Calixarene Phosphonous Acids: Synthesis and Biological Activity

Abstract The cone shaped сalix[4]arene hydroxyphosponous, ketophosphonous, methylenebisphosphonous, and hydroxymethylenebisphosphonous acids are specific inhibitors of glutathione S-transferase, ATPases of smooth muscle cells, fibrin polymerization processes GRAPHICAL ABSTRACT

[1]  V. Kalchenko,et al.  Calix(4)arene-α-hydroxyphosphonic acids. Synthesis, stereochemistry, and inhibition of glutathione S-transferase , 2012 .

[2]  P. G. Gritsenko,et al.  Calix[4]arene methylenebisphosphonic acids as inhibitors of fibrin polymerization , 2011, The FEBS journal.

[3]  V. Kalchenko,et al.  Phosphorylated Calix[4]arenes as Inhibitors of Glutathione S-Transferase , 2011 .

[4]  Â. de Fátima,et al.  Calixarenes as new platforms for drug design. , 2009, Current drug discovery technologies.

[5]  R. Rodik,et al.  Calixarenes in bio-medical researches. , 2009, Current medicinal chemistry.

[6]  V. Kalchenko,et al.  Phosphorus-Containing Calixarenes , 2009 .

[7]  V. Kalchenko.  Calixarene receptors of environmentally hazardous and biorelevant molecules and ions , 2008 .

[8]  F. Perret,et al.  Calix[n]arenes as Protein Sensors , 2007 .

[9]  J. Harrowfield,et al.  Calixarenes in the nanoworld , 2007 .

[10]  F. Perret,et al.  Biochemistry of the para-sulfonato-calix[n]arenes. , 2006, Chemical communications.

[11]  T. Schrader,et al.  Nanomolar protein sensing with embedded receptor molecules. , 2005, Journal of the American Chemical Society.

[12]  V. Kalchenko,et al.  Calix[4]arene methylenebisphosphonic acids as calf intestine alkaline phosphatase inhibitors. , 2004, Organic & biomolecular chemistry.

[13]  A. Lazar,et al.  Biopharmaceutical applications of calixarenes , 2004 .

[14]  F. Sansone,et al.  Peptido- and glycocalixarenes: playing with hydrogen bonds around hydrophobic cavities. , 2003, Accounts of chemical research.

[15]  G. Lumetta,et al.  Calixarenes for separations , 2000 .

[16]  A. Hamilton,et al.  Protein Surface Recognition by Synthetic Receptors: A Route to Novel Submicromolar Inhibitors for α-Chymotrypsin , 1999 .