eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B
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Seung-Jae V. Lee | S. Jang | Ka Young Hong | J. Kim | Junyoung Kwon | Eunah Kim | S. W. An | Keunhee Seo
[1] Joshua G. Dunn,et al. Translation from unconventional 5′ start sites drives tumour initiation , 2017, Nature.
[2] S. Jang,et al. An mRNA-specific tRNAi carrier eIF2A plays a pivotal role in cell proliferation under stress conditions: stress-resistant translation of c-Src mRNA is mediated by eIF2A , 2016, Nucleic acids research.
[3] A. Komar,et al. The eIF2A knockout mouse , 2016, Cell cycle.
[4] V. Ramakrishnan,et al. Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation , 2016, Cell.
[5] T. Mielke,et al. Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association , 2016, Science Advances.
[6] Peter Walter,et al. Translation from the 5′ untranslated region shapes the integrated stress response , 2016, Science.
[7] J. Puglisi,et al. Coupling of mRNA Structure Rearrangement to Ribosome Movement during Bypassing of Non-coding Regions , 2015, Cell.
[8] D. Boehringer,et al. Cryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution , 2015, Nature Communications.
[9] Michael J E Sternberg,et al. The Phyre2 web portal for protein modeling, prediction and analysis , 2015, Nature Protocols.
[10] A. Pisarev,et al. eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning , 2014, Nucleic acids research.
[11] T. Mielke,et al. Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA , 2014, Nature Structural &Molecular Biology.
[12] Alan G Hinnebusch,et al. The scanning mechanism of eukaryotic translation initiation. , 2014, Annual review of biochemistry.
[13] Yuxin Yin,et al. PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism. , 2014, Cell metabolism.
[14] Xavier Robert,et al. Deciphering key features in protein structures with the new ENDscript server , 2014, Nucleic Acids Res..
[15] S. Yokoyama,et al. Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe , 2014, Journal of Structural and Functional Genomics.
[16] V. Ramakrishnan,et al. Molecular Architecture of a Eukaryotic Translational Initiation Complex , 2013, Science.
[17] T. Steitz,et al. Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor , 2013, Proceedings of the National Academy of Sciences.
[18] Y. Mechulam,et al. Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA , 2012, Nucleic acids research.
[19] E. Meurs,et al. dsRNA-Dependent Protein Kinase PKR and its Role in Stress, Signaling and HCV Infection , 2012, Viruses.
[20] N. Shastri,et al. Leucine-tRNA Initiates at CUG Start Codons for Protein Synthesis and Presentation by MHC Class I , 2012, Science.
[21] Cole M. Haynes,et al. Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2 , 2012, PLoS genetics.
[22] Ji Hoon Park,et al. Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1 , 2011, Nucleic acids research.
[23] Sung Mi Park,et al. eIF2A mediates translation of hepatitis C viral mRNA under stress conditions , 2011, The EMBO journal.
[24] A. Komar,et al. Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling. , 2010, Genes & development.
[25] W. Merrick,et al. GTP-independent tRNA Delivery to the Ribosomal P-site by a Novel Eukaryotic Translation Factor* , 2010, The Journal of Biological Chemistry.
[26] M. Rodnina,et al. The ribosome‐bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex , 2010, EMBO reports.
[27] R. Jackson,et al. The mechanism of eukaryotic translation initiation and principles of its regulation , 2010, Nature Reviews Molecular Cell Biology.
[28] Colin Echeverría Aitken,et al. GTP hydrolysis by IF2 guides progression of the ribosome into elongation. , 2009, Molecular cell.
[29] A. Hinnebusch,et al. Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets , 2009, Cell.
[30] Bruno P. Klaholz,et al. Structure of the 30S translation initiation complex , 2008, Nature.
[31] D. Andreev,et al. Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2 , 2008, Nature Structural &Molecular Biology.
[32] S. Kimball,et al. Phosphorylation of eIF2alpha in response to 26S proteasome inhibition is mediated by the haem-regulated inhibitor (HRI) kinase. , 2008, The Biochemical journal.
[33] C. Hellen,et al. eIF2‐dependent and eIF2‐independent modes of initiation on the CSFV IRES: a common role of domain II , 2008, The EMBO journal.
