Salicylate Selectively Kills Cochlear Spiral Ganglion Neurons by Paradoxically Up-regulating Superoxide

[1]  R. Salvi,et al.  Salicylate-induced cochlear impairments, cortical hyperactivity and re-tuning, and tinnitus , 2013, Hearing Research.

[2]  J. Mehta,et al.  Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans. , 2013, Antioxidants & redox signaling.

[3]  Xiu-Li Shang,et al.  Effect of salicylate on the large GABAergic neurons in the inferior colliculus of rats , 2012, Acta Neurologica Belgica.

[4]  J. Denault,et al.  Label-free monitoring of apoptosis by surface plasmon resonance detection of morphological changes , 2012, Apoptosis.

[5]  J. Eberle,et al.  Nonsteroidal anti-inflammatory drugs induce apoptosis in cutaneous T-cell lymphoma cells and enhance their sensitivity for TNF-related apoptosis-inducing ligand. , 2012, The Journal of investigative dermatology.

[6]  R. Salvi,et al.  Salicylate-induced peripheral auditory changes and tonotopic reorganization of auditory cortex , 2011, Neuroscience.

[7]  Hao Feng,et al.  Blocking caspase-3-dependent pathway preserves hair cells from salicylate-induced apoptosis in the guinea pig cochlea , 2011, Molecular and Cellular Biochemistry.

[8]  H. Mori,et al.  Protective effects of fermented rice vinegar sediment (Kurozu moromimatsu) in a diethylnitrosamine-induced hepatocellular carcinoma animal model. , 2011 .

[9]  M. Asaka,et al.  Evaluation of gastrointestinal injury and blood flow of small bowel during low-dose aspirin administration , 2011, Journal of clinical biochemistry and nutrition.

[10]  Hao Feng,et al.  Salicylate Initiates Apoptosis in the Spiral Ganglion Neuron of Guinea Pig Cochlea by Activating Caspase-3 , 2011, Neurochemical Research.

[11]  A. Thompson,et al.  Activation of Serotonergic Neurons During Salicylate-Induced Tinnitus , 2011, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

[12]  Yan Li,et al.  Salicylate prevents hepatic oxidative stress activation caused by short-term elevation of free fatty acids in vivo. , 2010, Diabetes research and clinical practice.

[13]  Hao Feng,et al.  Caspase-3 activation in the guinea pig cochlea exposed to salicylate , 2010, Neuroscience Letters.

[14]  R. Salvi,et al.  Salicylate-induced degeneration of cochlea spiral ganglion neurons-apoptosis signaling , 2010, Neuroscience.

[15]  Guang-Di Chen,et al.  Too much of a good thing: Long-term treatment with salicylate strengthens outer hair cell function but impairs auditory neural activity , 2010, Hearing Research.

[16]  Josef Shargorodsky,et al.  Analgesic use and the risk of hearing loss in men. , 2010, The American journal of medicine.

[17]  Lei Wei.  Degeneration of cochlear SGNs caused by salicylate , 2010 .

[18]  R. Swanson,et al.  NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation , 2009, Nature Neuroscience.

[19]  B. Xiao,et al.  Long-term administration of salicylate enhances prestin expression in rat cochlea , 2009, International journal of audiology.

[20]  Ping Chen,et al.  [Effect of sodium salicylate on the auditory brain stem response threshold and expression of glutamic acid decarboxylase in spiral ganglion of juvenile and adult guinea pigs]. , 2008, Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery.

[21]  J. Duarte,et al.  Sodium salicylate prevents paraquat-induced apoptosis in the rat lung. , 2007, Free radical biology & medicine.

[22]  M. P. Berges-Gimeno,et al.  Allergic reactions to nonsteroidal anti-inflammatory drugs: Is newer better? , 2007, Current allergy and asthma reports.

[23]  M. Thun,et al.  A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence. , 2007, Journal of the National Cancer Institute.

[24]  J. Duarte,et al.  Full survival of paraquat-exposed rats after treatment with sodium salicylate. , 2007, Free radical biology & medicine.

