Plk1 Controls the Nek2A-PP1γ Antagonism in Centrosome Disjunction

[1]  A. Fry,et al.  Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction , 2010, Nature Cell Biology.

[2]  U. Surana,et al.  Regulation of centrosome separation in yeast and vertebrates: common threads. , 2009, Trends in cell biology.

[3]  Florian Gnad,et al.  Large-scale Proteomics Analysis of the Human Kinome , 2009, Molecular & Cellular Proteomics.

[4]  Stephen S. Taylor,et al.  Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery , 2008, Nature.

[5]  M. Mann,et al.  Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. , 2008, Molecular cell.

[6]  S. Elledge,et al.  A quantitative atlas of mitotic phosphorylation , 2008, Proceedings of the National Academy of Sciences.

[7]  J. Yates,et al.  Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry , 2008, Science.

[8]  Chao Zhang,et al.  Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells , 2007, Proceedings of the National Academy of Sciences.

[9]  J. Peters,et al.  The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1 , 2007, Current Biology.

[10]  J. Mi,et al.  Protein Phosphatase-1α Regulates Centrosome Splitting through Nek2 , 2007 .

[11]  J. Mi,et al.  Protein phosphatase-1alpha regulates centrosome splitting through Nek2. , 2007, Cancer research.

[12]  H. Saya,et al.  NDEL1 Phosphorylation by Aurora-A Kinase Is Essential for Centrosomal Maturation, Separation, and TACC3 Recruitment , 2006, Molecular and Cellular Biology.

[13]  Uttam Surana,et al.  Cdk1 regulates centrosome separation by restraining proteolysis of microtubule‐associated proteins , 2006, The EMBO journal.

[14]  J. R. Daum,et al.  The reversibility of mitotic exit in vertebrate cells , 2006, Nature.

[15]  Tiansen Li,et al.  Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells. , 2005, Molecular biology of the cell.

[16]  Christopher J. Wilkinson,et al.  Rootletin forms centriole-associated filaments and functions in centrosome cohesion , 2005, The Journal of cell biology.

[17]  M. Garrett,et al.  Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors. , 2005, Current opinion in pharmacology.

[18]  David Bebbington,et al.  VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo , 2004, Nature Medicine.

[19]  Jerry H. Wang,et al.  Regulation of Mammalian STE20-like Kinase 2 (MST2) by Protein Phosphorylation/Dephosphorylation and Proteolysis* , 2003, The Journal of Biological Chemistry.

[20]  T. Mayor,et al.  The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. , 2002, Journal of cell science.

[21]  D. Berdnik,et al.  Drosophila Aurora-A Is Required for Centrosome Maturation and Actin-Dependent Asymmetric Protein Localization during Mitosis , 2002, Current Biology.

[22]  Anthony A. Hyman,et al.  Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans , 2001, The Journal of cell biology.

[23]  T. Mayor,et al.  The Centrosomal Protein C-Nap1 Is Required for Cell Cycle–Regulated Centrosome Cohesion , 2000, The Journal of cell biology.

[24]  P. Cohen,et al.  NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1. , 2000, The Biochemical journal.

[25]  P. Meraldi,et al.  C-Nap1, a Novel Centrosomal Coiled-Coil Protein and Candidate Substrate of the Cell Cycle–regulated Protein Kinase Nek2 , 1998, The Journal of cell biology.

[26]  H. Lane,et al.  Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes , 1996, The Journal of cell biology.

[27]  T. Mitchison,et al.  Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[28]  Timothy J. Mitchison,et al.  Mitotic spindle organization by a plus-end-directed microtubule motor , 1992, Nature.

[29]  P. Meluh,et al.  Kinesin-related proteins required for assembly of the mitotic spindle , 1992, The Journal of cell biology.