[34] S. Marzi,et al. Functional analysis of the translation factor aIF2/5B in the thermophilic archaeon Sulfolobus solfataricus , 2007, Molecular microbiology.
[35] Jon R. Lorsch,et al. Coupled Release of Eukaryotic Translation Initiation Factors 5B and 1A from 80S Ribosomes following Subunit Joining , 2007, Molecular and Cellular Biology.
[36] J. Pelletier,et al. Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability. , 2006, Molecular biology of the cell.
[37] B. Conradt,et al. Eukaryotic translation initiation factor 5B activity regulates larval growth rate and germline development in Caenorhabditis elegans , 2006, Genesis.
[38] Y. Mechulam,et al. Initiator tRNA binding by e/aIF5B, the eukaryotic/archaeal homologue of bacterial initiation factor IF2. , 2005, Biochemistry.
[39] Joachim Frank,et al. The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli , 2005, Cell.
[40] A. Komar,et al. Novel Characteristics of the Biological Properties of the Yeast Saccharomyces cerevisiae Eukaryotic Initiation Factor 2A* , 2005, Journal of Biological Chemistry.
[41] C. Hellen,et al. Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP. , 2004, Genes & development.
[42] M. Ehrenberg,et al. The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis , 2003, The EMBO journal.
[43] A. Hinnebusch,et al. Direct eIF2–eIF3 contact in the multifactor complex is important for translation initiation in vivo , 2002, The EMBO journal.
[44] N. Sonenberg,et al. Regulation of Protein Synthesis by Hypoxia via Activation of the Endoplasmic Reticulum Kinase PERK and Phosphorylation of the Translation Initiation Factor eIF2α , 2002, Molecular and Cellular Biology.
[45] A. Komar,et al. Characterization of Mammalian eIF2A and Identification of the Yeast Homolog* , 2002, The Journal of Biological Chemistry.
[46] S. Kimball,et al. The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice , 2002, Molecular and Cellular Biology.
[47] A. Gingras,et al. Activation of GCN2 in UV-Irradiated Cells Inhibits Translation , 2002, Current Biology.
[48] Jane-Jane Chen,et al. Translation Initiation Control by Heme-Regulated Eukaryotic Initiation Factor 2α Kinase in Erythroid Cells under Cytoplasmic Stresses , 2001, Molecular and Cellular Biology.
[49] A. Hinnebusch,et al. Tight Binding of the Phosphorylated α Subunit of Initiation Factor 2 (eIF2α) to the Regulatory Subunits of Guanine Nucleotide Exchange Factor eIF2B Is Required for Inhibition of Translation Initiation , 2001, Molecular and Cellular Biology.
[50] Stephen K. Burley,et al. X-Ray Structures of the Universal Translation Initiation Factor IF2/eIF5B Conformational Changes on GDP and GTP Binding , 2000, Cell.
[51] D. Ron,et al. Perk is essential for translational regulation and cell survival during the unfolded protein response. , 2000, Molecular cell.
[52] C. Gualerzi,et al. The C-terminal Subdomain (IF2 C-2) Contains the Entire fMet-tRNA Binding Site of Initiation Factor IF2* , 2000, The Journal of Biological Chemistry.
[53] C. Hellen,et al. The joining of ribosomal subunits in eukaryotes requires eIF5B , 2000, Nature.
[54] N. Kyrpides,et al. Archaeal translation initiation revisited: the initiation factor 2 and eukaryotic initiation factor 2B alpha-beta-delta subunit families. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[55] A. Hinnebusch,et al. eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. , 1998, Genes & development.
[56] A. Hinnebusch,et al. Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2 , 1996, Molecular and cellular biology.
[57] E. M. Hannig,et al. Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma‐subunit. , 1996, The EMBO journal.
[58] C. Gualerzi,et al. Initiation of mRNA translation in prokaryotes. , 1990, Biochemistry.
[59] W. Anderson,et al. Purification and characterization of homogeneous protein synthesis initiation factor M1 from rabbit reticulocytes. , 1975, The Journal of biological chemistry.
[60] P. Londei,et al. Begin at the beginning: evolution of translational initiation. , 2009, Research in microbiology.
[61] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[62] Nikos,et al. Archaeal translation initiation revisited: The initiation factor 2 and eukaryotic initiation factor 2B a - b - d subunit families , 1998 .