[25]  Z. Darżynkiewicz,et al.  Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete “sub‐G1” peaks on DNA content histograms , 2007, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[26]  D. Dalian.  Experiences in ototoxic investigations in aminoglycoside antibiotics , 2007 .

[27]  J. Puel.  Cochlear NMDA receptor blockade prevents salicylate-induced tinnitus. , 2007, B-ENT.

[28]  H. Lee,et al.  Neuronal nitric oxide synthase expression in the cochlear nucleus in a salicylate model of tinnitus , 2006, Brain Research.

[29]  S. Gallus,et al.  Aspirin and cancer risk: an updated quantitative review to 2005 , 2006, Cancer Causes & Control.

[30]  S. Behar,et al.  Aspirin, Warfarin and a Thienopyridine for Acute Coronary Syndromes , 2006, Cardiology.

[31]  Takahiro Shimizu,et al.  Volume-sensitive Chloride Channels Involved in Apoptotic Volume Decrease and Cell Death , 2006, The Journal of Membrane Biology.

[32]  Min Young Kim,et al.  Implication of reactive oxygen species, ERK1/2, and p38MAPK in sodium salicylate-induced heat shock protein 72 expression in C6 glioma cells. , 2005, International journal of molecular medicine.

[33]  M. Salvi,et al.  Oxidative Stress Is Responsible for Mitochondrial Permeability Transition Induction by Salicylate in Liver Mitochondria* , 2005, Journal of Biological Chemistry.

[34]  E. Hoffmann,et al.  Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts , 2005, The Journal of physiology.

[35]  Hong-Bo Zhao,et al.  Paradoxical enhancement of active cochlear mechanics in long-term administration of salicylate. , 2005, Journal of neurophysiology.

[36]  S. Robinson,et al.  Aspirin-induced hepatic dysfunction in a patient with adult rheumatoid arthritis , 1976, The American Journal of Digestive Diseases.

[37]  J. Schacht,et al.  Antioxidant protection in a new animal model of cisplatin-induced ototoxicity , 2004, Hearing Research.

[38]  R. Salvi,et al.  Paraquat-Induced Hair Cell Damage and Protection with the Superoxide Dismutase Mimetic M40403 , 2004, Audiology and Neurotology.

[39]  Takahiro Shimizu,et al.  A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl(-) channel. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[40]  G. Ramesh,et al.  Salicylate reduces cisplatin nephrotoxicity by inhibition of tumor necrosis factor-alpha. , 2004, Kidney international.

[41]  G. Salvesen,et al.  Mechanisms of caspase activation. , 2003, Current opinion in cell biology.

[42]  J. Kordower,et al.  Inhibitors of Cyclooxygenase-2, but Not Cyclooxygenase-1 Provide Structural and Functional Protection against Quinolinic Acid-Induced Neurodegeneration , 2003, Journal of Pharmacology and Experimental Therapeutics.

[43]  Xi Lin,et al.  Aspirin selectively augmented N-methyl-d-aspartate types of glutamate responses in cultured spiral ganglion neurons of mice , 2003, Neuroscience Letters.

[44]  D. Brenner,et al.  Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[45]  Soo Young Lee,et al.  Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis. , 2003, Free radical biology & medicine.

[46]  C. la Vecchia,et al.  Aspirin and cancer risk: an update to 2001 , 2002, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[47]  Xiequn Chen,et al.  Sodium Salicylate—Triggered Apoptosis in HL-60 Cells Depends on Caspase-8 Activation , 2002, International journal of hematology.

[48]  J. Arezzo,et al.  Salicylate Protects Hearing and Kidney Function from Cisplatin Toxicity without Compromising its Oncolytic Action , 2002, Laboratory Investigation.

[49]  R. Salvi,et al.  Leupeptin protects cochlear and vestibular hair cells from gentamicin ototoxicity , 2002, Hearing Research.

[50]  A. Majid,et al.  Antiplatelet Agents for Secondary Prevention of Ischemic Stroke , 2001, The Annals of pharmacotherapy.

[51]  K. Valerie,et al.  Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation. , 2001, Molecular biology of the cell.

