Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.
暂无分享,去创建一个
J. Rich | N. Berger | J. Lathia | O. Reizes | A. Vasanji | S. Hursting | Sarah Fracci | Diana Basali | Q. Zheng | L. Banaszak | Sarah M. Dunlap | Anita B Hjlemeland | Sarah L. Fracci
[1] C. Perou,et al. Dietary Energy Balance Modulates Epithelial-to-Mesenchymal Transition and Tumor Progression in Murine Claudin-Low and Basal-like Mammary Tumor Models , 2012, Cancer Prevention Research.
[2] S. Catalano,et al. The multifactorial role of leptin in driving the breast cancer microenvironment , 2012, Nature Reviews Endocrinology.
[3] Swathi Bisana,et al. Mammary gland stem cells: More puzzles than explanations , 2012, Journal of Biosciences.
[4] P. Goodwin,et al. Insulin- and obesity-related variables in early-stage breast cancer: correlations and time course of prognostic associations. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[5] P. Dentelli,et al. A diabetic milieu promotes OCT4 and NANOG production in human visceral-derived adipose stem cells , 2012, Diabetologia.
[6] K. Machida,et al. Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells , 2011, Proceedings of the National Academy of Sciences.
[7] R. McLendon,et al. Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions , 2011, Cell Death and Disease.
[8] J. Rich,et al. Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. , 2011, Endocrine-related cancer.
[9] P. Scherer,et al. Leptin and cancer: from cancer stem cells to metastasis. , 2011, Endocrine-related cancer.
[10] J. Deschênes,et al. Increased risk of locoregional recurrence for women with T1-2N0 triple-negative breast cancer treated with modified radical mastectomy without adjuvant radiation therapy compared with breast-conserving therapy. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] I. Kovalszky,et al. Efficacy of a leptin receptor antagonist peptide in a mouse model of triple-negative breast cancer. , 2011, European journal of cancer.
[12] X. Chen,et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. , 2011, The Journal of clinical investigation.
[13] P. Scherer,et al. Paracrine and endocrine effects of adipose tissue on cancer development and progression. , 2011, Endocrine reviews.
[14] J. Shen,et al. NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation , 2011, Oncogene.
[15] Lisa A Carey,et al. Directed therapy of subtypes of triple-negative breast cancer. , 2010, The oncologist.
[16] F. Ghiringhelli,et al. Visceral fat area as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with antiangiogenic agents. , 2011, The oncologist.
[17] C. Hudis,et al. Triple-negative breast cancer: an unmet medical need. , 2011, The oncologist.
[18] M. Wicha,et al. Targeting breast cancer stem cells. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[19] C. Dive,et al. Biological mechanisms linking obesity and cancer risk: new perspectives. , 2010, Annual review of medicine.
[20] Hitoshi Niwa,et al. A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells , 2009, Nature.
[21] G. Vieten,et al. Obesity and the Associated Mediators Leptin, Estrogen and IGF-I Enhance the Cell Proliferation and Early Tumorigenesis of Breast Cancer Cells , 2009, Nutrition and cancer.
[22] G. Daley,et al. Functional Evidence that the Self‐Renewal Gene NANOG Regulates Human Tumor Development , 2009, Stem cells.
[23] F. Bertucci,et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. , 2009, Cancer research.
[24] M. Babb,et al. Influence of obesity on breast cancer receptor status and prognosis , 2009 .
[25] M. G. Myers,et al. Leptin receptor signaling and the regulation of mammalian physiology , 2008, International Journal of Obesity.
[26] N. Lin,et al. Sites of distant recurrence and clinical outcomes in patients with metastatic triple‐negative breast cancer , 2008, Cancer.
[27] P. Scherer,et al. The adipocyte as an endocrine cell. , 2008, Endocrinology and metabolism clinics of North America.
[28] Heike Münzberg,et al. Mechanisms of leptin action and leptin resistance. , 2008, Annual review of physiology.
[29] Carlos Caldas,et al. Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis , 2007, Nature Reviews Cancer.
[30] J. Rosen,et al. Modelling breast cancer: one size does not fit all , 2007, Nature Reviews Cancer.
[31] S. Narod,et al. Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence , 2007, Clinical Cancer Research.
[32] D. Rose,et al. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. , 2007, Endocrine-related cancer.
[33] C. Giordano,et al. Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression. , 2007, Cancer research.
[34] E. Surmacz. Obesity hormone leptin: a new target in breast cancer? , 2007, Breast Cancer Research.
[35] P. Leavis,et al. A peptide derived from the human leptin molecule is a potent inhibitor of the leptin receptor function in rabbit endometrial cells , 2003, Endocrine.
[36] Ian O Ellis,et al. Prognostic markers in triple‐negative breast cancer , 2007, Cancer.
[37] F. Anania,et al. Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways. , 2006, Endocrine-related cancer.
[38] E. Surmacz,et al. Leptin and cancer , 2006, Journal of cellular physiology.
[39] T. Funahashi,et al. High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels , 2006, International journal of cancer.
[40] A. Russo,et al. Increased Expression of Leptin and the Leptin Receptor as a Marker of Breast Cancer Progression: Possible Role of Obesity-Related Stimuli , 2006, Clinical Cancer Research.
[41] H. Nagawa,et al. Enhanced Expression of Leptin and Leptin Receptor (OB-R) in Human Breast Cancer , 2004, Clinical Cancer Research.
[42] Yihai Cao,et al. Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice , 2004, Circulation research.
[43] D. Mcfadden,et al. Leptin is a growth factor in cancer. , 2004, The Journal of surgical research.
[44] Michael J Thun,et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. , 2003, The New England journal of medicine.
[45] S. Morrison,et al. Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[46] Xin Hu,et al. Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development. , 2003, Journal of the National Cancer Institute.
[47] R. Tibshirani,et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[48] J. Flier,et al. Divergent Roles of SHP-2 in ERK Activation by Leptin Receptors* , 2001, The Journal of Biological Chemistry.
[49] Alexander S. Banks,et al. Activation of Downstream Signals by the Long Form of the Leptin Receptor* , 2000, The Journal of Biological Chemistry.
[50] J. Friedman. Leptin and the regulation of body weight. , 2010, Harvey lectures.
[51] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1995, Nature.
[52] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1994, Nature.
[53] F. Miller,et al. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. , 1992, Cancer research.