Retinal artery occlusion.

A 54-year-old man presented with an acute painless loss of vision. He had a three-month history of malaise, weight loss, and episodic sweating. Physical examination showed a thin, febrile man with a petechial rash over the lower legs. Cardiac auscultation revealed an apical thrill and pansystolic murmur. Dental hygiene was poor. The diagnosis, mechanisms and treatment of retinal artery occlusion associated with bacterial endocarditis are reviewed.

[1]  I. Ziment Nervous system complications in bacterial endocarditis. , 1969, The American journal of medicine.

[2]  A. Patz Oxygen inhalation in retinal arterial occlusion; a preliminary report. , 1955, American journal of ophthalmology-glaucoma.

[3]  B. Reisberg,et al.  Infective endocarditis in the narcotic addict. , 1979, Progress in cardiovascular diseases.

[4]  Noble O. Fowler Diagnosis of Heart Disease , 1991, Springer New York.

[5]  J. Hirschmann,et al.  Transient bacteremia and endocarditis prophylaxis. A review. , 1977, Medicine.

[6]  M. Terpenning,et al.  Infective endocarditis: clinical features in young and elderly patients. , 1987, The American journal of medicine.

[7]  K. Matsushita,et al.  Cerebral Infarction Associated With Protein C Deficiency , 1992, Stroke.

[8]  M. Samama,et al.  The role of abnormalities in the anticoagulant and fibrinolytic systems in retinal vascular occlusions. , 1993, Survey of ophthalmology.

[9]  A. Bisno,et al.  Underlying cardiac lesions in adults with infective endocarditis. The changing spectrum. , 1987, The American journal of medicine.

[10]  H. Shammas Endogenous E. coli endophthalmitis. , 1977, Survey of ophthalmology.

[11]  D. Sackett,et al.  Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. , 1991, The New England journal of medicine.

[12]  D. Kaye Changing pattern of infective endocarditis. , 1985, The American journal of medicine.

[13]  E. Graham The investigation of patients with retinal vascular occlusion , 1990, Eye.

[14]  C. K. Mcallister,et al.  The utility of Osler's nodes in the diagnosis of infective endocarditis. , 1987, Chest.

[15]  W. Green,et al.  White centered hemorrhages: their significance. , 1980, Ophthalmology.

[16]  R. E. Kalina,et al.  Retinal lesions following long bone fractures. , 1985, Ophthalmology.

[17]  N. Hausmann,et al.  Effect of high dose steroid bolus on occlusion of ocular central artery: angiographic study. , 1991, BMJ.

[18]  I. Kjellmer Mechanisms of perinatal brain damage. , 1991, Annals of medicine.

[19]  R. K. Lansche Central retinal artery occlusion. , 1965, American journal of ophthalmology.

[20]  J. Donald M. Gass Stereoscopic atlas of macular diseases , 1977 .

[21]  A. Irvine,et al.  Retinal emboli in patients with mitral valve prolapse. , 1980, American journal of ophthalmology.

[22]  M. Marmor,et al.  Dextromethorphan protects retina against ischemic injury in vivo. , 1989, Archives of ophthalmology.

[23]  L. Kline,et al.  Visual disturbances of migraine. , 1989, Survey of ophthalmology.

[24]  James B. Wyngaarden Cecil Textbook of Medicine , 1980 .

[25]  E. Gragoudas,et al.  Talc emboli and macular ischemia in intravenous drug abuse. , 1979, Archives of ophthalmology.

[26]  C. R. Kollarits,et al.  Retinal strokes. I. Incidence of carotid atheromata. , 1972, JAMA.

[27]  G. Brown,et al.  Sudden occlusion of the retinal and posterior choroidal circulations in a youth. , 1979, American journal of ophthalmology.

[28]  G. Woods,et al.  Aspergillus endocarditis in patients without prior cardiovascular surgery: report of a case in a liver transplant recipient and review. , 1989, Reviews of infectious diseases.

[29]  R. Paoletti,et al.  Thrombosis and urokinase , 1977 .