[52]  Y. Cazals.  Auditory sensori-neural alterations induced by salicylate , 2000, Progress in Neurobiology.

[53]  M. Pratten,et al.  Teratogenicity of Edoferon Kappa A, a Molecule Derived from Salicylate, in Cultured Rat Embryos: Differences from Salicylate and Interaction with Free Oxygen Radical Scavenging Enzymes , 2000, Anatomia, histologia, embryologia.

[54]  Y Ishizaki,et al.  Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[55]  M. Pratten,et al.  Protection by free oxygen radical scavenging enzymes against salicylate-induced embryonic malformations in vitro. , 2000, Toxicology in vitro : an international journal published in association with BIBRA.

[56]  W. Gao,et al.  Role of Neurotrophins and Lectins in Prevention of Ototoxicity , 1999, Annals of the New York Academy of Sciences.

[57]  F. Vittimberga,et al.  Salicylates Inhibit NF-κB Activation and Enhance TNF-α-Induced Apoptosis in Human Pancreatic Cancer Cells☆ , 1999 .

[58]  L. Klampfer,et al.  Sodium salicylate activates caspases and induces apoptosis of myeloid leukemia cell lines. , 1999, Blood.

[59]  F. Vittimberga,et al.  Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells. , 1999, The Journal of surgical research.

[60]  J. Vane,et al.  Mechanism of action of nonsteroidal anti-inflammatory drugs. , 1998, The American journal of medicine.

[61]  C. Hiramine.  [Definition and morphological features of apoptosis]. , 1997, Rinsho byori. The Japanese journal of clinical pathology.

[62]  M. Memo,et al.  Neuroprotection by Aspirin and Sodium Salicylate Through Blockade of NF-κB Activation , 1996, Science.

[63]  W. Gao,et al.  Differential Damage to Auditory Neurons and Hair Cells by Ototoxins and Neuroprotection by Specific Neurotrophins in Rat Cochlear Organotypic Cultures , 1996, The European journal of neuroscience.

[64]  H. Shinkawa,et al.  NMDA (NMDAR1) and AMPA‐type (GluR2/3) receptor subunits are expressed in the inner ear , 1995, Neuroreport.

[65]  R. Wenthold,et al.  Expression of AMPA, kainate, and NMDA receptor subunits in cochlear and vestibular ganglia , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[66]  D. Rachmilewitz,et al.  A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats. , 1994, Gut.

[67]  R. Albin,et al.  Expression of NMDA-receptor mRNA in the rat cochlea , 1993, Hearing Research.

[68]  J. Bockaert,et al.  NMDA-dependent superoxide production and neurotoxicity , 1993, Nature.

[69]  A. S. Salim.  Use of scavenging oxygen-derived free radicals to protect the rat against aspirin- and ethanol-induced erosive gastritis. , 1992, Journal of pharmaceutical sciences.

[70]  G. Moonen,et al.  Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse , 1991, Brain Research.

[71]  R. Salvi,et al.  Salicylate ototoxicity: review and synthesis. , 1991, American journal of otolaryngology.

[72]  K. Brandt.  The mechanism of action of nonsteroidal antiinflammatory drugs. , 1991, The Journal of rheumatology. Supplement.

[73]  R. Bobbin,et al.  Salicylate, mefenamate, meclofenamate, and quinine on cochlear potentials , 1990, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[74]  D. McFadden,et al.  Aspirin-induced hearing loss as a model of sensorineural hearing loss , 1984, Hearing Research.

[75]  R D Emkey,et al.  Aspirin and renal disease. , 1983, The American journal of medicine.

[76]  A. Wyllie,et al.  Cell death: the significance of apoptosis. , 1980, International review of cytology.

[77]  John D. Davis,et al.  Pirprofen and aspirin in the treatment of rheumatoid arthritis , 1979, Clinical pharmacology and therapeutics.

[78]  A. Wyllie,et al.  Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.

[79]  J. Bernstein,et al.  SALICYLATE OTOTOXICITY: A CLINICAL STUDY. , 1965, The New England journal of medicine.