulty in treating depressive symptoms that occur in comorbidity with renal disease, than when depression is the only disease. Various studies show that this problem can be addressed through an integrated pharmacological and psychotherapeutic intervention, which presents an additive effect in the treatment of this pathology. In relation to renal disease various studies suggest the effectiveness of psychotherapeutic intervention in the treatment of depressive symptoms, but more research is needed to compare the effectiveness of the different psychotherapeutic approaches.

[1]  Raymond Vanholder,et al.  Antidepressants for depression in stage 3-5 chronic kidney disease: a systematic review of pharmacokinetics, efficacy and safety with recommendations by European Renal Best Practice (ERBP). , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[2]  David W. Johnson,et al.  Depression and sexual dysfunction in chronic kidney disease: a narrative review of the evidence in areas of significant unmet need. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[3]  M. Knapp,et al.  Cost-effectiveness comparisons between antidepressant treatments in depression: evidence from database analyses and prospective studies. , 2012, Journal of affective disorders.

[4]  D. Cukor,et al.  Depression and nonadherence predict mortality in hemodialysis treated end‐stage renal disease patients , 2012, Hemodialysis international. International Symposium on Home Hemodialysis.

[5]  S. Hedayati,et al.  A practical approach to the treatment of depression in patients with chronic kidney disease and end-stage renal disease. , 2012, Kidney international.

[6]  G. Keskin,et al.  The evaluation of depression, suicidal ideation and coping strategies in haemodialysis patients with renal failure. , 2011, Journal of clinical nursing.

[7]  A. Nardi,et al.  Factors associated with risk of suicide in patients with hemodialysis. , 2011, Comprehensive psychiatry.

[8]  M. Fallon Depression in end-stage renal disease. , 2011, Journal of psychosocial nursing and mental health services.

[9]  G. Andersson,et al.  Interpersonal psychotherapy for depression: a meta-analysis. , 2011, The American journal of psychiatry.

[10]  Jerry L. Grenard,et al.  Depression and Medication Adherence in the Treatment of Chronic Diseases in the United States: A Meta-Analysis , 2011, Journal of General Internal Medicine.

[11]  G. Andersson,et al.  Psychological treatment of depression in inpatients: a systematic review and meta-analysis. , 2011, Clinical psychology review.

[12]  T. Lennie,et al.  Depressive symptoms and dietary adherence in patients with end-stage renal disease. , 2011, Journal of renal care.

[13]  R. Shapiro,et al.  Predicting medication adherence and employment status following kidney transplant: The relative utility of traditional and everyday cognitive approaches. , 2010, Neuropsychology.

[14]  A. Rush,et al.  Association between major depressive episodes in patients with chronic kidney disease and initiation of dialysis, hospitalization, or death. , 2010, JAMA.

[15]  Gerhard Andersson,et al.  Psychotherapy for chronic major depression and dysthymia: a meta-analysis. , 2010, Clinical psychology review.

[16]  P. Cuijpers,et al.  The efficacy of short-term psychodynamic psychotherapy for depression: a meta-analysis. , 2010, Clinical psychology review.

[17]  J. Markowitz,et al.  Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial. , 2009, Archives of general psychiatry.

[18]  R. Sesso,et al.  Cognitive-behavioral group therapy is an effective treatment for major depression in hemodialysis patients. , 2009, Kidney international.

[19]  P. Kimmel,et al.  Depression is an important contributor to low medication adherence in hemodialyzed patients and transplant recipients. , 2009, Kidney international.

[20]  Christopher Brown Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression. , 2009, Kidney international.

[21]  P. Kimmel,et al.  Suicide in the United States end-stage renal disease program. , 2005, Journal of the American Society of Nephrology : JASN.

[22]  P. Verhaak,et al.  Chronic disease and mental disorder. , 2005, Social science & medicine.

[23]  B. Piraino,et al.  The Effect of Depressive Symptoms on Survival in Peritoneal Dialysis Patients , 2004, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.

[24]  R. Jindal,et al.  Prospective randomized study of individual and group psychotherapy versus controls in recipients of renal transplants1 , 2004 .

[25]  A. Soykan,et al.  Suicidal behavior, satisfaction with life, and perceived social support in end-stage renal disease. , 2003, Transplantation proceedings.

[26]  P. Kimmel Depression in patients with chronic renal disease: what we know and what we need to know. , 2002, Journal of psychosomatic research.

[27]  P. Kimmel,et al.  Survival in hemodialysis patients: the role of depression. , 1993, Journal of the American Society of Nephrology : JASN.

[28]  R. Jindal,et al.  Prospective randomized study of individual and group psychotherapy versus controls in recipients of renal transplants. , 2004, Kidney international.