[30]  J. Augsburger,et al.  Visual prognosis following treatment of acute central retinal artery obstruction. , 1980, The British journal of ophthalmology.

[31]  W. Green,et al.  A clinicopathological case report of retinopathy of pancreatitis. , 1982, The British journal of ophthalmology.

[32]  S. Rehncrona,et al.  Brain Lactic Acidosis and Ischemic Cell Damage: 1. Biochemistry and Neurophysiology , 1981, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  B. Katz Migrainous central retinal artery occlusion. , 1986, Journal of clinical neuro-ophthalmology.

[34]  James S. M. Tan,et al.  Biopsies of the Janeway Lesion of Infective Endocarditis , 1979, Journal of cutaneous pathology.

[35]  G. Sanborn,et al.  The idling retina: reversible visual loss in central retinal artery obstruction. , 1987, Annals of ophthalmology.

[36]  D. Cogan,et al.  Vascular occlusions in the eye from cardiac myxomas. , 1975, American journal of ophthalmology.

[37]  H. Henkes Electroretinography in circulatory disturbances of the retina. I. Electroretinogram in cases of occlusion of central retinal vein or of one of its branches. , 1953, A.M.A. archives of ophthalmology.

[38]  W. Wilson,et al.  Management of complications of infective endocarditis. , 1982, Mayo Clinic proceedings.

[39]  M. Harrison,et al.  Rate of cerebral embolic events in relation to antibiotic and anticoagulant therapy in patients with bacterial endocarditis. , 1990, European neurology.

[40]  D. Levine,et al.  Bacteremia in narcotic addicts at the Detroit Medical Center. II. Infectious endocarditis: a prospective comparative study. , 1986, Reviews of infectious diseases.

[41]  A Mügge,et al.  Echocardiography in infective endocarditis: reassessment of prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach. , 1989, Journal of the American College of Cardiology.

[42]  H. Neu,et al.  INFECTIVE ENDOCARDITIS—AN EVOLVING DISEASE: A Review of Endocarditis at The Columbia‐Presbyterian Medical Center, 1968–1973 , 1978, Medicine.

[43]  J. Aguado,et al.  Septic pulmonary emboli. A rare cause of bilateral pneumothorax in drug abusers. , 1990, Chest.

[44]  L. Evans,et al.  Central retinal artery occlusion in systemic lupus erythematosus. , 1983, Annals of ophthalmology.

[45]  A. Wakhloo,et al.  Microcatheter urokinase infusion in central retinal artery occlusion. , 1992, American journal of ophthalmology.

[46]  R. Koehler,et al.  Oxygen radical mechanisms of brain injury following ischemia and reperfusion. , 1991, Journal of applied physiology.

[47]  Lee Goldman,et al.  Cecil Textbook of Medicine , 1985 .

[48]  A. Patz,et al.  Vaso-occlusive retinopathy associated with antiphospholipid antibodies (lupus anticoagulant retinopathy). , 1989, Ophthalmology.

[49]  K. E. Frank,et al.  Actinobacillus actinomycetemcomitans endophthalmitis with subacute endocarditis. , 1984, Annals of ophthalmology.

[50]  H. Kolder,et al.  Central retinal artery occlusion and retinal tolerance time. , 1980, Ophthalmology.

[51]  J. Sheagren,et al.  Increased rate of carriage of Staphylococcus aureus among narcotic addicts. , 1974, The Journal of infectious diseases.

[52]  F. Munier,et al.  SUBRETINAL NEOVASCULARIZATION SECONDARY TO CHOROIDAL SEPTIC METASTASIS FROM ACUTE BACTERIAL ENDOCARDITIS , 1992, Retina.

[53]  G. Brown,et al.  Retinal arterial obstruction in children and young adults. , 1981, Ophthalmology.

[54]  S. Hayreh,et al.  Experimental occlusion of the central artery of the retina. IV: Retinal tolerance time to acute ischaemia. , 1980 .

[55]  Harris Mj Protection against ischaemia: the basis of acute stroke therapy. , 1992 .

[56]  A. Buchan Advances in cerebral ischemia: experimental approaches. , 1992, Neurologic clinics.

