Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD
暂无分享,去创建一个
F. Sciurba | S. Shapiro | M. Rojas | T. Nyunoya | Yingze Zhang | R. Faner | G. Noell | Kong Chen | M. Snyder | R. Lafyatis | J. McDyer | J. Sembrat | H. T. Trejo Bittar | Xiu-ying Li | C. Zou | P. Sundd | D. Chandra | R. Vats | T. Tabib | A. Gregory | T. Kaminski | T. Kamiński | S. Shapiro
[1] G. Washko,et al. Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis , 2020, Science Advances.
[2] J. Hogg,et al. Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease. , 2019, The New England journal of medicine.
[3] D. Sahoo,et al. miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells. , 2019, Cancer research.
[4] P. Benos,et al. Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis , 2019, European Respiratory Journal.
[5] Eleni G. Christodoulou,et al. Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins , 2019, Circulation.
[6] A. Shilatifard,et al. Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis , 2019, American journal of respiratory and critical care medicine.
[7] M. Rojas,et al. Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung disease , 2019, Annals of the Rheumatic Diseases.
[8] E. Silverman,et al. RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD , 2019, Respiratory Research.
[9] E. Silverman,et al. Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis , 2019, Respiratory Research.
[10] Benjamin B. Sun,et al. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. , 2018, Nature Genetics.
[11] Alteration of primary cilia in COPD , 2018, European Respiratory Journal.
[12] Y. Taniyama,et al. IGF Binding Protein-5 Induces Cell Senescence , 2018, Front. Endocrinol..
[13] Wei Chen,et al. SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin. , 2017, The Journal of investigative dermatology.
[14] M. Obeidat,et al. Integrative Genomics of Emphysema‐Associated Genes Reveals Potential Disease Biomarkers , 2017, American journal of respiratory cell and molecular biology.
[15] J. Cooper,et al. The cellular and molecular determinants of emphysematous destruction in COPD , 2017, Scientific Reports.
[16] D. DeMeo,et al. Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue , 2017, Scientific Reports.
[17] B. Stripp,et al. Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. , 2016, JCI insight.
[18] P. Barnes,et al. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. , 2016, The Journal of allergy and clinical immunology.
[19] R. Rodríguez-Roisín,et al. Network Analysis of Lung Transcriptomics Reveals a Distinct B-Cell Signature in Emphysema. , 2016, American journal of respiratory and critical care medicine.
[20] M. Ares,et al. Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression , 2016, Nature Communications.
[21] Yonghao Yu,et al. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling , 2016, Nature Cell Biology.
[22] Evan Z. Macosko,et al. Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets , 2015, Cell.
[23] I. Rahman,et al. Impaired mitophagy leads to cigarette smoke stress‐induced cellular senescence: implications for chronic obstructive pulmonary disease , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[24] B. Celli,et al. Protective role for club cell secretory protein-16 (CC16) in the development of COPD , 2015, European Respiratory Journal.
[25] A. Regev,et al. Spatial reconstruction of single-cell gene expression , 2015, Nature Biotechnology.
[26] Joshua D. Campbell,et al. Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction , 2014, Thorax.
[27] R. Baxter,et al. IGF binding proteins in cancer: mechanistic and clinical insights , 2014, Nature Reviews Cancer.
[28] Donavan T. Cheng,et al. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. , 2013, American journal of respiratory and critical care medicine.
[29] T. Self,et al. The clinical and economic burden of chronic obstructive pulmonary disease in the USA , 2013, ClinicoEconomics and outcomes research : CEOR.
[30] I. Rahman,et al. Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. , 2013, Antioxidants & redox signaling.
[31] V. Kim,et al. Chronic bronchitis and chronic obstructive pulmonary disease. , 2013, American journal of respiratory and critical care medicine.
[32] Avrum Spira,et al. A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK , 2012, Genome Medicine.
[33] D. Mannino,et al. Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease , 2012, Thorax.
[34] Guangchuang Yu,et al. clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.
[35] Matko Bosnjak,et al. REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms , 2011, PloS one.
[36] Meilan K. Han,et al. Update in chronic obstructive pulmonary disease in 2010. , 2011, American journal of respiratory and critical care medicine.
[37] P. Barnes,et al. COPD as a disease of accelerated lung aging(a). , 2009, Revista portuguesa de pneumologia.
[38] Shyam Biswal,et al. Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression. , 2009, American journal of physiology. Lung cellular and molecular physiology.
[39] Kazuhiro Ito,et al. Translating Basic Research Into Clinical Practice COPD as a Disease of Accelerated Lung Aging * , 2009 .
[40] MScPH MSc David W. Brown DSc. Smoking Prevalence among US Veterans , 2009, Journal of General Internal Medicine.
[41] J. Beattie,et al. Epithelial injury induces an innate repair mechanism linked to cellular senescence and fibrosis involving IGF-binding protein-5. , 2008, The Journal of endocrinology.
[42] Hongmin Sun,et al. The interaction between pathogens and the host coagulation system. , 2006, Physiology.
[43] Robert Wise,et al. Predictors of mortality in patients with emphysema and severe airflow obstruction. , 2006, American journal of respiratory and critical care medicine.
[44] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[45] Irina Petrache,et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. , 2004, The Journal of clinical investigation.
[46] B. Celli,et al. Gene expression profiling of human lung tissue from smokers with severe emphysema. , 2004, American journal of respiratory cell and molecular biology.
[47] J. Hogg,et al. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease , 2004, The Lancet.
[48] P. Paré,et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. , 2004, The New England journal of medicine.
[49] S Miyano,et al. Open source clustering software. , 2004, Bioinformatics.
[50] A. Boyle,et al. Update on chronic obstructive pulmonary disease. , 2004, Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses.
[51] R. Pauwels,et al. Chronic obstructive pulmonary disease: molecular and cellularmechanisms , 2003, European Respiratory Journal.
[52] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..
[53] R. Stockley. Neutrophils and protease/antiprotease imbalance. , 1999, American journal of respiratory and critical care medicine.
[54] L. Fabbri,et al. CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. , 1998, American journal of respiratory and critical care medicine.
[55] K. Artzt,et al. STAR, a gene family involved in signal transduction and activation of RNA. , 1997, Trends in genetics : TIG.
[56] M. Justice,et al. The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins , 1996, Nature Genetics.
[57] B. M. Lewis,et al. THE NATURAL HISTORY OF EMPHYSEMA. , 1964, Geriatrics.