Autonomic neural control of cerebral hemodynamics

The present article examines the role of autonomic neural control on both dynamic pressure autoregulation and CO2 reactivity in the frequency range between 0.005 and 0.40 Hz by analyzing experimental data from healthy humans and using a nonlinear multivariate modeling approach. The data were obtained during control conditions and autonomic ganglionic blockade, induced by intravenous infusion of trimethaphan. This approach has been successfully used previously to describe cerebral hemodynamics during resting conditions and orthostatic stress.

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