[57]  F. Bongard,et al.  Septic embolism complicating infective endocarditis. , 1991, Journal of vascular surgery.

[58]  D. Nakayama,et al.  Management of vascular complications of bacterial endocarditis. , 1986, Journal of pediatric surgery.

[59]  H. Zweng,et al.  Central retinal artery occlusion successfully treated with plasmin. , 1961, JAMA.

[60]  B. Siesjö,et al.  Influence of Acidosis on Lipid Peroxidation in Brain Tissues in vitro , 1985, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[61]  K. Karjalainen Occlusion of the central retinal artery and retinal branch arterioles. A clinical, tonographic and fluorescein angiographic study of 175 patients. , 1971, Acta ophthalmologica. Supplementum.

[62]  E. Kohner,et al.  Fundus signs in temporal arteritis. , 1978, The British journal of ophthalmology.

[63]  R. Dunn,et al.  Limitation of retinal injury by vitreoperfusion initiated after onset of ischemia. , 1991, Archives of ophthalmology.

[64]  B. Wechsler,et al.  [Arterial embolism of the limbs in infectious endocarditis of the heart valves]. , 1990, Presse medicale.

[65]  L. Magargal,et al.  Branch retinal-artery obstruction: a review of 201 eyes. , 1989, Annals of ophthalmology.

[66]  H. Engel,et al.  Transesophageal echocardiography in the diagnosis of branch retinal artery obstruction. , 1993, American journal of ophthalmology.

[67]  W. A. Manschot [Embolism of the central retinal artery originating from an endocardial myxoma]. , 1959, Nederlands tijdschrift voor geneeskunde.

[68]  D. Puro,et al.  Barbiturates protect retinal cells from hypoxia in cell culture. , 1989, A M A Archives of Ophthalmology.

[69]  W. Roberts,et al.  Infective endocarditis in opiate addicts: analysis of 80 cases studied at necropsy. , 1989, The American journal of cardiology.

[70]  J. Schlesinger,et al.  Pathoanatomic, pathophysiologic and clinical correlations in endocarditis (first of two parts). , 1974, The New England journal of medicine.

[71]  R. Adams,et al.  Principles of Neurology , 1996 .

[72]  I. Julander Staphylococcal septicaemia and endocarditis in 80 drug addicts. Aspects on epidemiology, clinical and laboratory findings and prognosis. , 1983, Scandinavian journal of infectious diseases. Supplementum.

[73]  I. Constable,et al.  A new method for oxygen supply to acute ischemic retina. , 1988, Investigative ophthalmology & visual science.

[74]  D. Durack,et al.  THE YALE JOURNAL OF BIOLOGY AND MEDICINE 50 (1977) The "Incubation Period " of Subacute Bacterial Endocarditis , 1976 .

[75]  P. Gallagher,et al.  Group B streptococcal endocarditis: report of seven cases and review of the literature, 1962-1985. , 1986, Reviews of infectious diseases.

[76]  A. Buda,et al.  Prognostic significance of vegetations detected by two-dimensional echocardiography in infective endocarditis. , 1986, American heart journal.

[77]  W. Edwards,et al.  Use of transesophageal echocardiography for improving detection of valvular vegetations in subacute bacterial endocarditis. , 1989, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[78]  S N Davies,et al.  Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. , 1988, Science.

[79]  M. Sise,et al.  Septic peripheral embolization from bacterial and fungal endocarditis , 1989, Annals of vascular surgery.

[80]  P. Ellis,et al.  Occlusion of the central retinal artery after retrobulbar corticosteroid injection. , 1978, American journal of ophthalmology.

[81]  K. Bailey,et al.  Emboli in infective endocarditis: the prognostic value of echocardiography. , 1991, Annals of internal medicine.

[82]  D. Pfaffenbach,et al.  Retinal arterial occlusion following ocular trauma in youths with sickle-trait hemoglobinopathy. , 1972, American journal of ophthalmology.

[83]  F. Walsh,et al.  Oral contraceptives and neuro-ophthalmologic interest. , 1965, Archives of ophthalmology.