EVI1 splice variants modulate functional responses in ovarian cancer cells

[1]  Guillaume Bourque,et al.  Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors , 2012, Proceedings of the National Academy of Sciences.

[2]  L. Meijer,et al.  Targeting low molecular weight cyclin E (LMW-E) in breast cancer , 2012, Breast Cancer Research and Treatment.

[3]  F. Speleman,et al.  EVI1‐mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells , 2011, British journal of haematology.

[4]  I. Rigoutsos,et al.  The Evi1, microRNA‐143, K‐Ras axis in colon cancer , 2011, FEBS letters.

[5]  K. Coombes,et al.  Proteomic Profiling Identifies Pathways Dysregulated in Non-small Cell Lung Cancer and an Inverse Association of AMPK and Adhesion Pathways with Recurrence , 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[6]  F. Prósper,et al.  Silencing of hsa-miR-124 by EVI1 in cell lines and patients with acute myeloid leukemia , 2010, Proceedings of the National Academy of Sciences.

[7]  M. Odero,et al.  EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2 , 2010, British Journal of Cancer.

[8]  M. S. Dalton,et al.  Evaluation of EVI1 and EVI1s (Delta324) as potential therapeutic targets in ovarian cancer. , 2010, Gynecologic oncology.

[9]  G. Nucifora,et al.  Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome , 2010, Proceedings of the National Academy of Sciences.

[10]  Shetal Patel,et al.  ARSENIC TRIOXIDE INDUCES A BECLIN-1 INDEPENDENT AUTOPHAGIC PATHWAY VIA MODULATION OF SNON/SKIL EXPRESSION IN OVARIAN CARCINOMA CELLS , 2010, Cell Death and Differentiation.

[11]  Derek Y. Chiang,et al.  The landscape of somatic copy-number alteration across human cancers , 2010, Nature.

[12]  Björn Olsson,et al.  Potential predictive markers of chemotherapy resistance in stage III ovarian serous carcinomas , 2009, BMC Cancer.

[13]  Cameron P Bracken,et al.  MicroRNAs as regulators of epithelial-mesenchymal transition , 2008, Cell cycle.

[14]  G. Goodall,et al.  The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition , 2008, TheScientificWorldJournal.

[15]  M. Korpal,et al.  The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2* , 2008, Journal of Biological Chemistry.

[16]  G. Goodall,et al.  The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 , 2008, Nature Cell Biology.

[17]  Sun-Mi Park,et al.  The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. , 2008, Genes & development.

[18]  I. Rimann,et al.  Regulation of anchor cell invasion and uterine cell fates by the egl-43 Evi-1 proto-oncogene in Caenorhabditis elegans. , 2007, Developmental biology.

[19]  Wen-Lin Kuo,et al.  Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer. , 2007, Cancer research.

[20]  M. Pajares,et al.  Alternative splicing: an emerging topic in molecular and clinical oncology. , 2007, The Lancet. Oncology.

[21]  A. Krainer,et al.  The gene encoding the splicing factor SF2/ASF is a proto-oncogene , 2007, Nature Structural &Molecular Biology.

[22]  R. McGilvray,et al.  Conservation and expression of a novel alternatively spliced Evi1 exon. , 2006, Gene.

[23]  G. Mills,et al.  Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells , 2006, Molecular Cancer Therapeutics.

[24]  S. Mok,et al.  Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer. , 2006, Cancer research.

[25]  T. Cooper,et al.  Minigene reporter for identification and analysis of cis elements and trans factors affecting pre-mRNA splicing. , 2006, BioTechniques.

[26]  S. Reed,et al.  Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer. , 2006, Cancer research.

[27]  J. Lawrence,et al.  Molecular anatomy of a speckle. , 2006, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

[28]  S. Spanò,et al.  Mechanisms Directing the Nuclear Localization of the CtBP Family Proteins , 2006, Molecular and Cellular Biology.

[29]  T. Cooper.  Use of minigene systems to dissect alternative splicing elements. , 2005, Methods.

[30]  Gordon B Mills,et al.  Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[31]  R. Wieser,et al.  Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5'-ends. , 2005, Gene.

[32]  J. Cheng,et al.  Molecular and Genetic Studies Imply Akt-mediated Signaling Promotes Protein Kinase CβII Alternative Splicing via Phosphorylation of Serine/Arginine-rich Splicing Factor SRp40* , 2005, Journal of Biological Chemistry.

[33]  Gerard C Blobe,et al.  Role of transforming growth factor Beta in human cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[34]  Graham Dellaire,et al.  PML nuclear bodies: dynamic sensors of DNA damage and cellular stress , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

[35]  N. Patel,et al.  Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene. , 2004, Molecular endocrinology.

[36]  Shoichiro Tsukita,et al.  Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail , 2003, Journal of Cell Science.

[37]  G. Nucifora,et al.  Interaction of EVI1 with cAMP-responsive Element-binding Protein-binding Protein (CBP) and p300/CBP-associated Factor (P/CAF) Results in Reversible Acetylation of EVI1 and in Co-localization in Nuclear Speckles* , 2001, The Journal of Biological Chemistry.

[38]  M. Kurokawa,et al.  Oncogenic mechanisms of Evi-1 protein , 2001, Cancer Chemotherapy and Pharmacology.

[39]  M. Kurokawa,et al.  The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling. , 2001, Blood.

[40]  H. Hirai.  The transcription factor Evi-1. , 1999, The international journal of biochemistry & cell biology.

[41]  P. Fisher,et al.  Role of the transcription factor AP-1 in melanoma differentiation (review). , 1998, International journal of oncology.

[42]  K. Irie,et al.  The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3 , 1998, Nature.

[43]  A. Kilbey,et al.  Evi-1 ZF1 DNA binding activity and a second distinct transcriptional repressor region are both required for optimal transformation of Rat1 fibroblasts , 1998, Oncogene.

[44]  H. de Thé,et al.  Induction of the PML protein by interferons in normal and APL cells. , 1995, Leukemia.

[45]  M. Kurokawa,et al.  Growth inhibition of leukaemic cells carrying the t(3;21) by the AML1/EVI‐1 ‐specific antisense oligonucleotide , 1995, British journal of haematology.

[46]  J. Ihle,et al.  DNA rearrangements proximal to the EVI1 locus associated with the 3q21q26 syndrome. , 1994, Blood.

[47]  J. Ihle,et al.  Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[48]  J. Ihle,et al.  Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor , 1992, Molecular and cellular biology.

[49]  J. Ihle,et al.  Unique expression of the human Evi-1 gene in an endometrial carcinoma cell line: sequence of cDNAs and structure of alternatively spliced transcripts. , 1990, Oncogene.

[50]  J. Ihle,et al.  Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene , 1990, Molecular and cellular biology.